ABIN401040

antibody from antibodies-online

Targeting: CFLAR c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN401040

Provider

antibodies-online

Product name

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to amino acids near the carboxyl terminus of the HumanFLIPalpha/FLIPL proteinGenename: CFLAR

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

0.1 mg

Concentration

0.5 mg/ml (by UV absorbance at 280 nm)

Storage

Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

References

Submitted references

Casper is a FADD- and caspase-related inducer of apoptosis.

Shu HB, Halpin DR, Goeddel DV
Immunity 1997 Jun;6(6):751-63

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I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis.

Hu S, Vincenz C, Ni J, Gentz R, Dixit VM
The Journal of biological chemistry 1997 Jul 11;272(28):17255-7

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Inhibition of death receptor signals by cellular FLIP.

Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schröter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J
Nature 1997 Jul 10;388(6638):190-5

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Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors.

Thome M, Schneider P, Hofmann K, Fickenscher H, Meinl E, Neipel F, Mattmann C, Burns K, Bodmer JL, Schröter M, Scaffidi C, Krammer PH, Peter ME, Tschopp J
Nature 1997 Apr 3;386(6624):517-21