MRPS30

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52. Transcript variants using alternative promoters or polyA sites have been mentioned in the literature but the complete description of these sequences is not available. [provided by RefSeq, Jul 2008]

Description

mitochondrial ribosomal protein S30

Protein family

Mapped to UniProt SWISS-PROT, Ribosomal proteins

Chromosome

5:p12 (44809027 - 44820530)

Ensembl ID

ENSG00000112996  (ver. 74.37)

Orthologs

-

UniProt

Q9NP92

neXtProt

NX_Q9NP92

Human splice variants