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- References [252]
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- Product number
- 21923-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21923-1-AP, RRID:AB_11042445
- Product name
- ACC1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ACC1 antibody (Cat. #21923-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NUDT7 Modulates the UBA52-SREBF1 Signaling Axis to Promote PRRSV Replication via Lipid Synthesis.
Chronic intermittent hypoxia increases Parkinson's disease susceptibility via PPARα-mediated lipid droplet-mitochondrial dysfunction.
The D826V point mutation in IREB2 induces lipogenesis in adipose tissues.
Hepatic IFRD1 suppresses metabolic dysfunction-associated fatty liver disease via GLUD1/α-KG axis.
Apocrine carcinoma of the breast: distinctive metabolic reprogramming and high-frequency PIK3CA mutations revealed by molecular and immunohistochemical analysis.
ANXA1 overexpression promotes B cell acute lymphoblastic leukemia progression and resistance by regulating fatty acid metabolism through PI3K/Akt signaling.
Effects of dietary tributyrin on quality of breast meat in heat-stressed Taihe silky fowls.
Integrated Proteomics and Metabolomics Reveal the Direct Hepatic Protection of Propionate Against Alcoholic Liver Disease via the RGN-PPARα Pathway.
Asymmetric dimethylguanidino valeric acid as an independently associated risk factor for early hypertriglyceridemia and dyslipidemia.
Integrated Multiomic Analysis Provides New Insights into the Adipogenic Differentiation of Porcine Adipocytes and Reveals the Regulatory Role of ACACA in Adipogenesis.
ZXDB Drives Macrophage Inflammatory Programming in Sepsis-Induced Acute Kidney Injury by Recruiting EIF4A3 to Enhance ACACA Translation.
Integrating multi-omics approaches to elucidate the mechanism of XiaoPi Decoction in treating hyperplasia of mammary glands via AMPK signaling pathway activation.
Costunolide Ameliorates Hepatic Steatosis and Insulin Resistance in a Diet-Induced Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease by Activating the AMPK/ACC1 Signalling Pathway.
Total Extract of Folium Rhododendri Daurici alleviate MASLD by regulating PPAR and TNF signaling pathways.
cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation.
Monascus pilosus SWM-008-Fermented Red Mold Rice and Its Monascinol Ameliorate Non-Alcoholic Fatty Liver Disease via Activation of the AMPK-ATGL Pathway and Enrichment of Butyrate-Producing Bacteria.
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy.
Narirutin Reprograms Fatty Acid Metabolism and Inhibits Tumorigenesis via Downregulating ADORA3 Expression in Colorectal Cancer.
ND-630, an acetyl-CoA carboxylase inhibitor, prevents renal fibrosis in adenine-induced CKD mice.
Targeting aldose reductase in pulmonary fibrosis: Blocking de novo fatty acid synthesis halts pro-fibrotic M2 polarization.
Unraveling COPD pathogenesis: a multi-omics approach to identify metabolites and genetic links.
The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis.
High-fat diet mediates the formation of nonalcoholic fatty liver by modulating the AhR/miR-132/SIRT1 axis.
Lysine malonylation regulates human sperm motility.
FOXA3 Alleviates Lipid Deposition in Primary Bovine Hepatocytes by Inhibiting SREBP1 and Cell Proliferation.
Paeoniflorin Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease by Inhibiting Hepatic Lipogenesis and Inflammation.
Macrophage-derived IL-6 reprograms lipid metabolism to promote colorectal cancer development through USP14-mediated FASN deubiquitination.
Bench-to-Bedside Evaluation of Sulforaphane/BroccoMax® on Fatty Acid Synthesis in Prostate Cancer.
Erianin inhibits 3T3-L1 adipocyte differentiation through downregulation of CCAAT-enhancer binding protein-α and peroxisome proliferator-activated receptor-γ, lipogenic genes and impairment of mitochondrial respiration.
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis.
The tumor suppressor NDRG2 promotes ACC1 proteasomal degradation and inhibits de novo lipogenesis in hepatocellular carcinoma.
Dapagliflozin induces renal lipidomic remodeling and systemic metabolic improvement.
1-O-acetylbritannilactone alleviates high-fat diet-induced fatty liver by covalently targeting NLRP3.
Effects of different pre-conditioning exercise on leptin synthesis and its downstream signalling pathway in T2DM rats.
FOXK2 regulates fatty acid metabolism and promotes cervical cancer progression by activating the mTOR/DRP1 signaling axis.
Matrix stiffness boosts PDAC chemoresistance via SCD1-dependent lipid metabolic reprogramming.
Comparative effects of different loads of aerobic exercise on lipid metabolism in MASLD rats: a perspective from the gut-liver axis.
Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis.
Acetyl-CoA carboxylase activation disrupts iron homeostasis to drive ferroptosis.
Choline reduces inflammatory response and lipid accumulation in calf hepatocytes induced by NEFA via inhibiting ROS/ NF-κB/NLRP3 inflammasome axis.
Klebsiella pneumoniae Induces Ferroptosis and Lactation Dysfunction in Bovine Mastitis via NCOA4-Mediated Ferritinophagy.
Saponin from Tea (Camellia sinensis) Seed Meal Attenuates Cortisol-Induced Lipogenesis and Inflammation in Human Cells.
Breviscapine regulates lipid metabolism of microglia via the ADORA1/PPARα/ACOX1 pathway to promote spinal cord injury recovery.
Enhanced bioactivity of honeysuckle-Cassia seeds extracts through Lactobacillus acidophilus and Bacillus subtilis co-fermentation: Impact on alcoholic liver disease and gut microbiota.
Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation.
Triclocarban Disrupts Hepatic Lipid Homeostasis and Promotes Endoplasmic Reticulum Stress in Mice: A Multiomics Investigation.
Codonopsis pilosula polysaccharides attenuate lipid accumulation and inflammatory response in the NAFLD mouse by regulating AMPK/ACC/SREBP1 signaling pathway.
Network pharmacology and transcriptomics reveal complanatoside A regulates lipid metabolism in hyperlipidemia and nonalcoholic fatty liver disease via the AMPK pathway.
Jianpi Qutan Decoction improves hepatic lipid metabolism in atherosclerosis mice via PPARα-CPT1α pathway regulation.
Downregulation of acetyl-CoA carboxylase induces ferroptosis and inhibits tumor growth in oral squamous cell carcinoma.
Divergent Regulation of Mammary Lipogenesis by trans-10, cis-12 and cis-9, trans-11 CLA Isomers Is Determined by Receptor-Specific Signaling.
Pharmacological induction of acetyl-CoA carboxylase 1 autophagic degradation attenuates lipid accumulation and cholangiocarcinoma progression.
Unveiling plumbagin as a novel metabolic modulator to suppress ACC1-mediated de novo lipogenesis in non-small cell lung cancer.
Roseburia hominis enriched by baicalin reverses the non-response to metformin via upregulating linolenic acid metabolism.
The cyclic peptide mallotumide A inhibits colon and breast cancer cell growth and motility by targeting cellular respiration and lipogenesis.
Radix Rehmanniae Praeparata Extract Enhances Liver Regeneration Through AMPK-Driven Metabolic Reprogramming.
RNF180 suppressed aggressiveness by degrading NOTCH1, TRIM24 and FOXC1, and chemoresistance by degrading ACC1 and ACLY in colorectal cancer.
ARMC10 Drives Glioblastoma Progression Through Activating Notch Pathway.
AMPKα alleviates the inhibitory effect of NEFA on the function of bovine follicular granulosa cells cultured in vitro.
FTO aggravates podocyte injury and diabetic nephropathy progression via m6A-dependent stabilization of ACC1 mRNA and promoting fatty acid metabolism.
Steam explosion modified pea peptides alleviates hepatosteatosis by regulating lipid metabolism pathways and promoting autophagy.
Hepatic AKAP1 deficiency exacerbates diet-induced MASLD by enhancing GPAT1-mediated lysophosphatidic acid synthesis.
Comparative Analysis of Proteomic Characteristics in Seminal Plasma Between Horses and Donkeys.
Sex-dependent adaptations in heart mitochondria from transgenic mice overexpressing cytochrome b(5) reductase-3.
Mutations in the kinesin KIF12 promote MASH in humans and mice by disrupting lipogenic enzyme turnover.
Structural characterization of polysaccharides from Polygonatum Sibiricum and effect on alleviating hyperlipidemia in egg yolk emulsion-induced mice.
Exogenous hydrogen sulfide improves non-alcoholic fatty liver disease by inhibiting endoplasmic reticulum stress/NLRP3 inflammasome pathway.
Ginsenoside Rk1 Ameliorates Non-Alcoholic Fatty Liver Disease by Targeting CD36 to Modulate the AMPK Signaling Pathway.
Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway.
Hawthorn total flavonoids ameliorate hyperlipidemia through AMPK/SREBP1-c and PPARα/PGC-1α/CPT-1A pathway activation and gut microbiota modulation.
Enzymatic Synthesis and Evaluation of Eight Methylated Quercetin Products: In Vitro Chemical Properties and Adipogenesis Regulation.
Hypoxia ameliorates high-fat-diet-induced hepatic lipid accumulation by modulating the HIF2α/PP4C signaling.
AdipoR2 enhances adipocyte thermogenesis in Tibetan pigs via AMPK-ACC signaling.
Heat shock protein 90 chaperone activity is required for hepatitis A virus replication.
KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy.
The N-terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism.
AMPK-regulated glycerol excretion maintains metabolic crosstalk between reductive and energetic stress.
S100P is a ferroptosis suppressor to facilitate hepatocellular carcinoma development by rewiring lipid metabolism.
Network pharmacology, transcriptomics, and biological validation reveal a lipid secretion inhibitory and anti-inflammatory mechanism of tanreqing gel in the treatment of acne.
Melittin suppresses ovarian cancer growth by regulating SREBP1-mediated lipid metabolism.
Mechanism of O-GlcNAcylation regulating liver lipid synthesis in mice through FASN.
Vitisin A Outperforms Cyanidin-3-O-Glucoside in Triglyceride Reduction by Modulating Hepatic Lipogenesis and Fatty Acid β-Oxidation.
Ferulic acid from Angelica sinensis (Oliv.) Diels ameliorates lipid metabolism in alcoholic liver disease via AMPK/ACC and PI3K/AKT pathways.
IMUP promotes fatty acid metabolism and lung cancer progression by regulating TGF-β/SMAD3 signaling pathway.
Kaili sour soup in alleviation of hepatic steatosis in rats via lycopene route: an experimental study.
Dual mechanisms of Vitisin A in managing alcoholic liver disease: Inhibition of lipogenesis and complement activation.
Discovery of highly potent marine-derived compound Penicolinate H reveals SREBP-1 mediated lipogenesis as a druggable vulnerability in gastric cancer.
Transcriptome analysis reveals reduced lipid accumulation and mitochondrial metabolic remodeling in ADCY3-overexpressing adipocytes.
Exosomal proteomics reveals fatty acid metabolism linked to gefitinib resistance in non-small cell lung cancer.
Collateral metabolic vulnerabilities unveiled by loss of isozyme diversity in breast cancer.
CD36-mediated fatty acid metabolic reprogramming activates synovial fibroblasts and promotes rheumatoid arthritis progression.
Biomimetic membrane-coated nanoparticles for targeted synergistic therapy of homocysteine-induced atherosclerosis: Dual modulation of cholesterol efflux and reactive oxygen species scavenging.
Dietary Branched-Chain Amino Acids Restriction in High-Fat Diet-Induced Obese Mice: Effects on Metabolic Homeostasis, Adipose Inflammation, and Gut Microbiota.
MOSPD1 facilitates fatty acid metabolism and gastric cancer progression by promoting the MAPK pathway.
IRX5 Promoted SREBP1-Mediated de Novo Fatty Acid Synthesis via HMGN4 in Hepatocellular Carcinoma.
The AKAP12-PKA axis regulates lipid homeostasis during alcohol-associated liver disease.
IGF2BP3/ESM1/KLF10/BECN1 positive feedback loop: a novel therapeutic target in ovarian cancer via lipid metabolism reprogramming.
HIIT versus MICT in MASLD: mechanisms mediated by gut-liver axis crosstalk, mitochondrial dynamics remodeling, and adipokine signaling attenuation.
Differences in Fatty Acid Metabolism between MCDD and HFD Induced Metabolic Dysfunction-associated Fatty Liver Disease Model Mice.
A Small Molecule Inhibitor of Leucine Carboxyl Methyltransferase-1 Inhibits Cancer Cell Survival.
Protective effects of small RNAs encapsulated in Artemisia Capillaris-derived exosomes against non-alcoholic fatty liver disease.
Chaihu Shugan powder restores fatty acid synthesis to alleviate insulin resistance in metabolic syndrome by regulating the LXRα/SREBP-1 signaling pathway.
Schisanhenol ameliorates non-alcoholic fatty liver disease via inhibiting miR-802 activation of AMPK-mediated modulation of hepatic lipid metabolism.
Effects of Mao tea from Nankun Mountain on nonalcoholic fatty liver disease in mice.
Augmented Global Protein Acetylation Diminishes Cell Growth and Migration of Cholangiocarcinoma Cells.
Two novel compounds inhibit Flavivirus infection in vitro and in vivo by targeting lipid metabolism.
CYB5R3 overexpression exhibits sexual dimorphism: Mitochondrial and metabolic adaptations in transgenic female mice during calorie restriction.
Sodium citrate targeting Ca(2+)/CAMKK2 pathway exhibits anti-tumor activity through inducing apoptosis and ferroptosis in ovarian cancer.
