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Learn505904
antibody from BioLegend
Targeting: CCL2
GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [0]
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- Validations
- Flow cytometry [1]
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- Product number
- 505904 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#505904, RRID:AB_315410
- Product name
- PE anti-mouse/rat/human MCP-1
- Antibody type
- Monoclonal
- Antigen
- CHO-expressed, recombinant mouse MCP-1
- Description
- Monocyte chemotactic protein-1 (MCP-1) also known as monocyte chemotactic and activating factor (MCAF) was identified based on its ability to chemoattract monocytes. Subsequently, MCP-1 has also been found to regulate adhesion molecule expression and cytokine production in monocytes. MCP-1 is identical to the product of the JE gene, a PDGF inducible gene. MCP-1 is a member of the beta (C-C) chemokine subfamily, known as CCL2. The 2H5 antibody reacts with mouse, rat, and human MCP-1. The 2H5 antibody can neutralize the bioactivity of natural or recombinant MCP-1.
- Reactivity
- Human, Mouse, Rat
- Host
- Hamster
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.2 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- LPS-stimulated human peripheral blood monocytes were surface stained with CD14 FITC and then intracellular stained with 2H5 PE
- Conjugate
- Yellow dye
