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- References [14]
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- Product number
- 10170-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10170-1-AP, RRID:AB_2082384
- Product name
- Complement factor B antibody
- Antibody type
- Polyclonal
- Description
- Complement factor B antibody (Cat. #10170-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references In situ assessment of glomerular C3/C5 convertases indicates ongoing complement activation in IgA nephropathy.
Mutations in UMOD Contribute to the Pathogenesis of ADTKD-UMOD by Influencing the Function of Complement Factor H.
Identification of serum protein biomarkers for pre-cancerous lesions associated with pancreatic ductal adenocarcinoma.
Inflammation Is More Sensitive than Cell Proliferation in Response to Rapamycin Treatment in Polycystic Kidney Disease.
Complement activation in wasp venom-induced acute kidney injury.
The classical pathway triggers pathogenic complement activation in membranous nephropathy.
The influences of α-hemolytic Streptococcus on class switching and complement activation of human tonsillar cells in IgA nephropathy.
IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium.
Complement factor B regulates cellular senescence and is associated with poor prognosis in pancreatic cancer.
The imbalance in the complement system and its possible physiological mechanisms in patients with lung cancer.
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
Resveratrol delays polycystic kidney disease progression through attenuation of nuclear factor κB-induced inflammation.
Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.
The C-terminal tail of polycystin-1 regulates complement factor B expression by signal transducer and activator of transcription 1.
Obrecht A, Meuleman MS, Olagne J, Grunenwald A, Chauvet S, Roumenina L, Frémeaux-Bacchi V, Caillard S, Duval A
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2026 Mar 31;41(4):715-724
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2026 Mar 31;41(4):715-724
Mutations in UMOD Contribute to the Pathogenesis of ADTKD-UMOD by Influencing the Function of Complement Factor H.
Xie Q, Bai L, Gong K, Hu N, Chen Y
Journal of cellular and molecular medicine 2026 Jan;30(2):e71025
Journal of cellular and molecular medicine 2026 Jan;30(2):e71025
Identification of serum protein biomarkers for pre-cancerous lesions associated with pancreatic ductal adenocarcinoma.
Mearns H, Long JS, Lilla S, Hodge K, Ladds MJGW, Nixon C, Fernández-Palanca P, Zanivan S, Acedo P, Pereira SP, Ryan KM
Molecular oncology 2026 Feb 18;
Molecular oncology 2026 Feb 18;
Inflammation Is More Sensitive than Cell Proliferation in Response to Rapamycin Treatment in Polycystic Kidney Disease.
Yang M, Lv J, Gong C, Xue C, Fu L, Chen S, Mei C
Kidney & blood pressure research 2024;49(1):60-68
Kidney & blood pressure research 2024;49(1):60-68
Complement activation in wasp venom-induced acute kidney injury.
Cheng R, Xu L, Gong J, Yu F, Lv Y, Yuan H, Hu F
Renal failure 2024 Dec;46(1):2344658
Renal failure 2024 Dec;46(1):2344658
The classical pathway triggers pathogenic complement activation in membranous nephropathy.
Seifert L, Zahner G, Meyer-Schwesinger C, Hickstein N, Dehde S, Wulf S, Köllner SMS, Lucas R, Kylies D, Froembling S, Zielinski S, Kretz O, Borodovsky A, Biniaminov S, Wang Y, Cheng H, Koch-Nolte F, Zipfel PF, Hopfer H, Puelles VG, Panzer U, Huber TB, Wiech T, Tomas NM
Nature communications 2023 Jan 28;14(1):473
Nature communications 2023 Jan 28;14(1):473
The influences of α-hemolytic Streptococcus on class switching and complement activation of human tonsillar cells in IgA nephropathy.
Ye M, Wang C, Li L, Zhao Q, Peng Y, Liu H
Immunologic research 2022 Feb;70(1):86-96
Immunologic research 2022 Feb;70(1):86-96
IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium.
Cheng X, He D, Liao C, Lin S, Tang L, Wang YL, Hu J, Li W, Liu Z, Wu Y, Liao Y
Journal of cellular physiology 2021 May;236(5):3660-3674
Journal of cellular physiology 2021 May;236(5):3660-3674
Complement factor B regulates cellular senescence and is associated with poor prognosis in pancreatic cancer.
Shimazaki R, Takano S, Satoh M, Takada M, Miyahara Y, Sasaki K, Yoshitomi H, Kagawa S, Furukawa K, Takayashiki T, Kuboki S, Sogawa K, Motohashi S, Nomura F, Miyazaki M, Ohtsuka M
Cellular oncology (Dordrecht, Netherlands) 2021 Aug;44(4):937-950
Cellular oncology (Dordrecht, Netherlands) 2021 Aug;44(4):937-950
The imbalance in the complement system and its possible physiological mechanisms in patients with lung cancer.
Zhao P, Wu J, Lu F, Peng X, Liu C, Zhou N, Ying M
BMC cancer 2019 Mar 6;19(1):201
BMC cancer 2019 Mar 6;19(1):201
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
Linetsky M, Bondelid KS, Losovskiy S, Gabyak V, Rullo MJ, Stiadle TI, Munjapara V, Saxena P, Ma D, Cheng YS, Howes AM, Udeigwe E, Salomon RG
Chemical research in toxicology 2018 Aug 20;31(8):666-679
Chemical research in toxicology 2018 Aug 20;31(8):666-679
Resveratrol delays polycystic kidney disease progression through attenuation of nuclear factor κB-induced inflammation.
Wu M, Gu J, Mei S, Xu D, Jing Y, Yao Q, Chen M, Yang M, Chen S, Yang B, Qi N, Hu H, Wüthrich RP, Mei C
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2016 Nov;31(11):1826-1834
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2016 Nov;31(11):1826-1834
Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.
Jin Y, Wang J, Ye X, Su Y, Yu G, Yang Q, Liu W, Yu W, Cai J, Chen X, Liang Y, Chen Y, Wong BH, Fu X, Sun H
British journal of cancer 2016 Mar 1;114(5):532-44
British journal of cancer 2016 Mar 1;114(5):532-44
The C-terminal tail of polycystin-1 regulates complement factor B expression by signal transducer and activator of transcription 1.
Wu M, Chen M, Jing Y, Gu J, Mei S, Yao Q, Zhou J, Yang M, Sun L, Wang W, Hu H, Wüthrich RP, Mei C
American journal of physiology. Renal physiology 2016 Jun 1;310(11):F1284-94
American journal of physiology. Renal physiology 2016 Jun 1;310(11):F1284-94
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Complement factor B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Complement factor B. This antibody recognizes human antigen. The Complement factor B antibody has been validated for the following applications: ELISA, WB analysis.