Transcriptional Regulation of De Novo Lipogenesis by SIX1 in Liver Cancer Cells.
Protective Effects of Isostrictiniin Against High-Fat, High-Sugar Diet-Induced Steatosis in MASLD Mice via Regulation of the AMPK/SREBP-1c/ACC Pathway.
NAT10 promotes liver lipogenesis in mouse through N4-acetylcytidine modification of Srebf1 and Scap mRNA.
Evaluation of hepatic AMPK, mTORC1, and autophagy-lysosomal pathway in cows with mild or moderate fatty liver.
SIRT2-mediated deacetylation of ACLY promotes the progression of oesophageal squamous cell carcinoma.
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
BNIP3 in hypoxia-induced mitophagy: Novel insights and promising target for non-alcoholic fatty liver disease.
miR-1268a Regulates Fatty Acid Metabolism by Targeting CD36 in Angiotensin II-induced Heart Failure.
Duodenal-jejunal bypass surgery activates eNOS and enhances antioxidant system by activating AMPK pathway to improve heart oxidative stress in diabetic cardiomyopathy rats.
The effect and mechanism of combined exposure of MC-LR and NaNO(2) on liver lipid metabolism.
ATR induces hepatic lipid metabolism disorder in rats by activating IRE1α/XBP1 signaling pathway.
Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats.
Prepared Radix Polygoni Multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition.
LncRNA Gm28382 promotes lipogenesis by interacting with miR-326-3p to regulate ChREBP signaling pathway in NAFLD.
Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease.
Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/3.
IL-10 protects against OPC ferroptosis by regulating lipid reactive oxygen species levels post stroke.
Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.
Ginsenoside Rg5 inhibits lipid accumulation and hepatocyte apoptosis via the Notch1 signaling pathway in NASH mice.
SHMT2 reduces fatty liver but is necessary for liver inflammation and fibrosis in mice.
Cresyl diphenyl phosphate (a novel organophosphate ester) induces hepatic steatosis by directly binding to liver X receptor α: From molecule action to risk assessment.
The facilitating effects of KRT80 on chemoresistance, lipogenesis, and invasion of esophageal cancer.
Neutrophil extracellular traps in rheumatoid arthritis: Activating fibroblast-like synoviocytes via ATP citrate lyase.
ANXA1-FPR2 axis mitigates the susceptibility to atrial fibrillation in obesity via rescuing AMPK activity in response to lipid overload.
miR-218-5p promotes hepatic lipogenesis through targeting Elovl5 in non-alcoholic fatty liver disease.
CD9 Counteracts Liver Steatosis and Mediates GCGR Agonist Hepatic Effects.
Berberine alleviates high-energy and low-protein diet-induced fatty liver hemorrhagic syndrome in laying hens: insights from microbiome and metabolomics.
Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet.
Lipid synthesis, triggered by PPARγ T166 dephosphorylation, sustains reparative function of macrophages during tissue repair.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Brexpiprazole suppresses cell proliferation and de novo lipogenesis through AMPK/SREBP1 pathway in colorectal cancer.
Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box(FBXO11) -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.
Hepatoviruses promote very-long-chain fatty acid and sphingolipid synthesis for viral RNA replication and quasi-enveloped virus release.
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.
Enhancement of PPARα-Inhibited Leucine Metabolism-Stimulated β-Casein Synthesis and Fatty Acid Synthesis in Primary Bovine Mammary Epithelial Cells.
Fructooligosaccharides attenuate non-alcoholic fatty liver disease by remodeling gut microbiota and association with lipid metabolism.
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
Diminishing acetyl-CoA carboxylase 1 attenuates CCA migration via AMPK-NF-κB-snail axis.
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
The feedback loop of AURKA/DDX5/TMEM147-AS1/let-7 drives lipophagy to induce cisplatin resistance in epithelial ovarian cancer.
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer.
Stearate-derived very long-chain fatty acids are indispensable to tumor growth.
Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in Obese Mice.
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
LncHLEF promotes hepatic lipid synthesis through miR-2188-3p/GATA6 axis and encoding peptides and enhances intramuscular fat deposition via exosome.
17β-Estradiol (E(2)) Upregulates the ERα/SIRT1/PGC-1α Signaling Pathway and Protects Mitochondrial Function to Prevent Bilateral Oophorectomy (OVX)-Induced Nonalcoholic Fatty Liver Disease (NAFLD).
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic FXR-SHP-SREBP1C/PPARα/CD36 pathway.
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice.
Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice.
Dysregulated autophagic activity induced in response to chronic intermittent hypoxia contributes to the pathogenesis of NAFLD.
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours.
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.
ASC Regulates Subcutaneous Adipose Tissue Lipogenesis and Lipolysis via p53/AMPKα Axis.
Upregulation of Superenhancer-Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma.
circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells.
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Paired related homeobox 1 attenuates autophagy via acetyl-CoA carboxylase 1-regulated fatty acid metabolism in salivary adenoid cystic carcinoma.
TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis.
Balanced branched-chain amino acids modulate meat quality by adjusting muscle fiber type conversion and intramuscular fat deposition in finishing pigs.
Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway.
STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway.
Ginsenoside CK ameliorates hepatic lipid accumulation via activating the LKB1/AMPK pathway in vitro and in vivo.
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Loss of Mature Lamin A/C Triggers a Shift in Intracellular Metabolic Homeostasis via AMPKα Activation.
Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication.
Predicting Panel of Metabolism and Immune-Related Genes for the Prognosis of Human Ovarian Cancer.
Biallelic Mutations in ACACA Cause a Disruption in Lipid Homeostasis That Is Associated With Global Developmental Delay, Microcephaly, and Dysmorphic Facial Features.
The Mutual Inhibition of FoxO1 and SREBP-1c Regulated the Progression of Hepatoblastoma by Regulating Fatty Acid Metabolism.
Biological Behavior and Lipid Metabolism of Colon Cancer Cells are Regulated by a Combination of Sterol Regulatory Element-Binding Protein 1 and ATP Citrate Lyase.
The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice.
Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis.
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway.
Methionine-chelated Zn promotes anabolism by integrating mTOR signal and autophagy pathway in juvenile yellow catfish.
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Dietary Marginal and Excess Selenium Increased Triglycerides Deposition, Induced Endoplasmic Reticulum Stress and Differentially Influenced Selenoproteins Expression in the Anterior and Middle Intestines of Yellow Catfish Pelteobagrus fulvidraco.
Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway.
Different Proportions of Branched-Chain Amino Acids Modulate Lipid Metabolism in a Finishing Pig Model.
Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis.
Five-(Tetradecyloxy)-2-furoic Acid Alleviates Cholangiocarcinoma Growth by Inhibition of Cell-cycle Progression and Induction of Apoptosis.
A novel metabolic function of Myc in regulation of fatty acid synthesis in prostate cancer.
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.
Dexmedetomidine ameliorates high-fat diet-induced nonalcoholic fatty liver disease by targeting SCD1 in obesity mice.
Myostatin suppresses adipogenic differentiation and lipid accumulation by activating crosstalk between ERK1/2 and PKA signaling pathways in porcine subcutaneous preadipocytes.
Four sesquiterpene glycosides from loquat (Eriobotrya japonica) leaf ameliorates palmitic acid-induced insulin resistance and lipid accumulation in HepG2 Cells via AMPK signaling pathway.
Astragalus Polysaccharides Inhibits Tumorigenesis and Lipid Metabolism Through miR-138-5p/SIRT1/SREBP1 Pathway in Prostate Cancer.
SIK1 Regulates CRTC2-Mediated Gluconeogenesis Signaling Pathway in Human and Mouse Liver Cells.
LncRNA DNAJC3-AS1 Regulates Fatty Acid Synthase via the EGFR Pathway to Promote the Progression of Colorectal Cancer.
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice.
Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
Sex-specific metabolic responses to 6 hours of fasting during the active phase in young mice.
HOXC10 promotes proliferation and attenuates lipid accumulation of sheep bone marrow mesenchymal stem cells.
l-Theanine regulates glucose, lipid, and protein metabolism via insulin and AMP-activated protein kinase signaling pathways.
Hepatic Synaptotagmin 1 is involved in the remodelling of liver plasma- membrane lipid composition and gene expression in male Apoe-deficient mice consuming a Western diet.
Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism.
Pum2 mediates Sirt1 mRNA decay and exacerbates hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Adenovirus-mediated expression of SIK1 improves hepatic glucose and lipid metabolism in type 2 diabetes mellitus rats.
MEX3C regulates lipid metabolism to promote bladder tumorigenesis through JNK pathway.
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway.
Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival.
Gypenosides improve the intestinal microbiota of non-alcoholic fatty liver in mice and alleviate its progression.
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Berberine Inhibits Adipogenesis in Porcine Adipocytes via AMP-Activated Protein Kinase-Dependent and -Independent Mechanisms.
Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling.
Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice.
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Inhibitory effect of 17β‑estradiol on triglyceride synthesis in skeletal muscle cells is dependent on ESR1 and not ESR2.
microRNA-16-5p promotes 3T3-L1 adipocyte differentiation through regulating EPT1.
Phenethyl isothiocyanate induces IPEC-J2 cells cytotoxicity and apoptosis via S-G(2)/M phase arrest and mitochondria-mediated Bax/Bcl-2 pathway.
Fibronectin type III domain-containing protein 5 promotes proliferation and differentiation of goat adipose-derived stem cells.
Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity.
mTOR direct crosstalk with STAT5 promotes de novo lipid synthesis and induces hepatocellular carcinoma.
Data Mining and Validation of AMPK Pathway as a Novel Candidate Role Affecting Intramuscular Fat Content in Pigs.
Porphyromonas gingivalis Promotes 4-Nitroquinoline-1-Oxide-Induced Oral Carcinogenesis With an Alteration of Fatty Acid Metabolism.
Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology.
Brg1 regulates pro-lipogenic transcription by modulating SREBP activity in hepatocytes.
Hepatocyte-specific deletion of Brg1 alleviates methionine-and-choline-deficient diet (MCD) induced non-alcoholic steatohepatitis in mice.
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
N-3 polyunsaturated fatty acids ameliorate hepatic steatosis via the PPAR-α/CPT-1α pathway in a mouse model of parenteral nutrition.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
MicroRNA-130b attenuates dexamethasone-induced increase of lipid accumulation in porcine preadipocytes by suppressing PPAR-γ expression.
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
5'-AMP-activated protein kinase plays an essential role in geniposide-regulated glucose-stimulated insulin secretion in rat pancreatic INS-1 β cells.
Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation.
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Formaldehyde alters triglyceride synthesis and very low-density lipoprotein secretion in a time-dependent manner.
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Protective effects of glycyrrhizic acid from edible botanical glycyrrhiza glabra against non-alcoholic steatohepatitis in mice.
MicroRNA-24 promotes 3T3-L1 adipocyte differentiation by directly targeting the MAPK7 signaling.
Gestational dietary betaine supplementation suppresses hepatic expression of lipogenic genes in neonatal piglets through epigenetic and glucocorticoid receptor-dependent mechanisms.
HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress.
Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.
Yan Y, Li C, Zhang J, Li R, Yin B, Zhang S, Zhang Y, Zhang X, Han J, Huang J
International journal of biological sciences 2026;22(3):1590-1610
International journal of biological sciences 2026;22(3):1590-1610
Chronic intermittent hypoxia increases Parkinson's disease susceptibility via PPARα-mediated lipid droplet-mitochondrial dysfunction.
Zhai MR, Pan J, Wu ZH, He YY, Zhang KR, Ren L, Wang YR, Li YB, Gao J, Xiao L, Liu YH
Theranostics 2026;16(5):2466-2487
Theranostics 2026;16(5):2466-2487
The D826V point mutation in IREB2 induces lipogenesis in adipose tissues.
Lv Y, Wu C, Xiao J, Yang W, Wang C, Wang J, Huang J, Guo Z, Liao S
Frontiers in cell and developmental biology 2026;14:1724485
Frontiers in cell and developmental biology 2026;14:1724485
Hepatic IFRD1 suppresses metabolic dysfunction-associated fatty liver disease via GLUD1/α-KG axis.
Geng M, Meng F, Li H, Sun L, Sun X, Ding Y, Shi R, Wang Z, Huang Y, Wang J, Liu Y, Wang J, Little PJ, Xu S, Liu L, Weng J, Luo S
Science bulletin 2026 May 15;71(9):2283-2299
Science bulletin 2026 May 15;71(9):2283-2299
Apocrine carcinoma of the breast: distinctive metabolic reprogramming and high-frequency PIK3CA mutations revealed by molecular and immunohistochemical analysis.
Nakamura H, Kukita Y, Kittaka N, Kusama H, Nakayama T, Tamaki Y, Yoshida KI, Kunimasa K, Imamura F, Yagi T
Histopathology 2026 Mar;88(4):790-809
Histopathology 2026 Mar;88(4):790-809
ANXA1 overexpression promotes B cell acute lymphoblastic leukemia progression and resistance by regulating fatty acid metabolism through PI3K/Akt signaling.
Liu P, Ma D, Pan C, Kang Q, Wang Y, Zhang M, Wang J
Molecular and cellular biochemistry 2026 Mar;481(3):1401-1414
Molecular and cellular biochemistry 2026 Mar;481(3):1401-1414
Effects of dietary tributyrin on quality of breast meat in heat-stressed Taihe silky fowls.
Chen C, Qu M, Li G, Wan G, Zhang W, Liu H, Yu Y, Xu L
Poultry science 2026 Mar;105(3):106364
Poultry science 2026 Mar;105(3):106364
Integrated Proteomics and Metabolomics Reveal the Direct Hepatic Protection of Propionate Against Alcoholic Liver Disease via the RGN-PPARα Pathway.
