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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [86]
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- Product number
- 60035-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60035-1-Ig, RRID:AB_2058598
- Product name
- ATF4 antibody
- Antibody type
- Monoclonal
- Description
- ATF4 antibody (Cat. #60035-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3E4C5
- Vial size
- 20ul, 150ul
Submitted references Microvascular endothelial metabolic dysfunction drives cerebral edema through bioenergetic failure after ischemia-reperfusion.
SIRT3 promotes oxaliplatin sensitivity in hepatocellular carcinoma by promoting ferroptosis through endoplasmic reticulum stress response.
Novel Dual-Pharmacophore TrxR Inhibitors Integrating Ferroptosis and Antitumor Immunity: A Closed-Loop Strategy for TIME Remodeling.
Inhibition of α-1,3-mannosyltransferase sensitizes head and neck squamous cell carcinomas to cetuximab via endoplasmic reticulum stress.
PERK-eIF2alpha-mediated translational inhibition of MCL-1 contributes to potential 2-deoxy-D-glucose and BAD mimetic combinatorial cancer therapy.
XIAP Stabilizes DDRGK1 to Promote ER-Phagy and Protects Against Noise-Induced Hearing Loss.
Natural photosynthetic system for restoring homeostasis of animal organelle interaction network.
Chronic short sleep in early life accelerates cognitive decline via disrupted proteostasis.
Targeting UGCG sensitizes AML cells to venetoclax through RAB32-mediated endoplasmic reticulum-mitochondria communication.
Ferulic Acid Alleviates Chemotherapy-Induced POI by Targeting the Grp78 and Perk-eIF2α-ATF4-CHOP Pathway to Attenuate Endoplasmic Reticulum Stress.
Pharmacological Enhancement of Integrated Stress Response Confers Protection in Calcific Aortic Valve Disease.
Eugenol alleviates renal ischemia-reperfusion injury induced-endoplasmic reticulum stress via activating Sestrin2.
Activated AXL Ameliorates Alcohol-associated Steatotic Liver Ischemia-Reperfusion Injury by Inhibiting ER stress and Mitochondria-associated Apoptosis.
Modulating Macrophage-Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration.
Gestational exposure to micro- and nanoplastics leads to poor pregnancy outcomes by impairing placental trophoblast syncytialization.
FAM172A deletion aggravates high fat diet-induced MASLD via the eIF2α-ATF4-FGF21 loop.
cZFP609 Tethering BiP Alleviates Cartilage Degradation in Osteoarthritis via Remedying Aberrant ER-Mitochondrial Contacts.
DNAJB2 Attenuates Rosacea Skin Inflammation and Angiogenesis by Inhibiting the Endoplasmic Reticulum Stress-mediated TLR2/Myd88/NF-κB pathway.
Usenamine A, an RGS2 inhibitor, exerts anti-NSCLC activity and enhances cytotoxicity of gemcitabine by inducing ER stress and Notch1-mediated autophagy.
Crucial roles of GALNT6-mediated O-glycosylation of GRP78/Bip in proliferation of breast cancer cells.
Unfolded protein response-activated NLRP3 inflammasome contributes to pyroptotic and apoptotic podocyte injury in diabetic kidney disease via the CHOP-TXNIP axis.
CD44 Deficiency Induces Combinatory NRF2 Inhibition and Endoplasmic Reticulum Stress-Associated Dyserythropoiesis.
Differential ER stress responses during lactation and postpartum outcomes in mice depending on their mitochondrial genotype.
6-Shogaol Alleviates Endotoxin-Induced Uveitis via Activation of HIF-1α to Regulate Inflammatory Responses and Endoplasmic Reticulum Stress.
A natural small molecule alleviates liver fibrosis by targeting apolipoprotein L2.
LINC00626 drives tamoxifen resistance in breast cancer cells by interaction with UPF1.
Sensory quiescence induces a cell-non-autonomous integrated stress response curbed by condensate formation of the ATF4 and XRP1 effectors.
Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice.
Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1.
