Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
Reference
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- Product number
- 325602 - Provider product page

- Provider
- BioLegend
- Proper citation
- BioLegend Cat#325602, RRID:AB_830675
- Product name
- Purified anti-human CD14
- Antibody type
- Monoclonal
- Antigen
- CD14
- Description
- CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokines expression in monocytes and neutrophils.
- Reactivity
- Human, Horse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes.
Santer DM, Wiedeman AE, Teal TH, Ghosh P, Elkon KB
Journal of immunology (Baltimore, Md. : 1950) 2012 Jan 15;188(2):902-15
Journal of immunology (Baltimore, Md. : 1950) 2012 Jan 15;188(2):902-15
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral blood monocytes stained with purified HCD14, followed by anti-mouse IgG FITC
- Conjugate
- Unconjugated