Wang H, Liu H, Wang M, Chi T, Liu F, Qu X, Mu Y, Xu Q, Wang Q
Nutrients 2026 Mar 9;18(5)
Nutrients 2026 Mar 9;18(5)
Asymmetric dimethylguanidino valeric acid as an independently associated risk factor for early hypertriglyceridemia and dyslipidemia.
Han Y, Xiong Q, Wang J, Wang A, Chen Q, Liu Y, Cheng K
Metabolomics : Official journal of the Metabolomic Society 2026 Mar 7;22(2)
Metabolomics : Official journal of the Metabolomic Society 2026 Mar 7;22(2)
Integrated Multiomic Analysis Provides New Insights into the Adipogenic Differentiation of Porcine Adipocytes and Reveals the Regulatory Role of ACACA in Adipogenesis.
Shen J, Li S, Fu K, Zhang W, Zhu C, Wang R, Sun H, Wen B, Li M, Zhang L, Liu X, Wen Y, Liao C, Qin B, Du H, Bai Y, Hu J, Ding K, Wang L
Journal of agricultural and food chemistry 2026 Mar 4;74(8):7262-7281
Journal of agricultural and food chemistry 2026 Mar 4;74(8):7262-7281
ZXDB Drives Macrophage Inflammatory Programming in Sepsis-Induced Acute Kidney Injury by Recruiting EIF4A3 to Enhance ACACA Translation.
Wu H, Gang W, Wang L, Sun J, Li S, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71657
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71657
Integrating multi-omics approaches to elucidate the mechanism of XiaoPi Decoction in treating hyperplasia of mammary glands via AMPK signaling pathway activation.
Chen L, Hu M, Ding XQ, Chen YG, Zeng QY, Zhang Z, Wang X, Liu HT
Journal of ethnopharmacology 2026 Mar 25;359:121060
Journal of ethnopharmacology 2026 Mar 25;359:121060
Costunolide Ameliorates Hepatic Steatosis and Insulin Resistance in a Diet-Induced Mouse Model of Metabolic Dysfunction-Associated Steatotic Liver Disease by Activating the AMPK/ACC1 Signalling Pathway.
Jiang W, Ye C, Hu T, Liang J, Chen Y
Phytotherapy research : PTR 2026 Mar 17;
Phytotherapy research : PTR 2026 Mar 17;
Total Extract of Folium Rhododendri Daurici alleviate MASLD by regulating PPAR and TNF signaling pathways.
Zhang Y, Yin Z, Zhang Y, Wei Y, Zhai Y, Zhao X, Zhan B, Wang Z, Feng H
Journal of ethnopharmacology 2026 Mar 1;358:120955
Journal of ethnopharmacology 2026 Mar 1;358:120955
cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation.
Wang D, Zhou Z, Zhao Z, Liu M, Li Y, Mu L, Zhou H, Li X, Zhang F, Tian S, Zhou X, Shi Y
Free radical biology & medicine 2026 Jun;249:246-259
Free radical biology & medicine 2026 Jun;249:246-259
Monascus pilosus SWM-008-Fermented Red Mold Rice and Its Monascinol Ameliorate Non-Alcoholic Fatty Liver Disease via Activation of the AMPK-ATGL Pathway and Enrichment of Butyrate-Producing Bacteria.
Hsieh CP, Hsu YW, Pan TM, Lee CL
Molecular nutrition & food research 2026 Jan;70(1):e70342
Molecular nutrition & food research 2026 Jan;70(1):e70342
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy.
Zhang Y, Shen X, Shen Y, Wang C, Yu C, Han J, Cao S, Qian L, Ma M, Huang S, Wen W, Yin M, Lei QY
Nature 2026 Jan;649(8098):1022-1031
Nature 2026 Jan;649(8098):1022-1031
Narirutin Reprograms Fatty Acid Metabolism and Inhibits Tumorigenesis via Downregulating ADORA3 Expression in Colorectal Cancer.
Wang H, Jiang R, Liu C, Chen F
Journal of gastroenterology and hepatology 2026 Jan;41(1):202-214
Journal of gastroenterology and hepatology 2026 Jan;41(1):202-214
ND-630, an acetyl-CoA carboxylase inhibitor, prevents renal fibrosis in adenine-induced CKD mice.
Liu X, Peng Y, Wu S, Xu Y, Ye X, Lu J
Naunyn-Schmiedeberg's archives of pharmacology 2026 Jan;399(2):2593-2605
Naunyn-Schmiedeberg's archives of pharmacology 2026 Jan;399(2):2593-2605
Targeting aldose reductase in pulmonary fibrosis: Blocking de novo fatty acid synthesis halts pro-fibrotic M2 polarization.
Li J, Zhang Q, Zhao P, Mei X, Shi Y, Shao W, Yu X
International journal of biological macromolecules 2026 Jan;337(Pt 2):149590
International journal of biological macromolecules 2026 Jan;337(Pt 2):149590
Unraveling COPD pathogenesis: a multi-omics approach to identify metabolites and genetic links.
Zeng M, Liu J, Cao X, Deng X, Li W, Qiu J, Yang K, Huang Y
Scientific reports 2026 Jan 22;16(1):6013
Scientific reports 2026 Jan 22;16(1):6013
The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis.
Meng F, Du Y, Liang J, Li H, Wang J, Tang K, Kong R, Sun H, Yin T, Qin J, Yang X, Shan C, Liu M, Yang G, Zhang J, Wang Y, Zhou J, Chen Y
Nature communications 2026 Jan 20;17(1):614
Nature communications 2026 Jan 20;17(1):614
High-fat diet mediates the formation of nonalcoholic fatty liver by modulating the AhR/miR-132/SIRT1 axis.
Tao Q, Xie J, Zhou Y, Wu Y, Xia H, Wang J, Zhang C, Wei C, Jin Y
The Journal of nutritional biochemistry 2026 Feb;148:110174
The Journal of nutritional biochemistry 2026 Feb;148:110174
Lysine malonylation regulates human sperm motility.
Cheng Y, Tian Y, Chen H, Peng S, Chen Y, Peng Z, Luo T
Communications biology 2026 Feb 9;9(1):178
Communications biology 2026 Feb 9;9(1):178
FOXA3 Alleviates Lipid Deposition in Primary Bovine Hepatocytes by Inhibiting SREBP1 and Cell Proliferation.
Du X, Liu M, Lei L, Wang Y, Gao W, Du X, Song Y, Liu G, Li X, Ren T, Feng H
Veterinary sciences 2026 Feb 5;13(2)
Veterinary sciences 2026 Feb 5;13(2)
Paeoniflorin Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease by Inhibiting Hepatic Lipogenesis and Inflammation.
Wei SZ, Dong Y, Zhou HY, Yang J, Lu JF, Zhao YL, Zhao Y, Lu JF
Inflammation 2026 Feb 26;49(1)
Inflammation 2026 Feb 26;49(1)
Macrophage-derived IL-6 reprograms lipid metabolism to promote colorectal cancer development through USP14-mediated FASN deubiquitination.
Yunxin L, Xirui X, Xinyi Z, Chenjing W, Ting Z, Kanghui F, Haixia Y, Zude C, Wan H, Yubing Z, Xianjun F
Journal of translational medicine 2026 Feb 26;24(1)
Journal of translational medicine 2026 Feb 26;24(1)
Bench-to-Bedside Evaluation of Sulforaphane/BroccoMax® on Fatty Acid Synthesis in Prostate Cancer.
Hahm ER, Jacobs BL, Singh KB, Kim SH, Parikh R, Normolle DP, Dhir R, Oyebamiji T, Sun X, Liu Y, Appleman LJ, Gelhaus SL, Singh SV
Cancer prevention research (Philadelphia, Pa.) 2026 Feb 25;
Cancer prevention research (Philadelphia, Pa.) 2026 Feb 25;
Erianin inhibits 3T3-L1 adipocyte differentiation through downregulation of CCAAT-enhancer binding protein-α and peroxisome proliferator-activated receptor-γ, lipogenic genes and impairment of mitochondrial respiration.
Yimpreeda H, Laowittawat C, Siritutsoontorn S, Rojvirat P, Kumphune S, Jitrapakdee S
Adipocyte 2026 Dec;15(1):2601405
Adipocyte 2026 Dec;15(1):2601405
CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis.
Wu L, Wang J, Wang Y, Yang J, Yao Y, Wang Y, Huang D, Hu Y, Xu X, Wang R, Du W, Shi Y, Li Q, Liu L, Zhu Y, Li S, Chen FJ, Zhang X, Wang X, Guo Q, Xu L, Li P, Chen XW
Nature 2026 Apr;652(8109):471-480
Nature 2026 Apr;652(8109):471-480
The tumor suppressor NDRG2 promotes ACC1 proteasomal degradation and inhibits de novo lipogenesis in hepatocellular carcinoma.
Shi Q, Bai Y, Wang J, Ru M, Zhang K, Guo Y, Bai Z, Shen L
Molecular biomedicine 2026 Apr 17;7(1)
Molecular biomedicine 2026 Apr 17;7(1)
Dapagliflozin induces renal lipidomic remodeling and systemic metabolic improvement.
Li A, Ye Y, Tang J, Hu J, Shi M, Wu Y, Ji C, Zhang H
Biology direct 2026 Apr 17;21(1)
Biology direct 2026 Apr 17;21(1)
1-O-acetylbritannilactone alleviates high-fat diet-induced fatty liver by covalently targeting NLRP3.
Jin T, Zhao Y, Xu T, Fang Y, Cui Y, Liu W, Xiong Y, Ye J, Luo W, Hong B, Liang G, Hu X, Huang L, Wang Y
International immunopharmacology 2026 Apr 1;174:116351
International immunopharmacology 2026 Apr 1;174:116351
Effects of different pre-conditioning exercise on leptin synthesis and its downstream signalling pathway in T2DM rats.
Lin S, Hu Y, Ding S, Hu Y
Iranian journal of basic medical sciences 2025;28(1):31-37
Iranian journal of basic medical sciences 2025;28(1):31-37
FOXK2 regulates fatty acid metabolism and promotes cervical cancer progression by activating the mTOR/DRP1 signaling axis.
Liao D, Zeng S, Li C, Yao Y, Guo M, Cui Y, Huang H
Frontiers in cell and developmental biology 2025;13:1615454
Frontiers in cell and developmental biology 2025;13:1615454
Matrix stiffness boosts PDAC chemoresistance via SCD1-dependent lipid metabolic reprogramming.
Zhang X, Zhu B, Yan J, Chen X, Wu D, Wang Z, Guan X, Huang Y, Zhao Y, Yang Y, Guo Y
Regenerative biomaterials 2025;12:rbaf056
Regenerative biomaterials 2025;12:rbaf056
Comparative effects of different loads of aerobic exercise on lipid metabolism in MASLD rats: a perspective from the gut-liver axis.
Dongkun D, Qingfeng J, Chang L, Yunhua L, Jiaming S, Yufei L, Lin X
Frontiers in medicine 2025;12:1609751
Frontiers in medicine 2025;12:1609751
Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis.
Wang X, Li J, Qin R, Yin Y, Li J, Lin S, Zou X
Frontiers in molecular biosciences 2025;12:1523494
Frontiers in molecular biosciences 2025;12:1523494
Acetyl-CoA carboxylase activation disrupts iron homeostasis to drive ferroptosis.
Han Z, Han S, Fang X, Lu M, Mao Y, Shi L, Song J, Wang T, Xiao J, Xiang L, Yang C, Zhu Z, Wang Y, Feng J
Free radical biology & medicine 2025 Sep;237:110-130
Free radical biology & medicine 2025 Sep;237:110-130
Choline reduces inflammatory response and lipid accumulation in calf hepatocytes induced by NEFA via inhibiting ROS/ NF-κB/NLRP3 inflammasome axis.
Zhang R, Du X, Hu H, Chen J, Yu J, Wang L, Yao J, Liu S, Wang J, Cao Y
Molecular immunology 2025 Sep;185:116-126
Molecular immunology 2025 Sep;185:116-126
Klebsiella pneumoniae Induces Ferroptosis and Lactation Dysfunction in Bovine Mastitis via NCOA4-Mediated Ferritinophagy.
Mao P, Wang Z, Duan J, Dong P, Yuan C, Liu K, Guo L, Cui L, Dong J, Meng X, Zhu G, Li J, Wang H
Journal of agricultural and food chemistry 2025 Sep 24;73(38):24326-24342
Journal of agricultural and food chemistry 2025 Sep 24;73(38):24326-24342
Saponin from Tea (Camellia sinensis) Seed Meal Attenuates Cortisol-Induced Lipogenesis and Inflammation in Human Cells.
Li J, Zhang LY, Huang YC, Deng JM, Yu M, Zouboulis CC, Li JH, Wang GL, Wang J
Molecules (Basel, Switzerland) 2025 Sep 23;30(19)
Molecules (Basel, Switzerland) 2025 Sep 23;30(19)
Breviscapine regulates lipid metabolism of microglia via the ADORA1/PPARα/ACOX1 pathway to promote spinal cord injury recovery.
Shi F, Wang S, Wu C, Wen H, Zhou W
International immunopharmacology 2025 Sep 23;162:115145
International immunopharmacology 2025 Sep 23;162:115145
Enhanced bioactivity of honeysuckle-Cassia seeds extracts through Lactobacillus acidophilus and Bacillus subtilis co-fermentation: Impact on alcoholic liver disease and gut microbiota.
