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- References [20]
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- Immunohistochemistry [2]
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- Product number
- 14632-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14632-1-AP, RRID:AB_2091264
- Product name
- DDX6 antibody
- Antibody type
- Polyclonal
- Description
- DDX6 antibody (Cat. #14632-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Contrastive learning of dynamic processing body formation reveals undefined mechanisms of approved compounds.
Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK-3β/β-Catenin Signaling.
C9orf72 ALS-causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules.
Systematic characterization of the composition and dynamics of processing body-associated mRNAs.
The RNA-Binding Protein IGF2BP1 Marks Germ Cells but Is Dispensable for Mouse Fertility.
DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance.
CCHCR1 links P-body proteins to the centrosome and is required for ciliogenesis through interacting with OFD1 and PCM1.
DDX6 modulates P-body and stress granule assembly, composition, and docking.
Energy stress promotes P-bodies formation via lysine-63-linked polyubiquitination of HAX1.
LSM14B coordinates protein component expression in the P-body and controls oocyte maturation.
Candidate biomarkers in brown adipose tissue for post-mortem diagnosis of fatal hypothermia.
Primate-Specific DAZ Regulates Translation of Cell Proliferation-Related mRNAs and is Essential for Maintenance of Spermatogonia.
Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing.
DDX6 is involved in the pathogenesis of inflammatory diseases via NF-κB activation.
PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities.
LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.
NUSAP1 regulates mouse oocyte meiotic maturation.
SpotitPy: a semi-automated tool for object-based co-localization of fluorescent labels in microscopy images.
The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex.
Translational activation of developmental messenger RNAs during neonatal mouse testis development.
Shen D, Zhu Q, Pang X, Pan D, Copo Amador MC, Zhang M, Li Y, Sun Z, Cao Z, Yang X, Fang L, Chen W, Tsuboi T
iScience 2026 Mar 20;29(3):114866
iScience 2026 Mar 20;29(3):114866
Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK-3β/β-Catenin Signaling.
Fan X, Guo D, Li S, Tian J, Zhang C, Li Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e04680
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e04680
C9orf72 ALS-causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules.
Bilican S, Nabawi Y, Zhang WH, Petrovic D, Wehrmann M, Muñoz-García S, Koyuncu S, Vilchez D
FEBS letters 2025 Nov;599(21):3047-3065
FEBS letters 2025 Nov;599(21):3047-3065
Systematic characterization of the composition and dynamics of processing body-associated mRNAs.
Sun Z, Wen X, Li Y, Xie X, Dong P, Shu Y, Tian S, Yang J, Lin Y, Wang M, Jiang F, Zhu Q, Cui H, Zhai J, Hu Y, Fang L, Chen W
Nature communications 2025 Nov 10;16(1):9867
Nature communications 2025 Nov 10;16(1):9867
The RNA-Binding Protein IGF2BP1 Marks Germ Cells but Is Dispensable for Mouse Fertility.
Wang S, Wu S, Tang J, Chen Y, Zhang Y, Long W, Wu X
Molecular reproduction and development 2025 Feb;92(2):e70016
Molecular reproduction and development 2025 Feb;92(2):e70016
DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance.
Bi H, Li W, Ren L, Zhang H, Dong L, Chan A, Wang X, Yang L, Zhang X, Xue M, Qin H, Wu X, Hoeve-Scott JT, Zhang B, Li L, Wunderlich M, Mulloy JC, Rosen ST, Chen J, Li X, Chen CW, Su R
Nature communications 2025 Dec 2;17(1):260
Nature communications 2025 Dec 2;17(1):260
CCHCR1 links P-body proteins to the centrosome and is required for ciliogenesis through interacting with OFD1 and PCM1.
Zhang J, Wu Q, Zhang S, Sze SCW, Li C
Cellular & molecular biology letters 2025 Aug 29;30(1):103
Cellular & molecular biology letters 2025 Aug 29;30(1):103
DDX6 modulates P-body and stress granule assembly, composition, and docking.
Ripin N, Macedo de Vasconcelos L, Ugay DA, Parker R
The Journal of cell biology 2024 Jun 3;223(6)
The Journal of cell biology 2024 Jun 3;223(6)
Energy stress promotes P-bodies formation via lysine-63-linked polyubiquitination of HAX1.
