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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- HPA015055 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA015055, RRID:AB_1845435
- Product name
- Anti-BRD4
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human BRD4, Gene description: bromodomain containing 4, Alternative Gene Names: CAP, HUNK1, HUNKI, MCAP, Validated applications: IHC, ICC, Uniprot ID: O60885, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references A gene–environment-induced epigenetic program initiates tumorigenesis
Aggregation and disaggregation features of the human proteome
A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3AR882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and Leukemogenesis
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer
Potent and selective bivalent inhibitors of BET bromodomains
Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expression
Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils
Automated Learning of Subcellular Variation among Punctate Protein Patterns and a Generative Model of Their Relation to Microtubules
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Alonso-Curbelo D, Ho Y, Burdziak C, Maag J, Morris J, Chandwani R, Chen H, Tsanov K, Barriga F, Luan W, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson J, Mazutis L, Leach S, Koche R, Pe’er D, Lowe S
Nature 2021;590(7847):642-648
Nature 2021;590(7847):642-648
Aggregation and disaggregation features of the human proteome
Määttä T, Rettel M, Sridharan S, Helm D, Kurzawa N, Stein F, Savitski M
Molecular Systems Biology 2020;16(10)
Molecular Systems Biology 2020;16(10)
A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3AR882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and Leukemogenesis
Lu R, Wang J, Ren Z, Yin J, Wang Y, Cai L, Wang G
Cancer Research 2019;79(14):3583-3594
Cancer Research 2019;79(14):3583-3594
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer
Shah N, Wang P, Wongvipat J, Karthaus W, Abida W, Armenia J, Rockowitz S, Drier Y, Bernstein B, Long H, Freedman M, Arora V, Zheng D, Sawyers C
eLife 2017;6
eLife 2017;6
Potent and selective bivalent inhibitors of BET bromodomains
Waring M, Chen H, Rabow A, Walker G, Bobby R, Boiko S, Bradbury R, Callis R, Clark E, Dale I, Daniels D, Dulak A, Flavell L, Holdgate G, Jowitt T, Kikhney A, McAlister M, Méndez J, Ogg D, Patel J, Petteruti P, Robb G, Robers M, Saif S, Stratton N, Svergun D, Wang W, Whittaker D, Wilson D, Yao Y
Nature Chemical Biology 2016;12(12):1097-1104
Nature Chemical Biology 2016;12(12):1097-1104
Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expression
Li G, Guo W, Zhang Y, Seng J, Zhang H, Ma X, Zhang G, Li J, Yan B, Tang H, Li S, Wang L, Zhang S
Oncotarget 2015;7(3):2462-2474
Oncotarget 2015;7(3):2462-2474
Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils
Zimmermann M, Aguilera F, Castellucci M, Rossato M, Costa S, Lunardi C, Ostuni R, Girolomoni G, Natoli G, Bazzoni F, Tamassia N, Cassatella M
Nature Communications 2015;6(1)
Nature Communications 2015;6(1)
Automated Learning of Subcellular Variation among Punctate Protein Patterns and a Generative Model of Their Relation to Microtubules
Tresch A, Johnson G, Li J, Shariff A, Rohde G, Murphy R
PLOS Computational Biology 2015;11(12):e1004614
PLOS Computational Biology 2015;11(12):e1004614
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Zuber J, Shi J, Wang E, Rappaport A, Herrmann H, Sison E, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor M, Johns C, Chicas A, Mulloy J, Kogan S, Brown P, Valent P, Bradner J, Lowe S, Vakoc C
Nature 2011;478(7370):524-528
Nature 2011;478(7370):524-528
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
- Sample type
- Human