Zhou M, Zhang Y, Song Z, Tang S, Liu Z, Pang M, Zhang D, Wu X, Yu X, Wang P, Wei Y
Food chemistry 2025 Sep 15;486:144463
Food chemistry 2025 Sep 15;486:144463
Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation.
Li T, Yao Z, Huang Y, Li R, Zhang L, Chen R, Gu W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70980
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70980
Triclocarban Disrupts Hepatic Lipid Homeostasis and Promotes Endoplasmic Reticulum Stress in Mice: A Multiomics Investigation.
Song Q, Zhang R, Liu X, Ji X, Han A, He F, Ding R, Zhang H
Chemical research in toxicology 2025 Sep 15;38(9):1564-1575
Chemical research in toxicology 2025 Sep 15;38(9):1564-1575
Codonopsis pilosula polysaccharides attenuate lipid accumulation and inflammatory response in the NAFLD mouse by regulating AMPK/ACC/SREBP1 signaling pathway.
Chen Q, Lin H, Huang X, Yu W
Tissue & cell 2025 Oct;96:102984
Tissue & cell 2025 Oct;96:102984
Network pharmacology and transcriptomics reveal complanatoside A regulates lipid metabolism in hyperlipidemia and nonalcoholic fatty liver disease via the AMPK pathway.
Jiang S, Liang Z, Hua J, Li Y, Fan X, Qiao Z, Wang Z, Shen Y, Fan L, Wang J
The Journal of nutritional biochemistry 2025 Oct;144:109960
The Journal of nutritional biochemistry 2025 Oct;144:109960
Jianpi Qutan Decoction improves hepatic lipid metabolism in atherosclerosis mice via PPARα-CPT1α pathway regulation.
Gao X, Hai Y, Ma D, Liu L, Pei Y, Li J, Wang W
Hereditas 2025 Oct 15;162(1):209
Hereditas 2025 Oct 15;162(1):209
Downregulation of acetyl-CoA carboxylase induces ferroptosis and inhibits tumor growth in oral squamous cell carcinoma.
Xu Z, Jia G
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2025 Nov;100(8):451-459
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2025 Nov;100(8):451-459
Divergent Regulation of Mammary Lipogenesis by trans-10, cis-12 and cis-9, trans-11 CLA Isomers Is Determined by Receptor-Specific Signaling.
Cheng S, Zhao A, Lin X, Wang Z
Animals : an open access journal from MDPI 2025 Nov 26;15(23)
Animals : an open access journal from MDPI 2025 Nov 26;15(23)
Pharmacological induction of acetyl-CoA carboxylase 1 autophagic degradation attenuates lipid accumulation and cholangiocarcinoma progression.
Pan Y, Zhang N, Fu X, Wang X, Ma Y, Chen Q, Zhou Y, Liu H, Zhu Y, Xu L, Wang Q, Chen D, Wang Z, Wang L
Journal of experimental & clinical cancer research : CR 2025 Nov 25;44(1):310
Journal of experimental & clinical cancer research : CR 2025 Nov 25;44(1):310
Unveiling plumbagin as a novel metabolic modulator to suppress ACC1-mediated de novo lipogenesis in non-small cell lung cancer.
Deng ZH, He LJ, Wei S, Li CS, Chen Y, Ai XY, Chaotham C, Jiranusornkul S, Zhang PC, Luo Z, Xing SP, Yang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157438
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157438
Roseburia hominis enriched by baicalin reverses the non-response to metformin via upregulating linolenic acid metabolism.
Miao Z, Long J, Huang B, Yan D, Wang A
iScience 2025 Nov 21;28(11):113892
iScience 2025 Nov 21;28(11):113892
The cyclic peptide mallotumide A inhibits colon and breast cancer cell growth and motility by targeting cellular respiration and lipogenesis.
Laowittawat C, Sawektreeratana N, Katewongsa K, Payomhom P, Hongthong S, Reutrakul V, Kuhakarn C, Jitrapakdee S
Scientific reports 2025 Nov 19;15(1):40774
Scientific reports 2025 Nov 19;15(1):40774
Radix Rehmanniae Praeparata Extract Enhances Liver Regeneration Through AMPK-Driven Metabolic Reprogramming.
Li C, Zheng Q, Li F, Zhang Y, Duan S, Liu J, Han Q, Liu R
Nutrients 2025 Nov 15;17(22)
Nutrients 2025 Nov 15;17(22)
RNF180 suppressed aggressiveness by degrading NOTCH1, TRIM24 and FOXC1, and chemoresistance by degrading ACC1 and ACLY in colorectal cancer.
Li N, Zhang R, Zhao XX, Zhou L, Li YL, Cui ZG, Zheng HC
International immunopharmacology 2025 Nov 14;165:115445
International immunopharmacology 2025 Nov 14;165:115445
ARMC10 Drives Glioblastoma Progression Through Activating Notch Pathway.
Feng B, Gao T, Chen L, Xing Y
Molecular carcinogenesis 2025 May;64(5):883-896
Molecular carcinogenesis 2025 May;64(5):883-896
AMPKα alleviates the inhibitory effect of NEFA on the function of bovine follicular granulosa cells cultured in vitro.
Zhao C, Xu R, Xin S, Jiang B, Feng S, Wang X, Xia C
Animal reproduction science 2025 May;276:107831
Animal reproduction science 2025 May;276:107831
FTO aggravates podocyte injury and diabetic nephropathy progression via m6A-dependent stabilization of ACC1 mRNA and promoting fatty acid metabolism.
Chang K, Hong F, Liu H, Fang Y, Wang H, Song N, Ning Y, Lu Z, Jin S, Dai Y, Ding X
Biochemical pharmacology 2025 May;235:116819
Biochemical pharmacology 2025 May;235:116819
Steam explosion modified pea peptides alleviates hepatosteatosis by regulating lipid metabolism pathways and promoting autophagy.
Zhang J, Song L, Li T, Zhu L, Wang T, Zhao P, Ma Y, Zhao J, Huang X
Food research international (Ottawa, Ont.) 2025 May;208:116182
Food research international (Ottawa, Ont.) 2025 May;208:116182
Hepatic AKAP1 deficiency exacerbates diet-induced MASLD by enhancing GPAT1-mediated lysophosphatidic acid synthesis.
He L, She X, Guo L, Gao M, Wang S, Lu Z, Guo H, Li R, Nie Y, Xing J, Ji L
Nature communications 2025 May 8;16(1):4286
Nature communications 2025 May 8;16(1):4286
Comparative Analysis of Proteomic Characteristics in Seminal Plasma Between Horses and Donkeys.
Wen X, Ren H, He Q, Yi M, Ulaangerel T, Bou G
Animals : an open access journal from MDPI 2025 May 23;15(11)
Animals : an open access journal from MDPI 2025 May 23;15(11)
Sex-dependent adaptations in heart mitochondria from transgenic mice overexpressing cytochrome b(5) reductase-3.
Sánchez-Mendoza LM, González-Reyes JA, Rodríguez-López S, Calvo-Rubio M, Calero-Rodríguez P, de Cabo R, Burón MI, Villalba JM
Mitochondrion 2025 Mar;81:102004
Mitochondrion 2025 Mar;81:102004
Mutations in the kinesin KIF12 promote MASH in humans and mice by disrupting lipogenic enzyme turnover.
Etemad A, Tanaka Y, Wang S, Slae M, Sultan M, Elpeleg O, Hirokawa N
The EMBO journal 2025 Mar;44(6):1608-1640
The EMBO journal 2025 Mar;44(6):1608-1640
Structural characterization of polysaccharides from Polygonatum Sibiricum and effect on alleviating hyperlipidemia in egg yolk emulsion-induced mice.
Zhao L, Peng Y, Huang J, Liu N, Zou X, Li J, Fan Y, Li P, Tang L, Wang J, Zeng Y, Wu Y, Zhu G
International journal of biological macromolecules 2025 Mar;296:139808
International journal of biological macromolecules 2025 Mar;296:139808
Exogenous hydrogen sulfide improves non-alcoholic fatty liver disease by inhibiting endoplasmic reticulum stress/NLRP3 inflammasome pathway.
Fu X, Zhang Q, Chen Y, Li Y, Wang H
Molecular and cellular biochemistry 2025 Jun;480(6):3813-3839
Molecular and cellular biochemistry 2025 Jun;480(6):3813-3839
Ginsenoside Rk1 Ameliorates Non-Alcoholic Fatty Liver Disease by Targeting CD36 to Modulate the AMPK Signaling Pathway.
Wu Y, Duan Z, Qu L, Liu Y, Ma X, Fan D
Food research international (Ottawa, Ont.) 2025 Jun;211:116426
Food research international (Ottawa, Ont.) 2025 Jun;211:116426
Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway.
Chen M, Liu G, Fang Z, Gao W, Song Y, Lei L, Du X, Li X
Autophagy 2025 Jun;21(6):1316-1334
Autophagy 2025 Jun;21(6):1316-1334
Hawthorn total flavonoids ameliorate hyperlipidemia through AMPK/SREBP1-c and PPARα/PGC-1α/CPT-1A pathway activation and gut microbiota modulation.
Zheng L, Lu Z, Ma Y, Cui P, Zhang X, Gan J, Li G
Journal of the science of food and agriculture 2025 Jun;105(8):4326-4337
Journal of the science of food and agriculture 2025 Jun;105(8):4326-4337
Enzymatic Synthesis and Evaluation of Eight Methylated Quercetin Products: In Vitro Chemical Properties and Adipogenesis Regulation.
Ang B, Yang T, Jiang H, Cheng Y, Chen Y, Qie X, Yin L, Wang T, Chen Q, Wang Z, Zeng M, Adhikari B, He Z, Chen J
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13973-13984
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13973-13984
Hypoxia ameliorates high-fat-diet-induced hepatic lipid accumulation by modulating the HIF2α/PP4C signaling.
Liu Z, Hou J, Tian M, Zhang Y, Huang D, Zhao N, Ma Y, Cui S
Cellular signalling 2025 Jul;131:111751
Cellular signalling 2025 Jul;131:111751
AdipoR2 enhances adipocyte thermogenesis in Tibetan pigs via AMPK-ACC signaling.
Liu S, Yang Z, Yang Y, Cai Y, Zhao S
Journal of thermal biology 2025 Jul;131:104209
Journal of thermal biology 2025 Jul;131:104209
Heat shock protein 90 chaperone activity is required for hepatitis A virus replication.
Li Y, Zheng X, Xie L, Kapustina M, Shirasaki T, Yonish B, Chen X, Hirai-Yuki A, Nagata N, Suzuki R, Isogawa M, Vogt MR, Muramatsu M, Lemon SM
Journal of virology 2025 Jul 22;99(7):e0050225
Journal of virology 2025 Jul 22;99(7):e0050225
KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy.
Guo J, Li N, Liu Q, Hao Z, Zhu G, Wang X, Wang H, Pan Q, Xu B, Han Y, Zhang G, Lian Y, Zhang W, Gu Y, Lin N, Zeng X, Jin Z, Lan W, Jiang J, Gao D, Dong L, Yuan H, Liang C, Qin J
Cancer cell 2025 Jul 14;43(7):1261-1278.e10
Cancer cell 2025 Jul 14;43(7):1261-1278.e10
The N-terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism.
Wang X, Ning C, Cheng X, Wu Z, Wu D, Ding X, Ju C, Zhou Z, Wan L, Zhao W, Shi P
Animal models and experimental medicine 2025 Jan;8(1):114-125
Animal models and experimental medicine 2025 Jan;8(1):114-125
AMPK-regulated glycerol excretion maintains metabolic crosstalk between reductive and energetic stress.
Zhai X, Yang R, Chu Q, Guo Z, Hou P, Li X, Bai C, Lu Z, Qiao L, Fu Y, Niu J, Li B
Nature cell biology 2025 Jan;27(1):141-153
Nature cell biology 2025 Jan;27(1):141-153
S100P is a ferroptosis suppressor to facilitate hepatocellular carcinoma development by rewiring lipid metabolism.
Yang M, Cui W, Lv X, Xiong G, Sun C, Xuan H, Ma W, Cui X, Cheng Y, Han L, Chu B
Nature communications 2025 Jan 8;16(1):509
Nature communications 2025 Jan 8;16(1):509
Network pharmacology, transcriptomics, and biological validation reveal a lipid secretion inhibitory and anti-inflammatory mechanism of tanreqing gel in the treatment of acne.
Ren X, Zhou N, Li D, Li L, Wang Y, Li L, Ma Y, Gao X, Zhao Y, Sun Y, Wang Y
Journal of ethnopharmacology 2025 Jan 31;340:119278
Journal of ethnopharmacology 2025 Jan 31;340:119278
Melittin suppresses ovarian cancer growth by regulating SREBP1-mediated lipid metabolism.
Wu R, Li N, Huang W, Yang Y, Zang R, Song H, Shi J, Zhu S, Liu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156367
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156367
Mechanism of O-GlcNAcylation regulating liver lipid synthesis in mice through FASN.
Li X, Zhang Z, Zhang M, Cao Y, Zhou W, Kou L, Guo W, Zhang B, Li S, Xu B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Feb 28;39(4):e70359
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Feb 28;39(4):e70359
Vitisin A Outperforms Cyanidin-3-O-Glucoside in Triglyceride Reduction by Modulating Hepatic Lipogenesis and Fatty Acid β-Oxidation.
Li Y, Li X, Liu J, Jayavanth P, Bai W, Jiao R
International journal of molecular sciences 2025 Feb 11;26(4)
International journal of molecular sciences 2025 Feb 11;26(4)
Ferulic acid from Angelica sinensis (Oliv.) Diels ameliorates lipid metabolism in alcoholic liver disease via AMPK/ACC and PI3K/AKT pathways.
