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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- H00001491-M02 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00001491-M02, RRID:AB_538057
- Product name
- Mouse Monoclonal Cystathionase Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. CTH - cystathionase (cystathionine gamma-lyase)
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Distinctive expression pattern of cystathionine-β-synthase and cystathionine-γ-lyase identifies mesenchymal stromal cells transition to mineralizing osteoblasts.
Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency.
Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression.
Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap.
Hydrogen sulfide mitigates cardiac remodeling during myocardial infarction via improvement of angiogenesis.
Integrated stress response modulates cellular redox state via induction of cystathionine γ-lyase: cross-talk between integrated stress response and thiol metabolism.
Folic acid improves inner ear vascularization in hyperhomocysteinemic mice.
A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment.
Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation.
Gambari L, Lisignoli G, Gabusi E, Manferdini C, Paolella F, Piacentini A, Grassi F
Journal of cellular physiology 2017 Dec;232(12):3574-3585
Journal of cellular physiology 2017 Dec;232(12):3574-3585
Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency.
Grassi F, Tyagi AM, Calvert JW, Gambari L, Walker LD, Yu M, Robinson J, Li JY, Lisignoli G, Vaccaro C, Adams J, Pacifici R
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2016 May;31(5):949-63
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2016 May;31(5):949-63
Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression.
Panza E, De Cicco P, Armogida C, Scognamiglio G, Gigantino V, Botti G, Germano D, Napolitano M, Papapetropoulos A, Bucci M, Cirino G, Ianaro A
Pigment cell & melanoma research 2015 Jan;28(1):61-72
Pigment cell & melanoma research 2015 Jan;28(1):61-72
Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap.
Jiang H, Hurt KJ, Breen K, Stabler SP, Allen RH, Orlicky DJ, Maclean KN
Biology open 2015 Aug 14;4(9):1154-62
Biology open 2015 Aug 14;4(9):1154-62
Hydrogen sulfide mitigates cardiac remodeling during myocardial infarction via improvement of angiogenesis.
Qipshidze N, Metreveli N, Mishra PK, Lominadze D, Tyagi SC
International journal of biological sciences 2012;8(4):430-41
International journal of biological sciences 2012;8(4):430-41
Integrated stress response modulates cellular redox state via induction of cystathionine γ-lyase: cross-talk between integrated stress response and thiol metabolism.
Dickhout JG, Carlisle RE, Jerome DE, Mohammed-Ali Z, Jiang H, Yang G, Mani S, Garg SK, Banerjee R, Kaufman RJ, Maclean KN, Wang R, Austin RC
The Journal of biological chemistry 2012 Mar 2;287(10):7603-14
The Journal of biological chemistry 2012 Mar 2;287(10):7603-14
Folic acid improves inner ear vascularization in hyperhomocysteinemic mice.
Kundu S, Munjal C, Tyagi N, Sen U, Tyagi AC, Tyagi SC
Hearing research 2012 Feb;284(1-2):42-51
Hearing research 2012 Feb;284(1-2):42-51
A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment.
Maclean KN, Sikora J, Kožich V, Jiang H, Greiner LS, Kraus E, Krijt J, Overdier KH, Collard R, Brodsky GL, Meltesen L, Crnic LS, Allen RH, Stabler SP, Elleder M, Rozen R, Patterson D, Kraus JP
Molecular genetics and metabolism 2010 Oct-Nov;101(2-3):153-62
Molecular genetics and metabolism 2010 Oct-Nov;101(2-3):153-62
Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation.
d'Emmanuele di Villa Bianca R, Sorrentino R, Maffia P, Mirone V, Imbimbo C, Fusco F, De Palma R, Ignarro LJ, Cirino G
Proceedings of the National Academy of Sciences of the United States of America 2009 Mar 17;106(11):4513-8
Proceedings of the National Academy of Sciences of the United States of America 2009 Mar 17;106(11):4513-8
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Cystathionase Antibody (2E12-1C10) [H00001491-M02] - CTH monoclonal antibody (M02), clone 2E12-1C10 Analysis of CTH expression in K-562.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Sandwich ELISA: Cystathionase Antibody (2E12-1C10) [H00001491-M02] - Detection limit for recombinant GST tagged CTH is approximately 1ng/ml as a capture antibody.
