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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [20]
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- Product number
- D044-3 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-18/IL-1F4 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. This antibody reacts with human IL-18 on Immunoprecipitation.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 125-2H
- Vial size
- 100 ug
- Storage
- This antibody solution is stable for one year from the date of purchase when stored at -20°C.
Submitted references Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j.
Production and regulation of interleukin-1 family cytokines at the materno-fetal interface.
IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD.
Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling.
Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection.
Bacillus Calmette-Guérin (BCG) Revaccination of Adults with Latent Mycobacterium tuberculosis Infection Induces Long-Lived BCG-Reactive NK Cell Responses.
Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors.
Type I IFNs and IL-18 regulate the antiviral response of primary human γδ T cells against dendritic cells infected with Dengue virus.
The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways.
Leptin enhances the secretion of interleukin (IL)-18, but not IL-1β, from human monocytes via activation of caspase-1.
Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.
Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration.
Development and validation of sandwich ELISA microarrays with minimal assay interference.
Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays.
Statin-induced proinflammatory response in mitogen-activated peripheral blood mononuclear cells through the activation of caspase-1 and IL-18 secretion in monocytes.
Statin-induced proinflammatory response in mitogen-activated peripheral blood mononuclear cells through the activation of caspase-1 and IL-18 secretion in monocytes.
Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis.
The proatherogenic cytokine interleukin-18 is secreted by human adipocytes.
IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction.
IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction.
Nuñez SY, Ziblat A, Secchiari F, Torres NI, Sierra JM, Raffo Iraolagoitia XL, Araya RE, Domaica CI, Fuertes MB, Zwirner NW
Journal of immunology (Baltimore, Md. : 1950) 2018 Feb 1;200(3):1008-1015
Journal of immunology (Baltimore, Md. : 1950) 2018 Feb 1;200(3):1008-1015
Production and regulation of interleukin-1 family cytokines at the materno-fetal interface.
Scott LM, Bryant AH, Rees A, Down B, Jones RH, Thornton CA
Cytokine 2017 Nov;99:194-202
Cytokine 2017 Nov;99:194-202
IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD.
Briend E, Ferguson GJ, Mori M, Damera G, Stephenson K, Karp NA, Sethi S, Ward CK, Sleeman MA, Erjefält JS, Finch DK
Respiratory research 2017 Aug 22;18(1):159
Respiratory research 2017 Aug 22;18(1):159
Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling.
Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X
Scientific reports 2016 Sep 2;6:32320
Scientific reports 2016 Sep 2;6:32320
Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection.
Goodier MR, Rodriguez-Galan A, Lusa C, Nielsen CM, Darboe A, Moldoveanu AL, White MJ, Behrens R, Riley EM
Journal of immunology (Baltimore, Md. : 1950) 2016 Jul 1;197(1):313-25
Journal of immunology (Baltimore, Md. : 1950) 2016 Jul 1;197(1):313-25
Bacillus Calmette-Guérin (BCG) Revaccination of Adults with Latent Mycobacterium tuberculosis Infection Induces Long-Lived BCG-Reactive NK Cell Responses.
Suliman S, Geldenhuys H, Johnson JL, Hughes JE, Smit E, Murphy M, Toefy A, Lerumo L, Hopley C, Pienaar B, Chheng P, Nemes E, Hoft DF, Hanekom WA, Boom WH, Hatherill M, Scriba TJ
Journal of immunology (Baltimore, Md. : 1950) 2016 Aug 15;197(4):1100-1110
Journal of immunology (Baltimore, Md. : 1950) 2016 Aug 15;197(4):1100-1110
Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors.
Spallanzani RG, Torres NI, Avila DE, Ziblat A, Iraolagoitia XL, Rossi LE, Domaica CI, Fuertes MB, Rabinovich GA, Zwirner NW
Journal of immunology (Baltimore, Md. : 1950) 2015 Sep 1;195(5):2141-8
Journal of immunology (Baltimore, Md. : 1950) 2015 Sep 1;195(5):2141-8
Type I IFNs and IL-18 regulate the antiviral response of primary human γδ T cells against dendritic cells infected with Dengue virus.