Zhan W, Li Z, Zhang J, Liu Y, Liu G, Li B, Shen R, Jiang Y, Shang W, Gao S, Wu H, Wang Y, Chen W, Wang Z
The EMBO journal 2024 Jul;43(13):2759-2788
The EMBO journal 2024 Jul;43(13):2759-2788
LSM14B coordinates protein component expression in the P-body and controls oocyte maturation.
Zhang H, Zhang T, Wan X, Chen C, Wang S, Qin D, Li L, Yu L, Wu X
Journal of genetics and genomics = Yi chuan xue bao 2024 Jan;51(1):48-60
Journal of genetics and genomics = Yi chuan xue bao 2024 Jan;51(1):48-60
Candidate biomarkers in brown adipose tissue for post-mortem diagnosis of fatal hypothermia.
Zhang M, Wang N, Guo XS, Wang LL, Wang PF, Cao ZP, Zhang FY, Wang ZW, Guan DW, Zhao R
International journal of legal medicine 2024 Jan;138(1):61-72
International journal of legal medicine 2024 Jan;138(1):61-72
Primate-Specific DAZ Regulates Translation of Cell Proliferation-Related mRNAs and is Essential for Maintenance of Spermatogonia.
Ou N, Wang Y, Xu S, Luo J, Zhang C, Zhang Y, Shi X, Xiong M, Zhao L, Ji Z, Zhang Y, Zhao J, Bai H, Tian R, Li P, Zhi E, Huang Y, Chen W, Wang R, Jin Y, Wang D, Li Z, Chen H, Yao C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400692
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400692
Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing.
Maneix L, Iakova P, Lee CG, Moree SE, Lu X, Datar GK, Hill CT, Spooner E, King JCK, Sykes DB, Saez B, Di Stefano B, Chen X, Krause DS, Sahin E, Tsai FTF, Goodell MA, Berk BC, Scadden DT, Catic A
Nature cell biology 2024 Apr;26(4):593-603
Nature cell biology 2024 Apr;26(4):593-603
DDX6 is involved in the pathogenesis of inflammatory diseases via NF-κB activation.
Naito S, Tanaka H, Jiang JJ, Tarumi M, Hashimoto A, Tanaka Y, Murakami K, Kubota SI, Hojyo S, Hashimoto S, Murakami M
Biochemical and biophysical research communications 2024 Apr 9;703:149666
Biochemical and biophysical research communications 2024 Apr 9;703:149666
PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities.
Đukić N, Strømland Ø, Elsborg JD, Munnur D, Zhu K, Schuller M, Chatrin C, Kar P, Duma L, Suyari O, Rack JGM, Baretić D, Crudgington DRK, Groslambert J, Fowler G, Wijngaarden S, Prokhorova E, Rehwinkel J, Schüler H, Filippov DV, Sanyal S, Ahel D, Nielsen ML, Smith R, Ahel I
Science advances 2023 Sep 15;9(37):eadi2687
Science advances 2023 Sep 15;9(37):eadi2687
LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.
Wan Y, Yang S, Li T, Cai Y, Wu X, Zhang M, Muhammad T, Huang T, Lv Y, Chan WY, Lu G, Li J, Sha QQ, Chen ZJ, Liu H
Nucleic acids research 2023 Nov 27;51(21):11652-11667
Nucleic acids research 2023 Nov 27;51(21):11652-11667
NUSAP1 regulates mouse oocyte meiotic maturation.
Yu L, Kong N, Lin Y, Qiu P, Xu Q, Zhang Y, Zhen X, Yan G, Sun H, Mei J, Cao G
Journal of cellular biochemistry 2023 Dec;124(12):1931-1947
Journal of cellular biochemistry 2023 Dec;124(12):1931-1947
SpotitPy: a semi-automated tool for object-based co-localization of fluorescent labels in microscopy images.
Akalestou-Clocher A, Kalamara V, Topalis P, Garinis GA
BMC bioinformatics 2022 Oct 21;23(1):439
BMC bioinformatics 2022 Oct 21;23(1):439
The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex.
Zou L, Moch C, Graille M, Chapat C
iScience 2022 Jul 15;25(7):104646
iScience 2022 Jul 15;25(7):104646
Translational activation of developmental messenger RNAs during neonatal mouse testis development.
Chappell VA, Busada JT, Keiper BD, Geyer CB
Biology of reproduction 2013 Sep;89(3):61
Biology of reproduction 2013 Sep;89(3):61
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 14632-1-AP(P54 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 14632-1-AP(P54 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The P54 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human P54. This antibody recognizes human,mouse,rat antigen. The P54 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
