ABIN263928

antibody from antibodies-online

Targeting: AHNAK MGC5395

Western blot (Recommended by provider)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN263928

Provider

antibodies-online

Product name

anti-AHNAK Nucleoprotein (AHNAK) (N-Term) antibody

Antibody type

Monoclonal

Description

Protein A Affinity Chromatography

Reactivity

Human, Mouse

Host

Mouse

Epitope

N-Term

Isotype

IgG

Antibody clone number

EM-09

Vial size

0.1 mg

Storage

Store the antibody at 2 - 8°C up to one month or (in aliquots) at -20 to -80°C for longer. Avoid repeated freezing and thawing.Shelf life: one year from despatch.

References

Submitted references

A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation.

Matza D, Badou A, Kobayashi KS, Goldsmith-Pestana K, Masuda Y, Komuro A, McMahon-Pratt D, Marchesi VT, Flavell RA
Immunity 2008 Jan;28(1):64-74

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Ahnak is critical for cardiac Ca(V)1.2 calcium channel function and its beta-adrenergic regulation.

Haase H, Alvarez J, Petzhold D, Doller A, Behlke J, Erdmann J, Hetzer R, Regitz-Zagrosek V, Vassort G, Morano I
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 Dec;19(14):1969-77

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Protein kinase B phosphorylates AHNAK and regulates its subcellular localization.

Sussman J, Stokoe D, Ossina N, Shtivelman E
The Journal of cell biology 2001 Sep 3;154(5):1019-30

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The giant protein AHNAK is a specific target for the calcium- and zinc-binding S100B protein: potential implications for Ca2+ homeostasis regulation by S100B.

Gentil BJ, Delphin C, Mbele GO, Deloulme JC, Ferro M, Garin J, Baudier J
The Journal of biological chemistry 2001 Jun 29;276(26):23253-61