Tsai CY, Liong KH, Gunalan MG, Li N, Lim DS, Fisher DA, MacAry PA, Leo YS, Wong SC, Puan KJ, Wong SB
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3890-900
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3890-900
The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways.
Hedl M, Zheng S, Abraham C
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5924-32
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5924-32
Leptin enhances the secretion of interleukin (IL)-18, but not IL-1β, from human monocytes via activation of caspase-1.
Jitprasertwong P, Jaedicke KM, Nile CJ, Preshaw PM, Taylor JJ
Cytokine 2014 Feb;65(2):222-30
Cytokine 2014 Feb;65(2):222-30
Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.
Hu H, Kwun J, Aizenstein BD, Knechtle SJ
Transplantation 2009 Jun 27;87(12):1814-20
Transplantation 2009 Jun 27;87(12):1814-20
Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration.
Venkatesan B, Valente AJ, Reddy VS, Siwik DA, Chandrasekar B
American journal of physiology. Heart and circulatory physiology 2009 Aug;297(2):H874-86
American journal of physiology. Heart and circulatory physiology 2009 Aug;297(2):H874-86
Development and validation of sandwich ELISA microarrays with minimal assay interference.
Gonzalez RM, Seurynck-Servoss SL, Crowley SA, Brown M, Omenn GS, Hayes DF, Zangar RC
Journal of proteome research 2008 Jun;7(6):2406-14
Journal of proteome research 2008 Jun;7(6):2406-14
Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays.
Pfleger C, Schloot N, ter Veld F
Journal of immunological methods 2008 Jan 1;329(1-2):214-8
Journal of immunological methods 2008 Jan 1;329(1-2):214-8
Statin-induced proinflammatory response in mitogen-activated peripheral blood mononuclear cells through the activation of caspase-1 and IL-18 secretion in monocytes.
Coward WR, Marei A, Yang A, Vasa-Nicotera MM, Chow SC
Journal of immunology (Baltimore, Md. : 1950) 2006 May 1;176(9):5284-92
Journal of immunology (Baltimore, Md. : 1950) 2006 May 1;176(9):5284-92
Statin-induced proinflammatory response in mitogen-activated peripheral blood mononuclear cells through the activation of caspase-1 and IL-18 secretion in monocytes.
Coward WR, Marei A, Yang A, Vasa-Nicotera MM, Chow SC
Journal of immunology (Baltimore, Md. : 1950) 2006 May 1;176(9):5284-92
Journal of immunology (Baltimore, Md. : 1950) 2006 May 1;176(9):5284-92
Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis.
Haas CS, Amin MA, Allen BB, Ruth JH, Haines GK 3rd, Woods JM, Koch AE
Arthritis and rheumatism 2006 Aug;54(8):2402-14
Arthritis and rheumatism 2006 Aug;54(8):2402-14
The proatherogenic cytokine interleukin-18 is secreted by human adipocytes.
Skurk T, Kolb H, Müller-Scholze S, Röhrig K, Hauner H, Herder C
European journal of endocrinology 2005 Jun;152(6):863-8
European journal of endocrinology 2005 Jun;152(6):863-8
IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction.
Wu C, Sakorafas P, Miller R, McCarthy D, Scesney S, Dixon R, Ghayur T
Journal of immunology (Baltimore, Md. : 1950) 2003 Jun 1;170(11):5571-7
Journal of immunology (Baltimore, Md. : 1950) 2003 Jun 1;170(11):5571-7
IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction.
Wu C, Sakorafas P, Miller R, McCarthy D, Scesney S, Dixon R, Ghayur T
Journal of immunology (Baltimore, Md. : 1950) 2003 Jun 1;170(11):5571-7
Journal of immunology (Baltimore, Md. : 1950) 2003 Jun 1;170(11):5571-7
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