TARGETING S100A9-TLR2 AXIS CONTROLS MACROPHAGE NLRP3 INFLAMMASOME ACTIVATION IN FATTY LIVER ISCHEMIA REPERFUSION INJURY.
Interaction Between Activating Transcription Factor 4 and Interleukin 6 Dictates Osteoclast Differentiation and Activity.
Chromatin remodeler Chd7 regulates reactive astrogliosis after ischemic stroke.
Palmatine activation of TFEB enhances autophagy and alleviates endoplasmic reticulum stress in intervertebral disc degeneration.
N6-methyladenosine modification of LATS2 promotes hepatoblastoma progression by inhibiting ferroptosis through the YAP1/ATF4/PSAT1 axis.
MicroRNA-3145 as a potential therapeutic target for hepatitis B virus: inhibition of viral replication via downregulation of HBS and HBX.
Nimbolide protects against diabetic cardiomyopathy by regulating endoplasmic reticulum stress and mitochondrial function via the Akt/mTOR pathway.
Melatonin Protects Against Mitochondrial Dyshomeostasis and Ovarian Damage Caused by Chronic Unpredictable Mild Stress Through the eIF2α-AFT4 Signaling Pathway in Mice.
Gut microbiota-derived acetic acids promoted sepsis-induced acute respiratory distress syndrome by delaying neutrophil apoptosis through FABP4.
PDZD8 Augments Endoplasmic Reticulum-Mitochondria Contact and Regulates Ca2+ Dynamics and Cypd Expression to Induce Pancreatic β-Cell Death during Diabetes.
Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis.
Isoliquiritigenin induced hepatotoxicity and endoplasmic reticulum stress in zebrafish embryos.
Upregulation of neuronal ER-phagy improves organismal fitness and alleviates APP toxicity.
Mutant U2AF1-Induced Mis-Splicing of mRNA Translation Genes Confers Resistance to Chemotherapy in Acute Myeloid Leukemia.
Advanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop.
CHIP suppresses the proliferation and migration of A549 cells by mediating the ubiquitination of eIF2α and upregulation of tumor suppressor RBM5.
Prevotella histicola ameliorates DSS-induced colitis by inhibiting IRE1α-JNK pathway of ER stress and NF-κB signaling.
Idiosyncratic nature of lactation reveals link to breast cancer risk.
Evaluation of Cross-Talk and Alleviate Potential of Cytotoxic Factors Induced by Deoxynivalenol in IPEC-J2 Cells Interference with Curcumin.
Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice.
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
Human umbilical cord mesenchymal stem cells improve the ovarian function through oxidative stress-mediated PERK/eIF-2α/ATF4/CHOP signaling in premature ovarian insufficiency mice.
Vitamin E Mitigates Apoptosis in Ovarian Granulosa Cells by Inhibiting Zearalenone-Induced Activation of the PERK/eIF-2α/ATF4/Chop Signaling Pathway.
Ethanol-Induced Hepatic Ferroptosis Is Mediated by PERK-Dependent MAMs Formation: Preventive Role of Quercetin.
ATF4 knockdown in macrophage impairs glycolysis and mediates immune tolerance by targeting HK2 and HIF-1α ubiquitination in sepsis.
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Comparative multi-omic analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency.
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Early and late chaperone intervention therapy boosts XBP1s and ADAM10, restores proteostasis, and rescues learning in Alzheimer's Disease mice.
CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology.
Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation.
Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation.
Forsythiaside A ameliorates sepsis-induced acute kidney injury via anti-inflammation and antiapoptotic effects by regulating endoplasmic reticulum stress.
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Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.
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The portrait of liver cancer is shaped by mitochondrial genetics.
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
N6-methyladenosine demethylase FTO regulates inflammatory cytokine secretion and tight junctions in retinal pigment epithelium cells.
CCDC106 promotes the proliferation and invasion of ovarian cancer cells by suppressing p21 transcription through a p53-independent pathway.
Cystine and Methionine Deficiency Promotes Ferroptosis by Inducing B-Cell Translocation Gene 1.
