ABIN268848

antibody from antibodies-online

Targeting: ABCA1 ABC1, HDLDT1, TGD

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN268848

Provider

antibodies-online

Product name

anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) (AA 1100-1300) antibody (HRP)

Antibody type

Polyclonal

Description

Immunogen affinity purified

Reactivity

Human, Mouse, Rat, Canine, Chicken/Avian, Hamster, Porcine

Host

Rabbit

Conjugate

Horseradish Peroxidase

Epitope

AA 1100-1300

Vial size

0.1 mL

Storage

Store at 4°C in the dark.

References

Submitted references

Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR.

Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR
Journal of lipid research 2003 Sep;44(9):1728-36

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Ceramide enhances cholesterol efflux to apolipoprotein A-I by increasing the cell surface presence of ATP-binding cassette transporter A1.

Witting SR, Maiorano JN, Davidson WS
The Journal of biological chemistry 2003 Oct 10;278(41):40121-7

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Expression of sterol 27-hydroxylase (CYP27A1) enhances cholesterol efflux.

Escher G, Krozowski Z, Croft KD, Sviridov D
The Journal of biological chemistry 2003 Mar 28;278(13):11015-9

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Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion.

Sun Y, Yao J, Kim TW, Tall AR
The Journal of biological chemistry 2003 Jul 25;278(30):27688-94

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A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

Wang N, Chen W, Linsel-Nitschke P, Martinez LO, Agerholm-Larsen B, Silver DL, Tall AR
The Journal of clinical investigation 2003 Jan;111(1):99-107

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Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations.

Basso F, Freeman L, Knapper CL, Remaley A, Stonik J, Neufeld EB, Tansey T, Amar MJ, Fruchart-Najib J, Duverger N, Santamarina-Fojo S, Brewer HB Jr
Journal of lipid research 2003 Feb;44(2):296-302

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T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice.

Terasaka N, Hiroshima A, Koieyama T, Ubukata N, Morikawa Y, Nakai D, Inaba T
FEBS letters 2003 Feb 11;536(1-3):6-11

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Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells.

Le Lay S, Robichon C, Le Liepvre X, Dagher G, Ferre P, Dugail I
Journal of lipid research 2003 Aug;44(8):1499-507

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22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.

Koldamova RP, Lefterov IM, Ikonomovic MD, Skoko J, Lefterov PI, Isanski BA, DeKosky ST, Lazo JS
The Journal of biological chemistry 2003 Apr 11;278(15):13244-56

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ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.

Feng B, Tabas I
The Journal of biological chemistry 2002 Nov 8;277(45):43271-80

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LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells.

Murthy S, Born E, Mathur SN, Field FJ
Journal of lipid research 2002 Jul;43(7):1054-64

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Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels.

Fukumoto H, Deng A, Irizarry MC, Fitzgerald ML, Rebeck GW
The Journal of biological chemistry 2002 Dec 13;277(50):48508-13

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Trypsin-sensitive and lipid-containing sites of the macrophage extracellular matrix bind apolipoprotein A-I and participate in ABCA1-dependent cholesterol efflux.

Burgess JW, Kiss RS, Zheng H, Zachariah S, Marcel YL
The Journal of biological chemistry 2002 Aug 30;277(35):31318-26