10292-1-AP

antibody from Proteintech Group

Targeting: CALR cC1qR, CRT, FLJ26680, RO, SSA

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

10292-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#10292-1-AP, RRID:AB_2069615

Product name

calreticulin antibody

Antibody type

Polyclonal

Description

KD/KO validated calreticulin antibody (Cat. #10292-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

miRNA-mRNA Regulatory Network Reveals miRNAs in HCT116 in Response to Folic Acid Deficiency via Regulating Vital Genes of Endoplasmic Reticulum Stress Pathway.

Lu L, Zhao H, Liu J, Zhang Y, Wang X
BioMed research international 2021;2021:6650181

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Methionine enkephalin (MENK) suppresses lung cancer by regulating the Bcl-2/Bax/caspase-3 signaling pathway and enhancing natural killer cell-driven tumor immunity.

Zhang S, Liu N, Ma M, Huang H, Handley M, Bai X, Shan F
International immunopharmacology 2021 Sep;98:107837

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Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.

Luo L, Qin B, Jiang M, Xie L, Luo Z, Guo X, Zhang J, Li X, Zhu C, Du Y, Peng L, You J
Journal of nanobiotechnology 2021 Sep 30;19(1):297

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Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer.

Jin F, Qi J, Liu D, You Y, Shu G, Du Y, Wang J, Xu X, Ying X, Ji J, Du Y
Journal of controlled release : official journal of the Controlled Release Society 2021 Sep 10;337:90-104

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Calreticulin as a special marker to distinguish dental pulp stem cells from gingival mesenchymal stem cells.

Lei T, Wang J, Liu Y, Chen P, Zhang Z, Zhang X, Wang X, Li Q, Du H
International journal of biological macromolecules 2021 May 1;178:229-239

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The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity.

Nguyen DT, Le TM, Hattori T, Takarada-Iemata M, Ishii H, Roboon J, Tamatani T, Kannon T, Hosomichi K, Tajima A, Taniuchi S, Miyake M, Oyadomari S, Tanaka T, Kato N, Saito S, Mori K, Hori O
Scientific reports 2021 Jun 22;11(1):13086

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Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer.

Ye J, Qi L, Du Z, Yu L, Chen K, Li R, Feng R, Zhai W
Aging 2021 Feb 11;13(4):5607-5620

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Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.

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Nature metabolism 2020 Mar;2(3):256-269

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NIR-Triggered Sequentially Responsive Nanocarriers Amplified Cascade Synergistic Effect of Chemo-Photodynamic Therapy with Inspired Antitumor Immunity.

Jin F, Qi J, Zhu M, Liu D, You Y, Shu G, Du Y, Wang J, Yu H, Sun M, Xu X, Shen Q, Ying X, Ji J, Du Y
ACS applied materials & interfaces 2020 Jul 22;12(29):32372-32387

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Raman spectroscopy as a quick tool to assess purity of extracellular vesicle preparations and predict their functionality.

Gualerzi A, Kooijmans SAA, Niada S, Picciolini S, Brini AT, Camussi G, Bedoni M
Journal of extracellular vesicles 2019;8(1):1568780

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Naphthyl quinoxaline thymidine conjugate is a potent anticancer agent post UVA activation and elicits marked inhibition of tumor growth through vaccination.

Yuan Y, Wang Z, Yang R, Qian T, Zhou Q
European journal of medicinal chemistry 2019 Jun 1;171:255-264

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Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death.

Li W, Yang J, Luo L, Jiang M, Qin B, Yin H, Zhu C, Yuan X, Zhang J, Luo Z, Du Y, Li Q, Lou Y, Qiu Y, You J
Nature communications 2019 Jul 26;10(1):3349

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A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.

Shi J, Hu X, Guo Y, Wang L, Ji J, Li J, Zhang ZR
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096

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Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.

Chen JL, Hung CT, Keller JJ, Lin HC, Wu YJ
BMC ophthalmology 2019 Aug 2;19(1):168

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Identification of PGAM1 as a putative therapeutic target for pancreatic ductal adenocarcinoma metastasis using quantitative proteomics.

Liu X, Weng Y, Liu P, Sui Z, Zhou L, Huang Y, Zhang L, Zhang Y, Tan X
OncoTargets and therapy 2018;11:3345-3357

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Exosomes derived from breast cancer lung metastasis subpopulations promote tumor self-seeding.

Huang H, Zheng X, Cai C, Yao Z, Lu S, Meng X, Miao Y, He Z, Cai C, Zou F
Biochemical and biophysical research communications 2018 Sep 3;503(1):242-248

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Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes.

Lakhter AJ, Pratt RE, Moore RE, Doucette KK, Maier BF, DiMeglio LA, Sims EK
Diabetologia 2018 May;61(5):1124-1134

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The multidisciplinary support in preventing alcohol relapse after liver transplantation: A single-center experience.

Attilia ML, Lattanzi B, Ledda R, Galli AM, Farcomeni A, Rotondo C, Di Gregorio V, Mennini G, Poli E, Attilia F, Ginanni Corradini S, Rossi M, Merli M
Clinical transplantation 2018 May;32(5):e13243

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Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.

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Scientific reports 2018 Jul 2;8(1):9972

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Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, Hu J, Blackstone C, Zhu D, Teng J, Chen J
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Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling.

Wu Y, Xu X, Ma L, Yi Q, Sun W, Tang L
The international journal of biochemistry & cell biology 2017 Sep;90:103-113

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Combination of CALR and PDIA3 is a potential prognostic biomarker for non-small cell lung cancer.

Wang K, Li H, Chen R, Zhang Y, Sun XX, Huang W, Bian H, Chen ZN
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Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.

Lin JJ, Wang RY, Chen JC, Chiu CC, Liao MH, Wu YJ
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FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.

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Yao W, Fan W, Huang C, Zhong H, Chen X, Zhang W
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Proteomic analysis of the differences in orbital protein expression in thyroid orbitopathy.

Cheng KC, Huang HH, Hung CT, Chen CC, Wu WC, Suen JL, Chen KJ, Wu YJ, Chang CH
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A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas.

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The Journal of biological chemistry 2011 Aug 12;286(32):28343-56

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Identification of low-abundance proteins via fractionation of the urine proteome with weak anion exchange chromatography.

Lu CM, Wu YJ, Chen CC, Hsu JL, Chen JC, Chen JY, Huang CH, Ko YC
Proteome science 2011 Apr 8;9:17

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Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.

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Journal of proteome research 2010 Mar 5;9(3):1402-15

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

COLO 320 cells were subjected to SDS PAGE followed by western blot with 10292-1-AP(calreticulin antibody) at dilution of 1:600

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human ovary tumor using 10292-1-AP(calreticulin antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The calreticulin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human calreticulin. This antibody recognizes human,mouse,rat antigen. The calreticulin antibody has been validated for the following applications: ELISA, WB, IHC analysis.

Appendix

10292-1-AP.pdf

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