ATF4-mediated GDF15 suppresses LPS-induced inflammation and MUC5AC in human nasal epithelial cells through the PI3K/Akt pathway.
The regulation of ferroptosis by MESH1 through the activation of the integrative stress response.
Sestrin2 protects against lethal sepsis by suppressing the pyroptosis of dendritic cells.
Doxycycline promotes proteasome fitness in the central nervous system.
In vitro effects of Triclocarban on adipogenesis in murine preadipocyte and human hepatocyte.
Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy.
Function and mutual interaction of BiP-, PERK-, and IRE1α-dependent signalling pathways in vascular tumours.
Downregulation of folate receptor α contributes to homocysteine‑induced human umbilical vein endothelial cell injury via activation of endoplasmic reticulum stress.
FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma.
ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis.
Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis.
Oxysterol-binding protein-related protein 8 (ORP8) increases sensitivity of hepatocellular carcinoma cells to Fas-mediated apoptosis.
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SIRT3 promotes oxaliplatin sensitivity in hepatocellular carcinoma by promoting ferroptosis through endoplasmic reticulum stress response.
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PERK-eIF2alpha-mediated translational inhibition of MCL-1 contributes to potential 2-deoxy-D-glucose and BAD mimetic combinatorial cancer therapy.
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Chronic short sleep in early life accelerates cognitive decline via disrupted proteostasis.
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Targeting UGCG sensitizes AML cells to venetoclax through RAB32-mediated endoplasmic reticulum-mitochondria communication.
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Eugenol alleviates renal ischemia-reperfusion injury induced-endoplasmic reticulum stress via activating Sestrin2.
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Activated AXL Ameliorates Alcohol-associated Steatotic Liver Ischemia-Reperfusion Injury by Inhibiting ER stress and Mitochondria-associated Apoptosis.
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FAM172A deletion aggravates high fat diet-induced MASLD via the eIF2α-ATF4-FGF21 loop.
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cZFP609 Tethering BiP Alleviates Cartilage Degradation in Osteoarthritis via Remedying Aberrant ER-Mitochondrial Contacts.
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DNAJB2 Attenuates Rosacea Skin Inflammation and Angiogenesis by Inhibiting the Endoplasmic Reticulum Stress-mediated TLR2/Myd88/NF-κB pathway.
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Differential ER stress responses during lactation and postpartum outcomes in mice depending on their mitochondrial genotype.
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Sensory quiescence induces a cell-non-autonomous integrated stress response curbed by condensate formation of the ATF4 and XRP1 effectors.
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Disrupted methionine cycle triggers muscle atrophy in cancer cachexia through epigenetic regulation of REDD1.
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N6-methyladenosine modification of LATS2 promotes hepatoblastoma progression by inhibiting ferroptosis through the YAP1/ATF4/PSAT1 axis.
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Diabetes & metabolism journal 2024 Nov;48(6):1058-1072
Diabetes & metabolism journal 2024 Nov;48(6):1058-1072
Lactate activates ER stress to promote alveolar epithelial cells apoptosis in pulmonary fibrosis.
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Respiratory research 2024 Nov 9;25(1):401
Respiratory research 2024 Nov 9;25(1):401
Isoliquiritigenin induced hepatotoxicity and endoplasmic reticulum stress in zebrafish embryos.
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Scientific reports 2024 Nov 16;14(1):28256
Scientific reports 2024 Nov 16;14(1):28256
Upregulation of neuronal ER-phagy improves organismal fitness and alleviates APP toxicity.
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Cell reports 2024 May 28;43(5):114255
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Advanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop.
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CHIP suppresses the proliferation and migration of A549 cells by mediating the ubiquitination of eIF2α and upregulation of tumor suppressor RBM5.
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Prevotella histicola ameliorates DSS-induced colitis by inhibiting IRE1α-JNK pathway of ER stress and NF-κB signaling.
