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LearnABIN401263
antibody from antibodies-online
Targeting: PRKDC
DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, p350, p460, XRCC7
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- ABIN401263 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (Thr2609) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide corresponding to amino acids surrounding Thr 2609 of Human DNA PKcs
- Description
- Immunoaffinity Chromatography. Antiserum was first purified against the phosphorylated form of the immunizing peptide. The resultant affinity purified antibody was then cross-adsorbed against the non-phosphorylated form of the immunizing peptide.
- Reactivity
- Human, Mouse, Rat, Canine, Chicken/Avian, Horse
- Host
- Rabbit
- Epitope
- Thr2609
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.93 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Submitted references DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner.
ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage.
Proteolytic cleavage of the catalytic subunit of DNA-dependent protein kinase during poliovirus infection.
Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule.
DNA-PKcs function regulated specifically by protein phosphatase 5.
DNA-dependent PK inhibits adeno-associated virus DNA integration.
Zhang S, Schlott B, Görlach M, Grosse F
Nucleic acids research 2004;32(1):1-10
Nucleic acids research 2004;32(1):1-10
ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage.
Panta GR, Kaur S, Cavin LG, Cortés ML, Mercurio F, Lothstein L, Sweatman TW, Israel M, Arsura M
Molecular and cellular biology 2004 Mar;24(5):1823-35
Molecular and cellular biology 2004 Mar;24(5):1823-35
Proteolytic cleavage of the catalytic subunit of DNA-dependent protein kinase during poliovirus infection.
Graham KL, Gustin KE, Rivera C, Kuyumcu-Martinez NM, Choe SS, Lloyd RE, Sarnow P, Utz PJ
Journal of virology 2004 Jun;78(12):6313-21
Journal of virology 2004 Jun;78(12):6313-21
Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule.
Sawchuk DJ, Mansilla-Soto J, Alarcon C, Singha NC, Langen H, Bianchi ME, Lees-Miller SP, Nussenzweig MC, Cortes P
The Journal of biological chemistry 2004 Jul 9;279(28):29821-31
The Journal of biological chemistry 2004 Jul 9;279(28):29821-31
DNA-PKcs function regulated specifically by protein phosphatase 5.
Wechsler T, Chen BP, Harper R, Morotomi-Yano K, Huang BC, Meek K, Cleaver JE, Chen DJ, Wabl M
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 3;101(5):1247-52
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 3;101(5):1247-52
DNA-dependent PK inhibits adeno-associated virus DNA integration.
Song S, Lu Y, Choi YK, Han Y, Tang Q, Zhao G, Berns KI, Flotte TR
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 17;101(7):2112-6
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 17;101(7):2112-6
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