Lu J, Wang C
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119118
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119118
IMUP promotes fatty acid metabolism and lung cancer progression by regulating TGF-β/SMAD3 signaling pathway.
Wu S, Liu F, Yao X, Lei Y, Wang W
Tissue & cell 2025 Dec;97:103061
Tissue & cell 2025 Dec;97:103061
Kaili sour soup in alleviation of hepatic steatosis in rats via lycopene route: an experimental study.
Li Y, Cong S, Chen R, Tang J, Zhai L, Liu Y
Annals of medicine 2025 Dec;57(1):2479585
Annals of medicine 2025 Dec;57(1):2479585
Dual mechanisms of Vitisin A in managing alcoholic liver disease: Inhibition of lipogenesis and complement activation.
Zhu Y, Deng H, Liu J, Li X, Huang X, Che Z, Bai W, Jiao R
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Dec;206:115639
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Dec;206:115639
Discovery of highly potent marine-derived compound Penicolinate H reveals SREBP-1 mediated lipogenesis as a druggable vulnerability in gastric cancer.
Chen J, Cui H, Wang X, Zeng Y, Pan D, Chen J, Zhang Z, An Y, Gu Z, Cai G, Wang H, Yu M, Yang B, Zhou S, Tan J, Liu L, Wang J, Li J, Han F
Journal of translational medicine 2025 Dec 9;23(1):1390
Journal of translational medicine 2025 Dec 9;23(1):1390
Transcriptome analysis reveals reduced lipid accumulation and mitochondrial metabolic remodeling in ADCY3-overexpressing adipocytes.
Liu L, Cui H, Xiang Z, Dong N, Niu D
Functional & integrative genomics 2025 Dec 6;25(1):266
Functional & integrative genomics 2025 Dec 6;25(1):266
Exosomal proteomics reveals fatty acid metabolism linked to gefitinib resistance in non-small cell lung cancer.
Zhang Y, Zhu W, Zhu J, Hu R, Yang Y
Cell biology and toxicology 2025 Dec 19;42(1):3
Cell biology and toxicology 2025 Dec 19;42(1):3
Collateral metabolic vulnerabilities unveiled by loss of isozyme diversity in breast cancer.
Ding R, Yu TJ, Jiang YZ, Xiao Y, Shao ZM
Genome medicine 2025 Dec 12;18(1):7
Genome medicine 2025 Dec 12;18(1):7
CD36-mediated fatty acid metabolic reprogramming activates synovial fibroblasts and promotes rheumatoid arthritis progression.
Hao J, Zheng J, Liu C, Lu J, Tan M, Li J, Mao J, Yu Y, Wang H, Zhang Y, Shen H
International immunopharmacology 2025 Dec 10;167:115594
International immunopharmacology 2025 Dec 10;167:115594
Biomimetic membrane-coated nanoparticles for targeted synergistic therapy of homocysteine-induced atherosclerosis: Dual modulation of cholesterol efflux and reactive oxygen species scavenging.
Ding H, Liu Y, Xia T, Zhang H, Hao Y, Liu B, Jiang Y
Materials today. Bio 2025 Aug;33:101938
Materials today. Bio 2025 Aug;33:101938
Dietary Branched-Chain Amino Acids Restriction in High-Fat Diet-Induced Obese Mice: Effects on Metabolic Homeostasis, Adipose Inflammation, and Gut Microbiota.
Zhang L, Xu Z, Qin S, Liu R
The Journal of nutrition 2025 Aug;155(8):2700-2710
The Journal of nutrition 2025 Aug;155(8):2700-2710
MOSPD1 facilitates fatty acid metabolism and gastric cancer progression by promoting the MAPK pathway.
Wang C, Qiu Y, Zheng X, Chen S, He C
Tissue & cell 2025 Apr;93:102752
Tissue & cell 2025 Apr;93:102752
IRX5 Promoted SREBP1-Mediated de Novo Fatty Acid Synthesis via HMGN4 in Hepatocellular Carcinoma.
Zhu L, Xu Y, Huang C, Li C, Zhang Y, Li X, Pan W, Zeng Z
Journal of cellular and molecular medicine 2025 Apr;29(7):e70441
Journal of cellular and molecular medicine 2025 Apr;29(7):e70441
The AKAP12-PKA axis regulates lipid homeostasis during alcohol-associated liver disease.
Thimme Gowda C, Siraganahalli Eshwaraiah M, Wang J, Lim Y, Tomasi ML, Mavila N, Ramani K
Signal transduction and targeted therapy 2025 Apr 9;10(1):109
Signal transduction and targeted therapy 2025 Apr 9;10(1):109
IGF2BP3/ESM1/KLF10/BECN1 positive feedback loop: a novel therapeutic target in ovarian cancer via lipid metabolism reprogramming.
Gao A, Zou J, Zeng T, Qin M, Tang X, Yi T, Song G, Zhong J, Zeng Y, Zhou W, Gao Q, Zhang Q, Zhang J, Li Y
Cell death & disease 2025 Apr 17;16(1):308
Cell death & disease 2025 Apr 17;16(1):308
HIIT versus MICT in MASLD: mechanisms mediated by gut-liver axis crosstalk, mitochondrial dynamics remodeling, and adipokine signaling attenuation.
Deng D, Xu L, Liu Y, Li C, Jiang Q, Shi J, Feng S, Lin Y
Lipids in health and disease 2025 Apr 16;24(1):144
Lipids in health and disease 2025 Apr 16;24(1):144
Differences in Fatty Acid Metabolism between MCDD and HFD Induced Metabolic Dysfunction-associated Fatty Liver Disease Model Mice.
Wang JX, Liu XZ, Guo Z, Zhang HL, Qi L, Liu J, Liu P, Xie GX, Wang XN
Biological procedures online 2025 Apr 14;27(1):14
Biological procedures online 2025 Apr 14;27(1):14
A Small Molecule Inhibitor of Leucine Carboxyl Methyltransferase-1 Inhibits Cancer Cell Survival.
Arosarena OA, Saribas AS, Papadopoulos EP
Frontiers in drug discovery 2024;4
Frontiers in drug discovery 2024;4
Protective effects of small RNAs encapsulated in Artemisia Capillaris-derived exosomes against non-alcoholic fatty liver disease.
Xu M, Ma L, Liang H, Tang W, Gu S
Frontiers in pharmacology 2024;15:1476820
Frontiers in pharmacology 2024;15:1476820
Chaihu Shugan powder restores fatty acid synthesis to alleviate insulin resistance in metabolic syndrome by regulating the LXRα/SREBP-1 signaling pathway.
Lei S, Peng W, Wu L, Yu L, Wang M, Li Q, Deng Y, Zhao S, Huang P, Chen B
Frontiers in pharmacology 2024;15:1442279
Frontiers in pharmacology 2024;15:1442279
Schisanhenol ameliorates non-alcoholic fatty liver disease via inhibiting miR-802 activation of AMPK-mediated modulation of hepatic lipid metabolism.
Li B, Xiao Q, Zhao H, Zhang J, Yang C, Zou Y, Zhang B, Liu J, Sun H, Liu H
Acta pharmaceutica Sinica. B 2024 Sep;14(9):3949-3963
Acta pharmaceutica Sinica. B 2024 Sep;14(9):3949-3963
Effects of Mao tea from Nankun Mountain on nonalcoholic fatty liver disease in mice.
Zhang W, Feng L, Li P, Wang A, Dai C, Qi Y, Lu J, Xu X
Food & function 2024 Sep 30;15(19):9863-9879
Food & function 2024 Sep 30;15(19):9863-9879
Augmented Global Protein Acetylation Diminishes Cell Growth and Migration of Cholangiocarcinoma Cells.
Saisomboon S, Kariya R, Mahalapbutr P, Insawang T, Sawanyawisuth K, Cha'on U, Rungrotmongkol T, Wongkham S, Jitrapakdee S, Okada S, Vaeteewoottacharn K
International journal of molecular sciences 2024 Sep 22;25(18)
International journal of molecular sciences 2024 Sep 22;25(18)
Two novel compounds inhibit Flavivirus infection in vitro and in vivo by targeting lipid metabolism.
Zhou J-f, Zhang M-r, Wang Q, Li M-z, Bai J-s, Dai Q, Zhang Y-h, Yan M-x, Li X-h, Chen J, Liu Y-y, Liu C-c, Ye J, Zhou B
Journal of virology 2024 Sep 17;98(9):e0063524
Journal of virology 2024 Sep 17;98(9):e0063524
CYB5R3 overexpression exhibits sexual dimorphism: Mitochondrial and metabolic adaptations in transgenic female mice during calorie restriction.
Sánchez-Mendoza LM, Pérez-Sánchez C, García-Caballero C, Pérez-Rodríguez M, Calero-Rodríguez P, Vellón-García B, Moreno JA, Burón MI, de Cabo R, González-Reyes JA, Villalba JM
Free radical biology & medicine 2024 Oct;223:69-86
Free radical biology & medicine 2024 Oct;223:69-86
Sodium citrate targeting Ca(2+)/CAMKK2 pathway exhibits anti-tumor activity through inducing apoptosis and ferroptosis in ovarian cancer.
Wu Y, Jia C, Liu W, Zhan W, Chen Y, Lu J, Bao Y, Wang S, Yu C, Zheng L, Sun L, Song Z
Journal of advanced research 2024 Nov;65:89-104
Journal of advanced research 2024 Nov;65:89-104
Transcriptional Regulation of De Novo Lipogenesis by SIX1 in Liver Cancer Cells.
Li L, Zhang X, Xu G, Xue R, Li S, Wu S, Yang Y, Lin Y, Lin J, Liu G, Gao S, Zhang Y, Ye Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2404229
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2404229
Protective Effects of Isostrictiniin Against High-Fat, High-Sugar Diet-Induced Steatosis in MASLD Mice via Regulation of the AMPK/SREBP-1c/ACC Pathway.
Yan Q, Li C, Li J, Yao Y, Zhao J
Nutrients 2024 Nov 13;16(22)
Nutrients 2024 Nov 13;16(22)
NAT10 promotes liver lipogenesis in mouse through N4-acetylcytidine modification of Srebf1 and Scap mRNA.
Wang Z, Wan X, Khan MA, Peng L, Sun X, Yi X, Chen K
Lipids in health and disease 2024 Nov 11;23(1):368
Lipids in health and disease 2024 Nov 11;23(1):368
Evaluation of hepatic AMPK, mTORC1, and autophagy-lysosomal pathway in cows with mild or moderate fatty liver.
Du X, Chen M, Fang Z, Shao Q, Yu H, Hao X, Gao X, Ju L, Li C, Yang Y, Song Y, Lei L, Liu G, Li X
Journal of dairy science 2024 May;107(5):3269-3279
Journal of dairy science 2024 May;107(5):3269-3279
SIRT2-mediated deacetylation of ACLY promotes the progression of oesophageal squamous cell carcinoma.
Zhang X, Xu Y, Li S, Qin Y, Zhu G, Zhang Q, Zhang Y, Guan F, Fan T, Liu H
Journal of cellular and molecular medicine 2024 Mar;28(6):e18129
Journal of cellular and molecular medicine 2024 Mar;28(6):e18129
The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions.
Jia C, Wu Y, Gao F, Liu W, Li N, Chen Y, Sun L, Wang S, Yu C, Bao Y, Song Z
Free radical biology & medicine 2024 Mar;214:2-18
Free radical biology & medicine 2024 Mar;214:2-18
BNIP3 in hypoxia-induced mitophagy: Novel insights and promising target for non-alcoholic fatty liver disease.
Tian M, Hou J, Liu Z, Li Z, Huang D, Zhang Y, Ma Y
The international journal of biochemistry & cell biology 2024 Mar;168:106517
The international journal of biochemistry & cell biology 2024 Mar;168:106517
miR-1268a Regulates Fatty Acid Metabolism by Targeting CD36 in Angiotensin II-induced Heart Failure.
Xu G, Xu Y, Zhang Y, Kao G, Li J
Cell biochemistry and biophysics 2024 Jun;82(2):1193-1201
Cell biochemistry and biophysics 2024 Jun;82(2):1193-1201
Duodenal-jejunal bypass surgery activates eNOS and enhances antioxidant system by activating AMPK pathway to improve heart oxidative stress in diabetic cardiomyopathy rats.
Yang G, Liu Z, Dong S, Zhao X, Ge Z, Cheng Z, Zhang X, Wang K
Journal of diabetes 2024 Jul;16(7):e13516
Journal of diabetes 2024 Jul;16(7):e13516
The effect and mechanism of combined exposure of MC-LR and NaNO(2) on liver lipid metabolism.
Yang J, Zhang Z, Du X, Wang Y, Meng R, Ge K, Wu C, Liang X, Zhang H, Guo H
Environmental research 2024 Jul 1;252(Pt 4):119113
Environmental research 2024 Jul 1;252(Pt 4):119113
ATR induces hepatic lipid metabolism disorder in rats by activating IRE1α/XBP1 signaling pathway.
Qian H, Zhao Y, Wang Y, Zhao H, Cui J, Wang Z, Ye H, Fang X, Ge Z, Zhang Y, Ye L
Toxicology 2024 Jan;501:153696
Toxicology 2024 Jan;501:153696
Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats.
Lin H, Li J, Sun M, Wang X, Zhao J, Zhang W, Lv G, Wang Y, Lin Z
International journal of biological macromolecules 2024 Jan;256(Pt 2):128538
International journal of biological macromolecules 2024 Jan;256(Pt 2):128538
Prepared Radix Polygoni Multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition.