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Research square 2024 Jun 28;
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Evaluation of Cross-Talk and Alleviate Potential of Cytotoxic Factors Induced by Deoxynivalenol in IPEC-J2 Cells Interference with Curcumin.
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Sephin1 enhances integrated stress response and autophagy to alleviate myocardial ischemia-reperfusion injury in mice.
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Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
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Experimental cell research 2024 Feb 15;435(2):113945
Experimental cell research 2024 Feb 15;435(2):113945
Human umbilical cord mesenchymal stem cells improve the ovarian function through oxidative stress-mediated PERK/eIF-2α/ATF4/CHOP signaling in premature ovarian insufficiency mice.
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Molecular biology reports 2024 Dec 26;52(1):85
Molecular biology reports 2024 Dec 26;52(1):85
Vitamin E Mitigates Apoptosis in Ovarian Granulosa Cells by Inhibiting Zearalenone-Induced Activation of the PERK/eIF-2α/ATF4/Chop Signaling Pathway.
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Journal of agricultural and food chemistry 2024 Dec 25;72(51):28390-28399
Journal of agricultural and food chemistry 2024 Dec 25;72(51):28390-28399
Ethanol-Induced Hepatic Ferroptosis Is Mediated by PERK-Dependent MAMs Formation: Preventive Role of Quercetin.
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Molecular nutrition & food research 2024 Apr;68(7):e2300343
ATF4 knockdown in macrophage impairs glycolysis and mediates immune tolerance by targeting HK2 and HIF-1α ubiquitination in sepsis.
Liu T, Wen Z, Shao L, Cui Y, Tang X, Miao H, Shi J, Jiang L, Feng S, Zhao Y, Zhang H, Liang Q, Chen D, Zhang Y, Wang C
Clinical immunology (Orlando, Fla.) 2023 Sep;254:109698
Clinical immunology (Orlando, Fla.) 2023 Sep;254:109698
Visual impairment cell non-autonomously dysregulates brain-wide proteostasis.
Shekhar S, Wert KJ, Krämer H
bioRxiv : the preprint server for biology 2023 Oct 23;
bioRxiv : the preprint server for biology 2023 Oct 23;
Comparative multi-omic analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency.
Sayles NM, Napierala JS, Anrather J, Diedhiou N, Li J, Napierala M, Puccio H, Manfredi G
Disease models & mechanisms 2023 Oct 1;16(10)
Disease models & mechanisms 2023 Oct 1;16(10)
The Critical Role of The Piezo1/β-catenin/ATF4 Axis on The Stemness of Gli1(+) BMSCs During Simulated Microgravity-Induced Bone Loss.
Hu Y, Tian H, Chen W, Liu Y, Cao Y, Pei H, Ming C, Shan C, Chen X, Dai Z, Yang S, Shao Z, Lan S, Liu Y, Tong W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2303375
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2303375
Early and late chaperone intervention therapy boosts XBP1s and ADAM10, restores proteostasis, and rescues learning in Alzheimer's Disease mice.
Hafycz JM, Strus E, Naidoo NN
bioRxiv : the preprint server for biology 2023 May 24;
bioRxiv : the preprint server for biology 2023 May 24;
CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology.
Gouveia Roque C, Chung KM, McCurdy EP, Jagannathan R, Randolph LK, Herline-Killian K, Baleriola J, Hengst U
Science advances 2023 Mar 3;9(9):eadd2671
Science advances 2023 Mar 3;9(9):eadd2671
Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons.
Mun SH, Lee CS, Kim HJ, Kim J, Lee H, Yang J, Im SH, Kim JH, Seong JK, Hwang CS
Cell reports 2023 Jul 25;42(7):112746
Cell reports 2023 Jul 25;42(7):112746
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, Alam S, Liparulo I, Shurubor YI, Valentino ML, Carelli V, Servidei S, Gross SS, Manfredi G, Chen Q, D'Aurelio M
EMBO molecular medicine 2023 Jul 10;15(7):e16951
EMBO molecular medicine 2023 Jul 10;15(7):e16951
KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation.
