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- Antibody Data
- Antigen structure
- References [16]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 19495-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19495-1-AP, RRID:AB_10640579
- Product name
- Aldehyde oxidase antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Aldehyde oxidase antibody (Cat. #19495-1-AP) is a rabbit polyclonal antibody that shows reactivity with mouse, rat, Canidae and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Acute E2/P4 loss compromises the biology and function of neurogenic niches during a vulnerable female aging period.
Integrated metabolomics and mass spectrometry imaging analysis reveal the efficacy and mechanism of Huangkui capsule on type 2 diabetic nephropathy.
Systems Network Integration of Transcriptomic, Proteomic, and Bioinformatic Analyses Reveals the Mechanism of XuanYunNing Tablets in Meniere's Disease via JAK-STAT Pathway Modulation.
Contribution of aldehyde oxidase to methotrexate-induced hepatotoxicity: in vitro and pharmacoepidemiological approaches.
Time-restricted feeding ameliorates non-alcoholic fatty liver disease through modulating hepatic nicotinamide metabolism via gut microbiota remodeling.
Aldehyde oxidase 1 promotes gallbladder carcinogenesis through ROS-mediated activation of the Wnt/β-catenin pathway.
Bioinformatics-Guided Analysis Uncovers AOX1 as an Osteogenic Differentiation-Relevant Gene of Human Mesenchymal Stem Cells.
Insight of a Metabolic Prognostic Model to Identify Tumor Environment and Drug Vulnerability for Lung Adenocarcinoma.
The rs35217482 (T755I) single-nucleotide polymorphism in aldehyde oxidase-1 attenuates prot ein dimer formation and reduces the rates of phthalazine metabolism.
Expression of AOX1 Predicts Prognosis of Clear Cell Renal Cell Carcinoma.
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
Curc-mPEG454, a PEGylated curcumin derivative, as a multi-target anti-fibrotic prodrug.
Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression.
Protective effects of L-theanine on rats with dextran sulfate sodium-induced inflammatory bowel disease.
Evidence that fetal death is associated with placental aging.
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice.
Pillutla SV, Skoda MJ, Ishii A, Corenblum MJ, Montogomery T, Wene P, Menakuru N, Kraszewski JN, Billheimer D, Winter GM, Cowen SL, Madhavan L
bioRxiv : the preprint server for biology 2025 May 13;
bioRxiv : the preprint server for biology 2025 May 13;
Integrated metabolomics and mass spectrometry imaging analysis reveal the efficacy and mechanism of Huangkui capsule on type 2 diabetic nephropathy.
Han J, Li P, Sun H, Zheng Y, Liu C, Chen X, Guan S, Yin F, Wang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156397
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156397
Systems Network Integration of Transcriptomic, Proteomic, and Bioinformatic Analyses Reveals the Mechanism of XuanYunNing Tablets in Meniere's Disease via JAK-STAT Pathway Modulation.
Jin Z, Wang C, Gao Y, Tao X, Wu C, Guo S, Huang J, Zhou J, Qiao C, Chai K, Chang H, Li C, Zou X, Wu J
Pharmaceuticals (Basel, Switzerland) 2025 Aug 25;18(9)
Pharmaceuticals (Basel, Switzerland) 2025 Aug 25;18(9)
Contribution of aldehyde oxidase to methotrexate-induced hepatotoxicity: in vitro and pharmacoepidemiological approaches.
Moriyama A, Ueda H, Narumi K, Asano S, Furugen A, Saito Y, Kobayashi M
Expert opinion on drug metabolism & toxicology 2024 May;20(5):399-406
Expert opinion on drug metabolism & toxicology 2024 May;20(5):399-406
Time-restricted feeding ameliorates non-alcoholic fatty liver disease through modulating hepatic nicotinamide metabolism via gut microbiota remodeling.
Feng R, Yang W, Feng W, Huang X, Cen M, Peng G, Wu W, Wang Z, Jing Y, Long T, Liu Y, Li Z, Chang G, Huang K
Gut microbes 2024 Jan-Dec;16(1):2390164
Gut microbes 2024 Jan-Dec;16(1):2390164
Aldehyde oxidase 1 promotes gallbladder carcinogenesis through ROS-mediated activation of the Wnt/β-catenin pathway.
Yuan Z, Yi G, Ma R, Wang Z, Hu J, Zhao W, Hu Y
Cellular signalling 2024 Apr;116:111042
Cellular signalling 2024 Apr;116:111042
Bioinformatics-Guided Analysis Uncovers AOX1 as an Osteogenic Differentiation-Relevant Gene of Human Mesenchymal Stem Cells.
Sun L, Ma J, Chen J, Pan Z, Li L
Frontiers in molecular biosciences 2022;9:800288
Frontiers in molecular biosciences 2022;9:800288
Insight of a Metabolic Prognostic Model to Identify Tumor Environment and Drug Vulnerability for Lung Adenocarcinoma.
Peng SL, Wang R, Zhou YL, Wei W, Zhong GH, Huang XT, Yang S, Liu QD, Liu ZG
Frontiers in immunology 2022;13:872910
Frontiers in immunology 2022;13:872910
The rs35217482 (T755I) single-nucleotide polymorphism in aldehyde oxidase-1 attenuates prot ein dimer formation and reduces the rates of phthalazine metabolism.
Ueda H, Narumi K, Furugen A, Saito Y, Kobayashi M
Drug metabolism and disposition: the biological fate of chemicals 2022 Jul 16;50(9)
Drug metabolism and disposition: the biological fate of chemicals 2022 Jul 16;50(9)
Expression of AOX1 Predicts Prognosis of Clear Cell Renal Cell Carcinoma.
Xiong L, Feng Y, Hu W, Tan J, Li S, Wang H
Frontiers in genetics 2021;12:683173
Frontiers in genetics 2021;12:683173
PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
Chen X, Xu Y, Denning KL, Grigore A, Lu Y
Free radical biology & medicine 2021 Jun;169:283-293
Free radical biology & medicine 2021 Jun;169:283-293
Curc-mPEG454, a PEGylated curcumin derivative, as a multi-target anti-fibrotic prodrug.
Xiao S, Deng Y, Shen N, Sun Y, Tang H, Hu P, Ren H, Peng M
International immunopharmacology 2021 Dec;101(Pt A):108166
International immunopharmacology 2021 Dec;101(Pt A):108166
Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression.
Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri N
Oncogene 2020 Oct;39(40):6265-6285
Oncogene 2020 Oct;39(40):6265-6285
Protective effects of L-theanine on rats with dextran sulfate sodium-induced inflammatory bowel disease.
Chen L, Xiao WJ, Yan QX, Gong ZH, Zhang S, Zeng L, Yang M, Zhou YH
Archives of pharmacal research 2020 Aug;43(8):821-862
Archives of pharmacal research 2020 Aug;43(8):821-862
Evidence that fetal death is associated with placental aging.
Maiti K, Sultana Z, Aitken RJ, Morris J, Park F, Andrew B, Riley SC, Smith R
American journal of obstetrics and gynecology 2017 Oct;217(4):441.e1-441.e14
American journal of obstetrics and gynecology 2017 Oct;217(4):441.e1-441.e14
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice.
Zidek LM, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, Leutz A, Sonenberg N, Wang ZQ, von Maltzahn J, Müller C, Calkhoven CF
EMBO reports 2015 Aug;16(8):1022-36
EMBO reports 2015 Aug;16(8):1022-36
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 19495-1-AP(AOX1 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using AOX1 antibody 19495-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hepatocirrhosis using 19495-1-AP(AOX1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hepatocirrhosis using 19495-1-AP(AOX1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