Huang C, Zhang Y, Xu Y, Wei S, Yang T, Wang S, Li C, Lin H, Li X, Zhao S, Zhu L, Pan W
Aging 2024 Jan 26;16(3):2362-2384
Aging 2024 Jan 26;16(3):2362-2384
LncRNA Gm28382 promotes lipogenesis by interacting with miR-326-3p to regulate ChREBP signaling pathway in NAFLD.
Yang S, Zhang Y, Zhang Y, Yin L, Han X, Zhao X, Wang N, Xu L
International immunopharmacology 2024 Jan 25;127:111444
International immunopharmacology 2024 Jan 25;127:111444
Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease.
Dong J, Chen L, Ye F, Tang J, Liu B, Lin J, Zhou PH, Lu B, Wu M, Lu JH, He JJ, Engelender S, Meng Q, Song Z, He H
Nature communications 2024 Jan 2;15(1):168
Nature communications 2024 Jan 2;15(1):168
Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/3.
Wang J, Guo Y, He Y, Qin Y, Li X, Yang L, Liu K, Xiao L
Molecular metabolism 2024 Feb;80:101882
Molecular metabolism 2024 Feb;80:101882
IL-10 protects against OPC ferroptosis by regulating lipid reactive oxygen species levels post stroke.
Wu W, Luo Z, Shen D, Lan T, Xiao Z, Liu M, Hu L, Sun T, Wang Y, Zhang JN, Zhang C, Wang P, Lu Y, Yang F, Li Q
Redox biology 2024 Feb;69:102982
Redox biology 2024 Feb;69:102982
Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.
Xu S, Kong L, Li L, Wang C, Gu J, Luo H, Meng Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930
Ginsenoside Rg5 inhibits lipid accumulation and hepatocyte apoptosis via the Notch1 signaling pathway in NASH mice.
Li N, Zhu C, Fu R, Ma X, Duan Z, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155287
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155287
SHMT2 reduces fatty liver but is necessary for liver inflammation and fibrosis in mice.
Chen G, Zhou G, Zhai L, Bao X, Tiwari N, Li J, Mottillo E, Wang J
Communications biology 2024 Feb 12;7(1):173
Communications biology 2024 Feb 12;7(1):173
Cresyl diphenyl phosphate (a novel organophosphate ester) induces hepatic steatosis by directly binding to liver X receptor α: From molecule action to risk assessment.
Liu X, Sun L, Lin Y, Du J, Yang H, Li C
Environment international 2024 Dec;194:109168
Environment international 2024 Dec;194:109168
The facilitating effects of KRT80 on chemoresistance, lipogenesis, and invasion of esophageal cancer.
Yun WJ, Li J, Yin NC, Zhang CY, Cui ZG, Zhang L, Zheng HC
Cancer biology & therapy 2024 Dec 31;25(1):2302162
Cancer biology & therapy 2024 Dec 31;25(1):2302162
Neutrophil extracellular traps in rheumatoid arthritis: Activating fibroblast-like synoviocytes via ATP citrate lyase.
Li J, Wang X, Tan M, Zheng J, Mao J, Hao J, Shen H
International immunopharmacology 2024 Dec 25;143(Pt 3):113518
International immunopharmacology 2024 Dec 25;143(Pt 3):113518
ANXA1-FPR2 axis mitigates the susceptibility to atrial fibrillation in obesity via rescuing AMPK activity in response to lipid overload.
Liu P, Wang L, Wang Y, Jin L, Gong H, Fan J, Zhang Y, Li H, Fu B, Wang Q, Fu Y, Fan B, Li X, Wang H, Qin X, Zheng Q
Cardiovascular diabetology 2024 Dec 21;23(1):452
Cardiovascular diabetology 2024 Dec 21;23(1):452
miR-218-5p promotes hepatic lipogenesis through targeting Elovl5 in non-alcoholic fatty liver disease.
Wu G, Zhang Y, Liang B, Yin L, Gao M, Zhang H, Xu Y, Han X, Qi Y, Liu F, Xu L
Biochemical pharmacology 2024 Aug;226:116411
Biochemical pharmacology 2024 Aug;226:116411
CD9 Counteracts Liver Steatosis and Mediates GCGR Agonist Hepatic Effects.
Zheng Y, Wang Y, Xiong X, Zhang L, Zhu J, Huang B, Liu X, Liu J, Zhu Z, Yang G, Qu H, Zheng H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400819
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400819
Berberine alleviates high-energy and low-protein diet-induced fatty liver hemorrhagic syndrome in laying hens: insights from microbiome and metabolomics.
Cheng X, Hu Y, Kuang J, Guo X, Cao H, Wu H, Hu G, Zhuang Y
Poultry science 2024 Aug;103(8):103968
Poultry science 2024 Aug;103(8):103968
Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet.
Zhang B, Zhao W, Song D, Lyu X
Food & function 2024 Aug 27;15(17):8759-8774
Food & function 2024 Aug 27;15(17):8759-8774
Lipid synthesis, triggered by PPARγ T166 dephosphorylation, sustains reparative function of macrophages during tissue repair.
Zuo S, Wang Y, Bao H, Zhang Z, Yang N, Jia M, Zhang Q, Jian A, Ji R, Zhang L, Lu Y, Huang Y, Shen P
Nature communications 2024 Aug 23;15(1):7269
Nature communications 2024 Aug 23;15(1):7269
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
Brexpiprazole suppresses cell proliferation and de novo lipogenesis through AMPK/SREBP1 pathway in colorectal cancer.
Li T, Liu X, Long X, Li Y, Xiang J, Lv Y, Zhao X, Shi S, Chen W
Environmental toxicology 2023 Oct;38(10):2352-2360
Environmental toxicology 2023 Oct;38(10):2352-2360
Cullin-associated and neddylation-dissociated 1 regulate reprogramming of lipid metabolism through SKP1-Cullin-1-F-box(FBXO11) -mediated heterogeneous nuclear ribonucleoprotein A2/B1 ubiquitination and promote hepatocellular carcinoma.
Zhang H, Xia P, Yang Z, Liu J, Zhu Y, Huang Z, Zhang Z, Yuan Y
Clinical and translational medicine 2023 Oct;13(10):e1443
Clinical and translational medicine 2023 Oct;13(10):e1443
Hepatoviruses promote very-long-chain fatty acid and sphingolipid synthesis for viral RNA replication and quasi-enveloped virus release.
Shiota T, Li Z, Chen GY, McKnight KL, Shirasaki T, Yonish B, Kim H, Fritch EJ, Sheahan TP, Muramatsu M, Kapustina M, Cameron CE, Li Y, Zhang Q, Lemon SM
Science advances 2023 Oct 20;9(42):eadj4198
Science advances 2023 Oct 20;9(42):eadj4198
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Song K, Sun H, Tu B, Zhou Y, Lin LC, Liu ZY, Li R, Yang JJ, Zhang Y, Zhao JY, Tao H
iScience 2023 Oct 20;26(10):107931
iScience 2023 Oct 20;26(10):107931
A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.
Lin Y, Yang M, Huang L, Yang F, Fan J, Qiang Y, Chang Y, Zhou W, Yan L, Xiong J, Ping J, Chen S, Men D, Li F
Cell reports 2023 Nov 28;42(11):113453
Cell reports 2023 Nov 28;42(11):113453
Enhancement of PPARα-Inhibited Leucine Metabolism-Stimulated β-Casein Synthesis and Fatty Acid Synthesis in Primary Bovine Mammary Epithelial Cells.
Huang J, Li J, Ning Y, Ren Y, Shao Y, Zhang H, Zong X, Shi H
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16184-16193
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16184-16193
Fructooligosaccharides attenuate non-alcoholic fatty liver disease by remodeling gut microbiota and association with lipid metabolism.
Huang X, Chen Q, Fan Y, Yang R, Gong G, Yan C, Song Y, Zhang B, Xi S, Huang Y, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114300
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114300
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
Chu Q, An J, Liu P, Song Y, Zhai X, Yang R, Niu J, Yang C, Li B
The Journal of experimental medicine 2023 Mar 6;220(3)
The Journal of experimental medicine 2023 Mar 6;220(3)
Diminishing acetyl-CoA carboxylase 1 attenuates CCA migration via AMPK-NF-κB-snail axis.
Saisomboon S, Kariya R, Boonnate P, Sawanyawisuth K, Cha'on U, Luvira V, Chamgramol Y, Pairojkul C, Seubwai W, Silsirivanit A, Wongkham S, Okada S, Jitrapakdee S, Vaeteewoottacharn K
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166694
Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166694
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
Song D, Zhang A, Hu X, Zeng M, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154861
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154861
The feedback loop of AURKA/DDX5/TMEM147-AS1/let-7 drives lipophagy to induce cisplatin resistance in epithelial ovarian cancer.
Shao Y, Li H, Wu Y, Wang X, Meng J, Hu Z, Xia L, Cao S, Tian W, Zhang Y, Feng X, Zhang X, Li Y, Yang G
Cancer letters 2023 Jul 1;565:216241
Cancer letters 2023 Jul 1;565:216241
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer.
Yang Y, Luo D, Shao Y, Shan Z, Liu Q, Weng J, He W, Zhang R, Li Q, Wang Z, Li X
Cancer communications (London, England) 2023 Jan;43(1):100-122
Cancer communications (London, England) 2023 Jan;43(1):100-122
Stearate-derived very long-chain fatty acids are indispensable to tumor growth.
Chu Q, Liu P, Song Y, Yang R, An J, Zhai X, Niu J, Yang C, Li B
The EMBO journal 2023 Jan 16;42(2):e111268
The EMBO journal 2023 Jan 16;42(2):e111268
Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in Obese Mice.
Song Z, Liu N, He Y, Chen J, Li J, Wang F, Wu Z
Inflammation 2023 Feb;46(1):404-417
Inflammation 2023 Feb;46(1):404-417
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.
Ai YL, Wang WJ, Liu FJ, Fang W, Chen HZ, Wu LZ, Hong X, Zhu Y, Zhang CX, Liu LY, Hong WB, Zhou B, Chen QT, Wu Q
Cell research 2023 Dec;33(12):904-922
Cell research 2023 Dec;33(12):904-922
Lonicerae flos polysaccharides improve nonalcoholic fatty liver disease by activating the adenosine 5'-monophosphate-activated protein kinase pathway and reshaping gut microbiota.
Han C, Li Z, Liu R, Zhao Z, Wang Y, Zuo X, Zhang Y, Geng Z, Huang H, Pan X, Li W
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
Journal of the science of food and agriculture 2023 Dec;103(15):7721-7738
LncHLEF promotes hepatic lipid synthesis through miR-2188-3p/GATA6 axis and encoding peptides and enhances intramuscular fat deposition via exosome.
Guo Y, Tian W, Wang D, Yang L, Wang Z, Wu X, Zhi Y, Zhang K, Wang Y, Li Z, Jiang R, Sun G, Li G, Tian Y, Wang H, Kang X, Liu X, Li H
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127061
International journal of biological macromolecules 2023 Dec 31;253(Pt 5):127061
17β-Estradiol (E(2)) Upregulates the ERα/SIRT1/PGC-1α Signaling Pathway and Protects Mitochondrial Function to Prevent Bilateral Oophorectomy (OVX)-Induced Nonalcoholic Fatty Liver Disease (NAFLD).
Tian Y, Hong X, Xie Y, Guo Z, Yu Q
Antioxidants (Basel, Switzerland) 2023 Dec 12;12(12)
Antioxidants (Basel, Switzerland) 2023 Dec 12;12(12)
α-Lactalbumin Peptide Asp-Gln-Trp Ameliorates Hepatic Steatosis and Oxidative Stress in Free Fatty Acids-Treated HepG2 Cells and High-Fat Diet-Induced NAFLD Mice by Activating the PPARα Pathway.
Chen H, Ma Y, Qi X, Tian J, Ma Y, Niu T
Molecular nutrition & food research 2023 Aug;67(16):e2200499
Molecular nutrition & food research 2023 Aug;67(16):e2200499
Diosgenin attenuates nonalcoholic hepatic steatosis through the hepatic FXR-SHP-SREBP1C/PPARα/CD36 pathway.
Chen S, Sun S, Feng Y, Li X, Yin G, Liang P, Yu W, Meng D, Zhang X, Liu H, Zhang F
European journal of pharmacology 2023 Aug 5;952:175808
European journal of pharmacology 2023 Aug 5;952:175808
Cordycepin reprogramming lipid metabolism to block metastasis and EMT via ERO1A/mTOR/SREBP1 axis in cholangiocarcinoma.
Zhou X, Li Y, Yang C, Chen D, Wang T, Liu T, Yan W, Su Z, Peng B, Ren X
Life sciences 2023 Aug 15;327:121698
Life sciences 2023 Aug 15;327:121698
MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice.
Wang M, Zhao M, Yu J, Xu Y, Zhang J, Liu J, Zheng Z, Ye J, Wang Z, Ye D, Feng Y, Xu S, Pan W, Wei C, Wan J
Frontiers in cardiovascular medicine 2022;9:727474
Frontiers in cardiovascular medicine 2022;9:727474
Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice.
Zuo Q, Zhang G, He L, Ma S, Ma H, Zhai J, Wang Z, Zhang T, Wang Y, Guo Y
Drug design, development and therapy 2022;16:4161-4177
Drug design, development and therapy 2022;16:4161-4177
Dysregulated autophagic activity induced in response to chronic intermittent hypoxia contributes to the pathogenesis of NAFLD.