Hua Q, Lu Y, Wang D, Da J, Peng W, Sun G, Gu K, Wang H, Zhu Y
Translational oncology 2023 Feb;28:101617
Translational oncology 2023 Feb;28:101617
Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation.
Yu J, Shen S, Yan Y, Liu L, Luo R, Liu S, Wu Y, Li Y, Jiang J, Ying H
Nutrients 2023 Feb 9;15(4)
Nutrients 2023 Feb 9;15(4)
Forsythiaside A ameliorates sepsis-induced acute kidney injury via anti-inflammation and antiapoptotic effects by regulating endoplasmic reticulum stress.
Chen Y, Wei W, Fu J, Zhang T, Zhao J, Ma T
BMC complementary medicine and therapies 2023 Feb 3;23(1):35
BMC complementary medicine and therapies 2023 Feb 3;23(1):35
ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis.
Gao Y, Feng L, Zhang L, Geng J, Zhang E
Disease markers 2022;2022:7527996
Disease markers 2022;2022:7527996
Exosomal DNAJB11 promotes the development of pancreatic cancer by modulating the EGFR/MAPK pathway.
Liu P, Zu F, Chen H, Yin X, Tan X
Cellular & molecular biology letters 2022 Oct 8;27(1):87
Cellular & molecular biology letters 2022 Oct 8;27(1):87
Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats.
Zhong Y, Li Z, Jin R, Yao Y, He S, Lei M, Wang X, Shi C, Gao L, Peng X
Nutrients 2022 Nov 24;14(23)
Nutrients 2022 Nov 24;14(23)
Reducing ER stress with chaperone therapy reverses sleep fragmentation and cognitive decline in aged mice.
Hafycz JM, Strus E, Naidoo N
Aging cell 2022 Jun;21(6):e13598
Aging cell 2022 Jun;21(6):e13598
Benzaldehyde Attenuates the Fifth Stage Larval Excretory-Secretory Product of Angiostrongylus cantonensis-Induced Injury in Mouse Astrocytes via Regulation of Endoplasmic Reticulum Stress and Oxidative Stress.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Biomolecules 2022 Jan 21;12(2)
Biomolecules 2022 Jan 21;12(2)
The portrait of liver cancer is shaped by mitochondrial genetics.
Chattopadhyay M, Jenkins EC, Lechuga-Vieco AV, Nie K, Fiel MI, Rialdi A, Guccione E, Enriquez JA, Sia D, Lujambio A, Germain D
Cell reports 2022 Jan 18;38(3):110254
Cell reports 2022 Jan 18;38(3):110254
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
Xu Z, Xu J, Sun S, Lin W, Li Y, Lu Q, Li F, Yang Z, Lu Y, Liu W
Redox biology 2022 Aug;54:102351
Redox biology 2022 Aug;54:102351
N6-methyladenosine demethylase FTO regulates inflammatory cytokine secretion and tight junctions in retinal pigment epithelium cells.
Tang S, Meng J, Tan J, Liu X, Zhou H, Li N, Hou S
Clinical immunology (Orlando, Fla.) 2022 Aug;241:109080
Clinical immunology (Orlando, Fla.) 2022 Aug;241:109080
CCDC106 promotes the proliferation and invasion of ovarian cancer cells by suppressing p21 transcription through a p53-independent pathway.
Zhao N, Wang C, Guo P, Hou J, Yang H, Lan T, Zhou Y, Li J, Bhawal UK, Liu Y
Bioengineered 2022 Apr;13(4):10956-10972
Bioengineered 2022 Apr;13(4):10956-10972
Cystine and Methionine Deficiency Promotes Ferroptosis by Inducing B-Cell Translocation Gene 1.
Cho IJ, Kim D, Kim EO, Jegal KH, Kim JK, Park SM, Zhao R, Ki SH, Kim SC, Ku SK
Antioxidants (Basel, Switzerland) 2021 Sep 28;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 28;10(10)
ATF4-mediated GDF15 suppresses LPS-induced inflammation and MUC5AC in human nasal epithelial cells through the PI3K/Akt pathway.
