Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19699-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19699-1-AP, RRID:AB_10696174
- Product name
- LIMK1 antibody
- Antibody type
- Polyclonal
- Description
- LIMK1 antibody (Cat. #19699-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mechanism of Gzma-mediated GEF-H1 activation in intestinal epithelial cells leading to intestinal barrier dysfunction in sepsis.
Blockade of ITGA2/3/5 Promotes Adipogenic Differentiation of Human Adipose-derived Mesenchymal Stem Cells.
B7-H3 promotes the migration and invasion of colorectal cancer cells via regulating the actin cytoskeleton and RhoA/ROCK1/LIMK1 signaling pathway.
LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling.
Septin11 promotes hepatocellular carcinoma cell motility by activating RhoA to regulate cytoskeleton and cell adhesion.
FMNL2 suppresses cell migration and invasion of breast cancer: a reduction of cytoplasmic p27 via RhoA/LIMK/Cofilin pathway.
FOXD3‑AS1/miR‑128‑3p/LIMK1 axis regulates cervical cancer progression.
Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.
MiR-145 inhibits human colorectal cancer cell migration and invasion via PAK4-dependent pathway.
Lin Z, Jiang H, Ni C, Deng L, Yang H, Wang R, Liu P, Li X, Yu Y, Li W, Liao B, Liu J, Li W, Yang J, Chao Y, Liu H, Wu X, Ren J, Zhao Y
Clinical and translational medicine 2026 Apr;16(4):e70651
Clinical and translational medicine 2026 Apr;16(4):e70651
Blockade of ITGA2/3/5 Promotes Adipogenic Differentiation of Human Adipose-derived Mesenchymal Stem Cells.
Li Y, Wang W, Liu Z, Liu G, Li X
Cell biochemistry and biophysics 2025 Mar;83(1):1105-1111
Cell biochemistry and biophysics 2025 Mar;83(1):1105-1111
B7-H3 promotes the migration and invasion of colorectal cancer cells via regulating the actin cytoskeleton and RhoA/ROCK1/LIMK1 signaling pathway.
Zhao A, Zhu X, Wu H, Wang J, Zhang M, Xiang J, Xia S, Shi T, Xi Q
Tissue & cell 2024 Oct;90:102518
Tissue & cell 2024 Oct;90:102518
LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
Hu G, Huang N, Zhang J, Zhang D, Wang S, Zhang Y, Wang L, Du Y, Kuang S, Ma K, Zhu H, Xu N, Liu M
Molecular carcinogenesis 2023 Nov;62(11):1659-1672
Molecular carcinogenesis 2023 Nov;62(11):1659-1672
RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling.
Zhu H, Wen Z, Zhang A, Liu D, Wang H, Cheng Y, Yang X, Xiao Y, Li J, Sun D, Wu B, Gao J
Communications biology 2023 Feb 23;6(1):214
Communications biology 2023 Feb 23;6(1):214
Septin11 promotes hepatocellular carcinoma cell motility by activating RhoA to regulate cytoskeleton and cell adhesion.
Fu L, Wang X, Yang Y, Chen M, Kuerban A, Liu H, Dong Y, Cai Q, Ma M, Wu X
Cell death & disease 2023 Apr 20;14(4):280
Cell death & disease 2023 Apr 20;14(4):280
FMNL2 suppresses cell migration and invasion of breast cancer: a reduction of cytoplasmic p27 via RhoA/LIMK/Cofilin pathway.
Jiao X, Wang B, Yang L, Zhao Q, Zhang M, Liu X, Zhou C, Wang R, Chen H, Wang J, Ren Y, Liu P
Cell death discovery 2022 Apr 4;8(1):155
Cell death discovery 2022 Apr 4;8(1):155
FOXD3‑AS1/miR‑128‑3p/LIMK1 axis regulates cervical cancer progression.
Yang X, Du H, Bian W, Li Q, Sun H
Oncology reports 2021 May;45(5)
Oncology reports 2021 May;45(5)
Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation.
Zhang Y, Li A, Shi J, Fang Y, Gu C, Cai J, Lin C, Zhao L, Liu S
Cell death & disease 2018 Jul 3;9(7):749
Cell death & disease 2018 Jul 3;9(7):749
MiR-145 inhibits human colorectal cancer cell migration and invasion via PAK4-dependent pathway.
Sheng N, Tan G, You W, Chen H, Gong J, Chen D, Zhang H, Wang Z
Cancer medicine 2017 Jun;6(6):1331-1340
Cancer medicine 2017 Jun;6(6):1331-1340
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 19699-1-AP(LIMK1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 19699-1-AP(LIMK1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The LIMK1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human LIMK1. This antibody recognizes human,mouse,rat antigen. The LIMK1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.