Wang D, Si D, Li G, Ding Z, Yang X, Gao C
Frontiers in physiology 2022;13:941706
Frontiers in physiology 2022;13:941706
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Li S, Dong S, Xu Q, Shi B, Li L, Zhang W, Zhu J, Cheng Y, Zhang G, Zhong M
Frontiers in physiology 2022;13:837798
Frontiers in physiology 2022;13:837798
PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours.
Yuan HF, Zhao M, Zhao LN, Yun HL, Yang G, Geng Y, Wang YF, Zheng W, Yuan Y, Song TQ, Niu JQ, Zhang XD
Acta pharmacologica Sinica 2022 Sep;43(9):2373-2385
Acta pharmacologica Sinica 2022 Sep;43(9):2373-2385
PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.
Dai W, Xiang W, Han L, Yuan Z, Wang R, Ma Y, Yang Y, Cai S, Xu Y, Mo S, Li Q, Cai G
Cancer communications (London, England) 2022 Sep;42(9):848-867
Cancer communications (London, England) 2022 Sep;42(9):848-867
ASC Regulates Subcutaneous Adipose Tissue Lipogenesis and Lipolysis via p53/AMPKα Axis.
Chen H, Pei Q, Tao L, Xia J, Lu G, Zong Y, Xie W, Li W, Huang C, Zeng T, Yu X, Wang W, Chen G, Yang S, Cheng R, Li X
International journal of molecular sciences 2022 Sep 2;23(17)
International journal of molecular sciences 2022 Sep 2;23(17)
Upregulation of Superenhancer-Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma.
Peng JY, Cai DK, Zeng RL, Zhang CY, Li GC, Chen SF, Yuan XQ, Peng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct 28;10(1):e2204711
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct 28;10(1):e2204711
circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells.
Li Q, Yao H, Wang Y, Wu Y, Thorne RF, Zhu Y, Wu M, Liu L
Cell reports 2022 Nov 22;41(8):111707
Cell reports 2022 Nov 22;41(8):111707
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Yang R, Yang C, Ma L, Zhao Y, Guo Z, Niu J, Chu Q, Ma Y, Li B
Nature communications 2022 Nov 17;13(1):7031
Nature communications 2022 Nov 17;13(1):7031
Paired related homeobox 1 attenuates autophagy via acetyl-CoA carboxylase 1-regulated fatty acid metabolism in salivary adenoid cystic carcinoma.
Gao J, Ma K, Zhang L, Li T, Zhao B, Jiang Y
FEBS open bio 2022 May;12(5):1006-1016
FEBS open bio 2022 May;12(5):1006-1016
TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis.
Huang Q, Wu D, Zhao J, Yan Z, Chen L, Guo S, Wang D, Yuan C, Wang Y, Liu X, Xing J
The EMBO journal 2022 Jun 1;41(11):e110324
The EMBO journal 2022 Jun 1;41(11):e110324
Balanced branched-chain amino acids modulate meat quality by adjusting muscle fiber type conversion and intramuscular fat deposition in finishing pigs.
Zhang L, Li F, Guo Q, Duan Y, Wang W, Yang Y, Yin Y, Gong S, Han M, Yin Y
Journal of the science of food and agriculture 2022 Jul;102(9):3796-3807
Journal of the science of food and agriculture 2022 Jul;102(9):3796-3807
Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway.
Zhang X, Huo Z, Luan H, Huang Y, Shen Y, Sheng L, Liang J, Wu F
Phytotherapy research : PTR 2022 Jan;36(1):433-447
Phytotherapy research : PTR 2022 Jan;36(1):433-447
STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway.
Zhang Y, Xu J, Qiu Z, Guan Y, Zhang X, Zhang X, Chai D, Chen C, Hu Q, Wang W
Cancer cell international 2022 Jan 5;22(1):4
Cancer cell international 2022 Jan 5;22(1):4
Ginsenoside CK ameliorates hepatic lipid accumulation via activating the LKB1/AMPK pathway in vitro and in vivo.
Zhang J, Ma X, Fan D
Food & function 2022 Feb 7;13(3):1153-1167
Food & function 2022 Feb 7;13(3):1153-1167
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
Jin X, Li X, Li L, Zhong B, Hong Y, Niu J, Li B
The Journal of biological chemistry 2022 Dec;298(12):102587
The Journal of biological chemistry 2022 Dec;298(12):102587
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Gu X, Liu H, Luo W, Wang X, Wang H, Li L
Reproductive toxicology (Elmsford, N.Y.) 2022 Dec;114:22-31
Reproductive toxicology (Elmsford, N.Y.) 2022 Dec;114:22-31
Loss of Mature Lamin A/C Triggers a Shift in Intracellular Metabolic Homeostasis via AMPKα Activation.
Zhou Y, Yang JJ, Cheng Y, Feng GX, Yang RH, Yuan Y, Wang LY, Wang M, Kong L
Cells 2022 Dec 9;11(24)
Cells 2022 Dec 9;11(24)
Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication.
Pouikli A, Maleszewska M, Parekh S, Yang M, Nikopoulou C, Bonfiglio JJ, Mylonas C, Sandoval T, Schumacher AL, Hinze Y, Matic I, Frezza C, Tessarz P
The EMBO journal 2022 Dec 1;41(23):e111239
The EMBO journal 2022 Dec 1;41(23):e111239
Predicting Panel of Metabolism and Immune-Related Genes for the Prognosis of Human Ovarian Cancer.
Zhang L, Sun W, Ren W, Zhang J, Xu G
Frontiers in cell and developmental biology 2021;9:690542
Frontiers in cell and developmental biology 2021;9:690542
Biallelic Mutations in ACACA Cause a Disruption in Lipid Homeostasis That Is Associated With Global Developmental Delay, Microcephaly, and Dysmorphic Facial Features.
Lou X, Zhou X, Li H, Lu X, Bao X, Yang K, Liao X, Chen H, Fang H, Yang Y, Lyu J, Zheng H
Frontiers in cell and developmental biology 2021;9:618492
Frontiers in cell and developmental biology 2021;9:618492
The Mutual Inhibition of FoxO1 and SREBP-1c Regulated the Progression of Hepatoblastoma by Regulating Fatty Acid Metabolism.
Hu Y, Zai H, Jiang W, Ou Z, Yao Y, Zhu Q
Mediators of inflammation 2021;2021:5754592
Mediators of inflammation 2021;2021:5754592
Biological Behavior and Lipid Metabolism of Colon Cancer Cells are Regulated by a Combination of Sterol Regulatory Element-Binding Protein 1 and ATP Citrate Lyase.
Qiu Z, Deng W, Hong Y, Zhao L, Li M, Guan Y, Su Y, Chen C, Shi Q, Yu J, Wang W
OncoTargets and therapy 2021;14:1531-1542
OncoTargets and therapy 2021;14:1531-1542
The Effect of Ellagic Acid on Hepatic Lipid Metabolism and Antioxidant Activity in Mice.
Xu Q, Li S, Tang W, Yan J, Wei X, Zhou M, Diao H
Frontiers in physiology 2021;12:751501
Frontiers in physiology 2021;12:751501
Novel SREBP1 inhibitor cinobufotalin suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis.
Meng H, Shen M, Li J, Zhang R, Li X, Zhao L, Huang G, Liu J
European journal of pharmacology 2021 Sep 5;906:174280
European journal of pharmacology 2021 Sep 5;906:174280
Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.
Luo L, Qin B, Jiang M, Xie L, Luo Z, Guo X, Zhang J, Li X, Zhu C, Du Y, Peng L, You J
Journal of nanobiotechnology 2021 Sep 30;19(1):297
Journal of nanobiotechnology 2021 Sep 30;19(1):297
Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis.
Xing Y, Ren X, Li X, Sui L, Shi X, Sun Y, Quan C, Xiu Z, Dong Y
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Journal of agricultural and food chemistry 2021 Sep 1;69(34):9822-9836
Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis.
Yan Y, Zhou Y, Li J, Zheng Z, Hu Y, Li L, Wu W
Cell death & disease 2021 Oct 7;12(10):917
Cell death & disease 2021 Oct 7;12(10):917
Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate.
Lin L, Zeng L, Liu A, Yuan D, Peng Y, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Nutrients 2021 Nov 17;13(11)
Nutrients 2021 Nov 17;13(11)
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway.
Meng Z, Liu X, Li T, Fang T, Cheng Y, Han L, Sun B, Chen L
International immunopharmacology 2021 May;94:107492
International immunopharmacology 2021 May;94:107492
Methionine-chelated Zn promotes anabolism by integrating mTOR signal and autophagy pathway in juvenile yellow catfish.
Wu K, Chen GH, Hogstrand C, Ling SC, Wu LX, Luo Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126732
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126732
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Li C, Li L, Ali I, Kuang M, Wang X, Wang G
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
Dietary Marginal and Excess Selenium Increased Triglycerides Deposition, Induced Endoplasmic Reticulum Stress and Differentially Influenced Selenoproteins Expression in the Anterior and Middle Intestines of Yellow Catfish Pelteobagrus fulvidraco.
Zhang DG, Zhao T, Xu XJ, Lv WH, Luo Z
Antioxidants (Basel, Switzerland) 2021 Mar 29;10(4)
Antioxidants (Basel, Switzerland) 2021 Mar 29;10(4)
Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway.
Pang B, Zhang J, Zhang X, Yuan J, Shi Y, Qiao L
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):354-364
Acta biochimica et biophysica Sinica 2021 Mar 2;53(3):354-364
Different Proportions of Branched-Chain Amino Acids Modulate Lipid Metabolism in a Finishing Pig Model.
Zhang L, Li F, Guo Q, Duan Y, Wang W, Yang Y, Yin Y, Gong S, Han M, Yin Y
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7037-7048
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7037-7048
Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis.
Liu C, Zhou X, Pan Y, Liu Y, Zhang Y
BMC cancer 2021 Jun 22;21(1):722
BMC cancer 2021 Jun 22;21(1):722
Five-(Tetradecyloxy)-2-furoic Acid Alleviates Cholangiocarcinoma Growth by Inhibition of Cell-cycle Progression and Induction of Apoptosis.
Boonnate P, Kariya R, Saranaruk P, Cha'on U, Sawanyawisuth K, Jitrapakdee S, Okada S, Vaeteewoottacharn K
Anticancer research 2021 Jul;41(7):3389-3400
Anticancer research 2021 Jul;41(7):3389-3400
A novel metabolic function of Myc in regulation of fatty acid synthesis in prostate cancer.
Singh KB, Hahm ER, Kim SH, Wendell SG, Singh SV
Oncogene 2021 Jan;40(3):592-602
Oncogene 2021 Jan;40(3):592-602
Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses.
Gong X, Li T, Wan R, Sha L
International immunopharmacology 2021 Feb;91:107173
International immunopharmacology 2021 Feb;91:107173
Dexmedetomidine ameliorates high-fat diet-induced nonalcoholic fatty liver disease by targeting SCD1 in obesity mice.
Tao L, Guo X, Xu M, Wang Y, Xie W, Chen H, Ma M, Li X
Pharmacology research & perspectives 2021 Feb;9(1):e00700
Pharmacology research & perspectives 2021 Feb;9(1):e00700
Myostatin suppresses adipogenic differentiation and lipid accumulation by activating crosstalk between ERK1/2 and PKA signaling pathways in porcine subcutaneous preadipocytes.
Pan S, Zhang L, Liu Z, Xing H
Journal of animal science 2021 Dec 1;99(12)
Journal of animal science 2021 Dec 1;99(12)
Four sesquiterpene glycosides from loquat (Eriobotrya japonica) leaf ameliorates palmitic acid-induced insulin resistance and lipid accumulation in HepG2 Cells via AMPK signaling pathway.
Li J, Ding X, Jian T, Lü H, Zhao L, Li J, Liu Y, Ren B, Chen J
PeerJ 2020;8:e10413
PeerJ 2020;8:e10413
Astragalus Polysaccharides Inhibits Tumorigenesis and Lipid Metabolism Through miR-138-5p/SIRT1/SREBP1 Pathway in Prostate Cancer.
Guo S, Ma B, Jiang X, Li X, Jia Y
Frontiers in pharmacology 2020;11:598
Frontiers in pharmacology 2020;11:598
SIK1 Regulates CRTC2-Mediated Gluconeogenesis Signaling Pathway in Human and Mouse Liver Cells.
Wang C, Song D, Fu J, Wen X
Frontiers in endocrinology 2020;11:580
Frontiers in endocrinology 2020;11:580
LncRNA DNAJC3-AS1 Regulates Fatty Acid Synthase via the EGFR Pathway to Promote the Progression of Colorectal Cancer.
Tang Y, Tang R, Tang M, Huang P, Liao Z, Zhou J, Zhou L, Su M, Chen P, Jiang J, Hu Y, Zhou Y, Liao Q, Zeng Z, Xiong W, Chen J, Nie S
Frontiers in oncology 2020;10:604534
Frontiers in oncology 2020;10:604534
Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice.
Feng Z, Pang L, Chen S, Pang X, Huang Y, Qiao Q, Wang Y, Vonglorkham S, Huang Q, Lin X, Wei J
International immunopharmacology 2020 Nov;88:107003
International immunopharmacology 2020 Nov;88:107003
Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
Zhang J, Yang J, Yang N, Ma J, Lu D, Dong Y, Liang H, Liu D, Cang M
Lipids in health and disease 2020 Mar 13;19(1):39
Lipids in health and disease 2020 Mar 13;19(1):39
Sex-specific metabolic responses to 6 hours of fasting during the active phase in young mice.
