323207

antibody from BioLegend
Targeting: ENG CD105, END, HHT1, ORW, ORW1
Provider product page for 323207

Antibody data

Product number
323207 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#323207, RRID:AB_755959
Product name
APC anti-human CD105
Antibody type
Monoclonal
Antigen
L-cells transfected with human CD105
Description
CD105 is also known as Endoglin. It is a type I integral membrane homodimer protein with subunits of 90 kD found on vascular endothelial cells and syncytiotrophoblasts of placenta. CD105 is weakly expressed on stromal fibroblasts. It is also expressed on activated monocytes and tissue macrophages. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation. CD105 is a component of the TGF-β receptor system in human umbilical vein endothelial cells and binds TGF-β1 and β3 with high affinity but does not bind to TGF-β2.
Reactivity
Human
Host
Mouse
Conjugate
Red dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
ENG protein structure - 323207 shown in red.