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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
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- Product number
- ABIN268847 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) (AA 1100-1300) antibody (Biotin)
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat, Canine, Chicken/Avian, Hamster, Porcine
- Host
- Rabbit
- Conjugate
- Biotin
- Epitope
- AA 1100-1300
- Vial size
- 0.1 mL
- Storage
- Store at 4°C in the dark.
Submitted references Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR.
Ceramide enhances cholesterol efflux to apolipoprotein A-I by increasing the cell surface presence of ATP-binding cassette transporter A1.
Expression of sterol 27-hydroxylase (CYP27A1) enhances cholesterol efflux.
Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion.
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.
Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations.
T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice.
Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells.
22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.
ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.
LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells.
Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels.
Trypsin-sensitive and lipid-containing sites of the macrophage extracellular matrix bind apolipoprotein A-I and participate in ABCA1-dependent cholesterol efflux.
Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR
Journal of lipid research 2003 Sep;44(9):1728-36
Journal of lipid research 2003 Sep;44(9):1728-36
Ceramide enhances cholesterol efflux to apolipoprotein A-I by increasing the cell surface presence of ATP-binding cassette transporter A1.
Witting SR, Maiorano JN, Davidson WS
The Journal of biological chemistry 2003 Oct 10;278(41):40121-7
The Journal of biological chemistry 2003 Oct 10;278(41):40121-7
Expression of sterol 27-hydroxylase (CYP27A1) enhances cholesterol efflux.
Escher G, Krozowski Z, Croft KD, Sviridov D
The Journal of biological chemistry 2003 Mar 28;278(13):11015-9
The Journal of biological chemistry 2003 Mar 28;278(13):11015-9
Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion.
Sun Y, Yao J, Kim TW, Tall AR
The Journal of biological chemistry 2003 Jul 25;278(30):27688-94
The Journal of biological chemistry 2003 Jul 25;278(30):27688-94
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.
Wang N, Chen W, Linsel-Nitschke P, Martinez LO, Agerholm-Larsen B, Silver DL, Tall AR
The Journal of clinical investigation 2003 Jan;111(1):99-107
The Journal of clinical investigation 2003 Jan;111(1):99-107
Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations.
Basso F, Freeman L, Knapper CL, Remaley A, Stonik J, Neufeld EB, Tansey T, Amar MJ, Fruchart-Najib J, Duverger N, Santamarina-Fojo S, Brewer HB Jr
Journal of lipid research 2003 Feb;44(2):296-302
Journal of lipid research 2003 Feb;44(2):296-302
T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice.
Terasaka N, Hiroshima A, Koieyama T, Ubukata N, Morikawa Y, Nakai D, Inaba T
FEBS letters 2003 Feb 11;536(1-3):6-11
FEBS letters 2003 Feb 11;536(1-3):6-11
Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells.
Le Lay S, Robichon C, Le Liepvre X, Dagher G, Ferre P, Dugail I
Journal of lipid research 2003 Aug;44(8):1499-507
Journal of lipid research 2003 Aug;44(8):1499-507
22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.
Koldamova RP, Lefterov IM, Ikonomovic MD, Skoko J, Lefterov PI, Isanski BA, DeKosky ST, Lazo JS
The Journal of biological chemistry 2003 Apr 11;278(15):13244-56
The Journal of biological chemistry 2003 Apr 11;278(15):13244-56
ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.
Feng B, Tabas I
The Journal of biological chemistry 2002 Nov 8;277(45):43271-80
The Journal of biological chemistry 2002 Nov 8;277(45):43271-80
LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells.
Murthy S, Born E, Mathur SN, Field FJ
Journal of lipid research 2002 Jul;43(7):1054-64
Journal of lipid research 2002 Jul;43(7):1054-64
Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels.
Fukumoto H, Deng A, Irizarry MC, Fitzgerald ML, Rebeck GW
The Journal of biological chemistry 2002 Dec 13;277(50):48508-13
The Journal of biological chemistry 2002 Dec 13;277(50):48508-13
Trypsin-sensitive and lipid-containing sites of the macrophage extracellular matrix bind apolipoprotein A-I and participate in ABCA1-dependent cholesterol efflux.
Burgess JW, Kiss RS, Zheng H, Zachariah S, Marcel YL
The Journal of biological chemistry 2002 Aug 30;277(35):31318-26
The Journal of biological chemistry 2002 Aug 30;277(35):31318-26
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