Freire T, Senior AM, Perks R, Pulpitel T, Clark X, Brandon AE, Wahl D, Hatchwell L, Le Couteur DG, Cooney GJ, Larance M, Simpson SJ, Solon-Biet SM
The Journal of physiology 2020 Jun;598(11):2081-2092
The Journal of physiology 2020 Jun;598(11):2081-2092
HOXC10 promotes proliferation and attenuates lipid accumulation of sheep bone marrow mesenchymal stem cells.
Ma M, Wang C, Ao Y, He N, Hao F, Liang H, Liu D
Molecular and cellular probes 2020 Feb;49:101491
Molecular and cellular probes 2020 Feb;49:101491
l-Theanine regulates glucose, lipid, and protein metabolism via insulin and AMP-activated protein kinase signaling pathways.
Lin L, Zeng L, Liu A, Peng Y, Yuan D, Zhang S, Li Y, Chen J, Xiao W, Gong Z
Food & function 2020 Feb 26;11(2):1798-1809
Food & function 2020 Feb 26;11(2):1798-1809
Hepatic Synaptotagmin 1 is involved in the remodelling of liver plasma- membrane lipid composition and gene expression in male Apoe-deficient mice consuming a Western diet.
Sancho-Knapik S, Pastor O, Barranquero C, Herrera Marcos LV, Guillén N, Arnal C, Gascón S, Navarro MA, Rodríguez-Yoldi MJ, Busto R, Lasunción MA, Osada J
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Dec;1865(12):158790
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Dec;1865(12):158790
Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism.
Fu Y, Sun Y, Wang M, Hou Y, Huang W, Zhou D, Wang Z, Yang S, Tang W, Zhen J, Li Y, Wang X, Liu M, Zhang Y, Wang B, Liu G, Yu X, Sun J, Zhang C, Yi F
Cell metabolism 2020 Dec 1;32(6):1052-1062.e8
Cell metabolism 2020 Dec 1;32(6):1052-1062.e8
Pum2 mediates Sirt1 mRNA decay and exacerbates hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Cao Y, Liu C, Wang Q, Wang W, Tao E, Wan L
Experimental cell research 2020 Aug 1;393(1):112058
Experimental cell research 2020 Aug 1;393(1):112058
Adenovirus-mediated expression of SIK1 improves hepatic glucose and lipid metabolism in type 2 diabetes mellitus rats.
Song D, Yin L, Wang C, Wen X
PloS one 2019;14(6):e0210930
PloS one 2019;14(6):e0210930
MEX3C regulates lipid metabolism to promote bladder tumorigenesis through JNK pathway.
Chao H, Deng L, Xu F, Yu Z, Xu X, Huang J, Zeng T
OncoTargets and therapy 2019;12:3285-3294
OncoTargets and therapy 2019;12:3285-3294
Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells.
Yang N, Li C, Li H, Liu M, Cai X, Cao F, Feng Y, Li M, Wang X
Frontiers in pharmacology 2019;10:709
Frontiers in pharmacology 2019;10:709
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway.
Liu G, Kuang S, Cao R, Wang J, Peng Q, Sun C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10089-10103
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10089-10103
Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival.
Wang LW, Wang Z, Ersing I, Nobre L, Guo R, Jiang S, Trudeau S, Zhao B, Weekes MP, Gewurz BE
PLoS pathogens 2019 Sep;15(9):e1008030
PLoS pathogens 2019 Sep;15(9):e1008030
Gypenosides improve the intestinal microbiota of non-alcoholic fatty liver in mice and alleviate its progression.
Huang X, Chen W, Yan C, Yang R, Chen Q, Xu H, Huang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109258
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109258
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, Lu H, Wang L, Huang D, Sun L, Li T, He X, Zhong X, Wang J, Gao P, Smith ZJ, Jia W, Zhang H
EMBO reports 2019 Oct 4;20(10):e48115
EMBO reports 2019 Oct 4;20(10):e48115
Berberine Inhibits Adipogenesis in Porcine Adipocytes via AMP-Activated Protein Kinase-Dependent and -Independent Mechanisms.
Yang Y, Liu F, Lu R, Jia J
Lipids 2019 Nov;54(11-12):667-678
Lipids 2019 Nov;54(11-12):667-678
Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling.
Meng Z, Liu Q, Sun F, Qiao L
Lipids in health and disease 2019 Nov 4;18(1):191
Lipids in health and disease 2019 Nov 4;18(1):191
Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice.
Tao W, Sun W, Liu L, Wang G, Xiao Z, Pei X, Wang M
Marine drugs 2019 Nov 16;17(11)
Marine drugs 2019 Nov 16;17(11)
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Du Y, Hu H, Pei X, Du K, Wei T
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Inhibitory effect of 17β‑estradiol on triglyceride synthesis in skeletal muscle cells is dependent on ESR1 and not ESR2.
Liu Q, Li R, Chen G, Wang J, Hu B, Li C, Zhu X, Lu Y
Molecular medicine reports 2019 Jun;19(6):5087-5096
Molecular medicine reports 2019 Jun;19(6):5087-5096
microRNA-16-5p promotes 3T3-L1 adipocyte differentiation through regulating EPT1.
Xu J, Zhang L, Shu G, Wang B
Biochemical and biophysical research communications 2019 Jul 5;514(4):1251-1256
Biochemical and biophysical research communications 2019 Jul 5;514(4):1251-1256
Phenethyl isothiocyanate induces IPEC-J2 cells cytotoxicity and apoptosis via S-G(2)/M phase arrest and mitochondria-mediated Bax/Bcl-2 pathway.
Liu S, Zhu Y, Yan S, Xiao H, Yi J, Li R, Wu J, Wen L
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2019 Dec;226:108574
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2019 Dec;226:108574
Fibronectin type III domain-containing protein 5 promotes proliferation and differentiation of goat adipose-derived stem cells.
Dong Y, Zhang S, Tao J, Zhang X, Zhang J, Yang J, Liang H, Liu D, Cang M
Research in veterinary science 2019 Aug;125:351-359
Research in veterinary science 2019 Aug;125:351-359
Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity.
Wang H, Lin C, Yao J, Shi H, Zhang C, Wei Q, Lu Y, Chen Z, Xing G, Cao X
Cell death & disease 2019 Aug 19;10(9):627
Cell death & disease 2019 Aug 19;10(9):627
mTOR direct crosstalk with STAT5 promotes de novo lipid synthesis and induces hepatocellular carcinoma.
Li T, Weng J, Zhang Y, Liang K, Fu G, Li Y, Bai X, Gao Y
Cell death & disease 2019 Aug 14;10(8):619
Cell death & disease 2019 Aug 14;10(8):619
Data Mining and Validation of AMPK Pathway as a Novel Candidate Role Affecting Intramuscular Fat Content in Pigs.
Yao C, Pang D, Lu C, Xu A, Huang P, Ouyang H, Yu H
Animals : an open access journal from MDPI 2019 Apr 1;9(4)
Animals : an open access journal from MDPI 2019 Apr 1;9(4)
Porphyromonas gingivalis Promotes 4-Nitroquinoline-1-Oxide-Induced Oral Carcinogenesis With an Alteration of Fatty Acid Metabolism.
Wu JS, Zheng M, Zhang M, Pang X, Li L, Wang SS, Yang X, Wu JB, Tang YJ, Tang YL, Liang XH
Frontiers in microbiology 2018;9:2081
Frontiers in microbiology 2018;9:2081
Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology.
Zhang J, Zhang Q, Chen X, Liu Y, Xue J, Dahan A, Zhang H, Chai Y
Evidence-based complementary and alternative medicine : eCAM 2018;2018:6503126
Evidence-based complementary and alternative medicine : eCAM 2018;2018:6503126
Brg1 regulates pro-lipogenic transcription by modulating SREBP activity in hepatocytes.
Li N, Li M, Hong W, Shao J, Xu H, Shimano H, Lu J, Xu Y
Biochimica et biophysica acta. Molecular basis of disease 2018 Sep;1864(9 Pt B):2881-2889
Biochimica et biophysica acta. Molecular basis of disease 2018 Sep;1864(9 Pt B):2881-2889
Hepatocyte-specific deletion of Brg1 alleviates methionine-and-choline-deficient diet (MCD) induced non-alcoholic steatohepatitis in mice.
Kong M, Chen X, Xu H, Wenping, Fang M, Xu Y
Biochemical and biophysical research communications 2018 Sep 3;503(1):344-351
Biochemical and biophysical research communications 2018 Sep 3;503(1):344-351
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Qiao Y, Xu L, Tao X, Yin L, Qi Y, Xu Y, Han X, Tang Z, Ma X, Liu K, Peng J
Toxicology letters 2018 Mar 1;284:37-45
Toxicology letters 2018 Mar 1;284:37-45
N-3 polyunsaturated fatty acids ameliorate hepatic steatosis via the PPAR-α/CPT-1α pathway in a mouse model of parenteral nutrition.
Tian F, Wang J, Sun H, Yang J, Wang P, Wan S, Gao X, Zhang L, Li J, Wang X
Biochemical and biophysical research communications 2018 Jul 2;501(4):974-981
Biochemical and biophysical research communications 2018 Jul 2;501(4):974-981
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
Pan S, Jia Y, Yang X, Cai D, Liu Z, Song H, Zhao R
European journal of nutrition 2018 Apr;57(3):991-1001
European journal of nutrition 2018 Apr;57(3):991-1001
MicroRNA-130b attenuates dexamethasone-induced increase of lipid accumulation in porcine preadipocytes by suppressing PPAR-γ expression.
Pan S, Cui Y, Dong X, Zhang T, Xing H
Oncotarget 2017 Oct 20;8(50):87928-87943
Oncotarget 2017 Oct 20;8(50):87928-87943
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity.
Gao Y, Li J, Xu X, Wang S, Yang Y, Zhou J, Zhang L, Zheng F, Li X, Wang B
International journal of obesity (2005) 2017 May;41(5):729-738
International journal of obesity (2005) 2017 May;41(5):729-738
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission.
Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, Hu L, Tian S, Wu M, Hui L, Zhang H, Gao P
The EMBO journal 2017 May 15;36(10):1330-1347
The EMBO journal 2017 May 15;36(10):1330-1347
5'-AMP-activated protein kinase plays an essential role in geniposide-regulated glucose-stimulated insulin secretion in rat pancreatic INS-1 β cells.
Hao Y, Liu C, Yin F, Zhang Y, Liu J
Journal of natural medicines 2017 Jan;71(1):123-130
Journal of natural medicines 2017 Jan;71(1):123-130
Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation.
Meng Q, Duan XP, Wang CY, Liu ZH, Sun PY, Huo XK, Sun HJ, Peng JY, Liu KX
Acta pharmacologica Sinica 2017 Jan;38(1):69-79
Acta pharmacologica Sinica 2017 Jan;38(1):69-79
Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.
Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Ma X, Peng J, Liu K
Oncotarget 2017 Jan 31;8(5):8622-8632
Oncotarget 2017 Jan 31;8(5):8622-8632
Formaldehyde alters triglyceride synthesis and very low-density lipoprotein secretion in a time-dependent manner.
Bai J, Wang P, Liu Y, Zhang Y, Li Y, He Z, Hou L, Liang R
Environmental toxicology and pharmacology 2017 Dec;56:15-20
Environmental toxicology and pharmacology 2017 Dec;56:15-20
CDC5L drives FAH expression to promote metabolic reprogramming in melanoma.
Gu Z, Zhang H, Li Y, Shen S, Yin X, Zhang W, Cheng R, Zhang Y, Zhang X, Chen H, Huang B, Cao Y
Oncotarget 2017 Dec 26;8(69):114328-114343
Oncotarget 2017 Dec 26;8(69):114328-114343
Protective effects of glycyrrhizic acid from edible botanical glycyrrhiza glabra against non-alcoholic steatohepatitis in mice.
Wang C, Duan X, Sun X, Liu Z, Sun P, Yang X, Sun H, Liu K, Meng Q
Food & function 2016 Sep 14;7(9):3716-23
Food & function 2016 Sep 14;7(9):3716-23
MicroRNA-24 promotes 3T3-L1 adipocyte differentiation by directly targeting the MAPK7 signaling.
Jin M, Wu Y, Wang J, Chen J, Huang Y, Rao J, Feng C
Biochemical and biophysical research communications 2016 May 20;474(1):76-82
Biochemical and biophysical research communications 2016 May 20;474(1):76-82
Gestational dietary betaine supplementation suppresses hepatic expression of lipogenic genes in neonatal piglets through epigenetic and glucocorticoid receptor-dependent mechanisms.
Cai D, Wang J, Jia Y, Liu H, Yuan M, Dong H, Zhao R
Biochimica et biophysica acta 2016 Jan;1861(1):41-50
Biochimica et biophysica acta 2016 Jan;1861(1):41-50
HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress.
Wang MD, Wu H, Huang S, Zhang HL, Qin CJ, Zhao LH, Fu GB, Zhou X, Wang XM, Tang L, Wen W, Yang W, Tang SH, Cao D, Guo LN, Zeng M, Wu MC, Yan HX, Wang HY
Oncotarget 2016 Feb 9;7(6):6711-26
Oncotarget 2016 Feb 9;7(6):6711-26
Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.
Wang MD, Wu H, Fu GB, Zhang HL, Zhou X, Tang L, Dong LW, Qin CJ, Huang S, Zhao LH, Zeng M, Wu MC, Yan HX, Wang HY
Hepatology (Baltimore, Md.) 2016 Apr;63(4):1272-86
Hepatology (Baltimore, Md.) 2016 Apr;63(4):1272-86
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 21923-1-AP(ACACA antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skeletal muscle using 21923-1-AP(ACACA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACC1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ACC1. This antibody recognizes human,mouse,rat antigen. The ACC1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