Li A, Zhao F, Zhao Y, Liu H, Wang Z
Life sciences 2021 Jun 15;275:119356
Life sciences 2021 Jun 15;275:119356
The regulation of ferroptosis by MESH1 through the activation of the integrative stress response.
Lin CC, Ding CC, Sun T, Wu J, Chen KY, Zhou P, Chi JT
Cell death & disease 2021 Jul 22;12(8):727
Cell death & disease 2021 Jul 22;12(8):727
Sestrin2 protects against lethal sepsis by suppressing the pyroptosis of dendritic cells.
Wang LX, Ren C, Yao RQ, Luo YN, Yin Y, Wu Y, Dong N, Zhu XM, Yao YM
Cellular and molecular life sciences : CMLS 2021 Dec;78(24):8209-8227
Cellular and molecular life sciences : CMLS 2021 Dec;78(24):8209-8227
Doxycycline promotes proteasome fitness in the central nervous system.
Jenkins EC, O'Connell MJ, Manfredi G, Germain D
Scientific reports 2021 Aug 20;11(1):17003
Scientific reports 2021 Aug 20;11(1):17003
In vitro effects of Triclocarban on adipogenesis in murine preadipocyte and human hepatocyte.
Dong M, Yuan P, Song Y, Lei H, Chen G, Zhu X, Wu F, Chen C, Liu C, Shi Z, Zhang L
Journal of hazardous materials 2020 Nov 15;399:122829
Journal of hazardous materials 2020 Nov 15;399:122829
Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy.
Wu J, Wu Y, Lian X
Biology open 2020 Nov 12;9(11)
Biology open 2020 Nov 12;9(11)
Function and mutual interaction of BiP-, PERK-, and IRE1α-dependent signalling pathways in vascular tumours.
Anspach L, Tsaryk R, Seidmann L, Unger RE, Jayasinghe C, Simiantonaki N, Kirkpatrick CJ, Pröls F
The Journal of pathology 2020 Jun;251(2):123-134
The Journal of pathology 2020 Jun;251(2):123-134
Downregulation of folate receptor α contributes to homocysteine‑induced human umbilical vein endothelial cell injury via activation of endoplasmic reticulum stress.
Cui J, Cao C, Hu H, Zhang H, Yang Y, Wang L, Huang X, Li P
Molecular medicine reports 2020 Aug;22(2):1631-1638
Molecular medicine reports 2020 Aug;22(2):1631-1638
FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma.
Zhao Y, Yu Y, Li H, Zhang Z, Guo S, Zhu S, Guo Q, Li P, Min L, Zhang S
Molecular oncology 2019 May;13(5):1150-1165
Molecular oncology 2019 May;13(5):1150-1165
ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis.
Dey S, Sayers CM, Verginadis II, Lehman SL, Cheng Y, Cerniglia GJ, Tuttle SW, Feldman MD, Zhang PJ, Fuchs SY, Diehl JA, Koumenis C
The Journal of clinical investigation 2015 Jul 1;125(7):2592-608
The Journal of clinical investigation 2015 Jul 1;125(7):2592-608
Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis.
Wu H, Wei L, Fan F, Ji S, Zhang S, Geng J, Hong L, Fan X, Chen Q, Tian J, Jiang M, Sun X, Jin C, Yin ZY, Liu Q, Zhang J, Qin F, Lin KH, Yu JS, Deng X, Wang HR, Zhao B, Johnson RL, Chen L, Zhou D
Nature communications 2015 Feb 19;6:6239
Nature communications 2015 Feb 19;6:6239
Oxysterol-binding protein-related protein 8 (ORP8) increases sensitivity of hepatocellular carcinoma cells to Fas-mediated apoptosis.
Zhong W, Qin S, Zhu B, Pu M, Liu F, Wang L, Ye G, Yi Q, Yan D
The Journal of biological chemistry 2015 Apr 3;290(14):8876-87
The Journal of biological chemistry 2015 Apr 3;290(14):8876-87
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