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- Antibody Data
- Antigen structure
- References [15]
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- Validations
- Western blot [1]
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- Product number
- 15439-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15439-1-AP, RRID:AB_2224154
- Product name
- AKR1B1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AKR1B1 antibody (Cat. #15439-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Multi-omics analysis and preliminary experimental validation of acetyl tributyl citrate (ATBC) promoting bladder cancer progression via the AKR1B1/EMT axis.
Fructose and glucose from sugary drinks enhance colorectal cancer metastasis via SORD.
Exploration and validation of a novel reactive oxygen species-related signature for predicting the prognosis and chemotherapy response of patients with bladder cancer.
Baicalin administration could rescue high glucose-induced craniofacial skeleton malformation by regulating neural crest development.
Differential metabolites screening in yak (Bos grunniens) seminal plasma after cryopreservation and the evaluation of the effect of galactose on post-thaw sperm motility.
Circular RNA LMBR1 inhibits bladder cancer progression by enhancing expression of the protein ALDH1A3.
A pro-metastatic tRNA fragment drives aldolase A oligomerization to enhance aerobic glycolysis in lung adenocarcinoma.
Construction and experimental validation of a macrophage cell senescence-related gene signature to evaluate the prognosis, immunotherapeutic sensitivity, and chemotherapy response in bladder cancer.
AKR1B1 Represses Glioma Cell Proliferation through p38 MAPK-Mediated Bcl-2/BAX/Caspase-3 Apoptotic Signaling Pathways.
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Seminal plasma of men with severe asthenozoospermia contain exosomes that affect spermatozoa motility and capacitation.
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells.
Jie J, Wang Q, Chen Z, Hu C, Lai Z, Ke S, Zhu Y, Li F, Fan Q, Tan W
Environmental pollution (Barking, Essex : 1987) 2026 May 15;397:127970
Environmental pollution (Barking, Essex : 1987) 2026 May 15;397:127970
Fructose and glucose from sugary drinks enhance colorectal cancer metastasis via SORD.
Feng T, Luo Q, Liu Y, Jin Z, Skwarchuk D, Lee R, Nam M, Asara JM, Adye DR, Lorenzi PL, Tan L, Pei G, Zhao Z, Zarrin-Khameh N, Paulucci-Holthauzen A, Simons BW, Lee JS, Kopetz S, Yun J
Nature metabolism 2025 Oct;7(10):2018-2032
Nature metabolism 2025 Oct;7(10):2018-2032
Exploration and validation of a novel reactive oxygen species-related signature for predicting the prognosis and chemotherapy response of patients with bladder cancer.
Li Y, Zhang L, Xu G, Xu G, Chen J, Zhao K, Li M, Jin J, Peng C, Wang K, Pan S, Zhu K
Frontiers in immunology 2024;15:1493528
Frontiers in immunology 2024;15:1493528
Baicalin administration could rescue high glucose-induced craniofacial skeleton malformation by regulating neural crest development.
Lu JQ, Luo ZY, Sun C, Wang SM, Sun D, Huang RJ, Yang X, Ding Y, Wang G
Frontiers in pharmacology 2024;15:1295356
Frontiers in pharmacology 2024;15:1295356
Differential metabolites screening in yak (Bos grunniens) seminal plasma after cryopreservation and the evaluation of the effect of galactose on post-thaw sperm motility.
Fan Y, Li X, Li J, Xiong X, Yin S, Fu W, Wang P, Liu J, Xiong Y
Theriogenology 2024 Feb;215:249-258
Theriogenology 2024 Feb;215:249-258
Circular RNA LMBR1 inhibits bladder cancer progression by enhancing expression of the protein ALDH1A3.
Lv Y, Yuan Z, Chen D, Chen Z, Zhu X, Ying X, Huang Y, Ji W, Qi D
Non-coding RNA research 2024 Dec;9(4):1235-1248
Non-coding RNA research 2024 Dec;9(4):1235-1248
A pro-metastatic tRNA fragment drives aldolase A oligomerization to enhance aerobic glycolysis in lung adenocarcinoma.
Wang Q, Song X, Zhang Y, Liang S, Zhang M, Wang H, Feng Y, Li R, Ding H, Chen Y, Xia W, Dong G, Xu L, Mao Q, Jiang F
Cell reports 2024 Aug 27;43(8):114550
Cell reports 2024 Aug 27;43(8):114550
Construction and experimental validation of a macrophage cell senescence-related gene signature to evaluate the prognosis, immunotherapeutic sensitivity, and chemotherapy response in bladder cancer.
Jiang Q, Zhou J, Chen Q, Huang Y, Yang C, Liu C
Functional & integrative genomics 2023 Jul 10;23(3):228
Functional & integrative genomics 2023 Jul 10;23(3):228
AKR1B1 Represses Glioma Cell Proliferation through p38 MAPK-Mediated Bcl-2/BAX/Caspase-3 Apoptotic Signaling Pathways.
Huang YK, Chang KC, Li CY, Lieu AS, Lin CL
Current issues in molecular biology 2023 Apr 13;45(4):3391-3405
Current issues in molecular biology 2023 Apr 13;45(4):3391-3405
Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis.
Huang Q, Zhang F, Liu S, Jiang Y, Ouyang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Aug;140:111735
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, Chi T, Zou L, Wang S, He Z
Oxidative medicine and cellular longevity 2020;2020:7950457
Oxidative medicine and cellular longevity 2020;2020:7950457
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Jun 15;397:115014
Toxicology and applied pharmacology 2020 Jun 15;397:115014
Seminal plasma of men with severe asthenozoospermia contain exosomes that affect spermatozoa motility and capacitation.
Murdica V, Giacomini E, Alteri A, Bartolacci A, Cermisoni GC, Zarovni N, Papaleo E, Montorsi F, Salonia A, Viganò P, Vago R
Fertility and sterility 2019 May;111(5):897-908.e2
Fertility and sterility 2019 May;111(5):897-908.e2
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Wang Z, Yuan S, Li Y, Zhang Z, Xiao W, Tang D, Ye K, Liu Z, Wang C, Zheng Y, Nie H, Chen H
Biochemical pharmacology 2018 Apr;150:54-63
Biochemical pharmacology 2018 Apr;150:54-63
Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells.
Lu Y, Wang J, Dapeng C, Wu D, Cai G, Chen X
BMC nephrology 2016 Apr 1;17:39
BMC nephrology 2016 Apr 1;17:39
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AKR1B1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AKR1B1. This antibody recognizes human, mouse, rat antigen. The AKR1B1 antibody has been validated for the following applications: ELISA, WB analysis.
