orb27609
antibody from Biorbyt
Targeting: CYP2D6
CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- orb27609 - Provider product page
- Provider
- Biorbyt
- Proper citation
- Biorbyt Cat#orb27609, RRID:AB_10998281
- Product name
- CYP2D6 antibody
- Antibody type
- Polyclonal
- Description
- Rabbit Polyclonal to CYP2D6. Cytochrome P450 2D6 (CYP2D6) is one of the most important enzymes involved in the metabolism of xenobiotics in the body. It is a member of Cytochrome P450, family 2, subfamily D, polypeptide 6. Its gene is mapped to chromosome 22q13.1. It has got 497 amino acid proteins which shares 73% sequence identity with the rat protein. CYP2D6 is highly expressed in human liver. CYP2D6 is the major isozyme involved in the formation of N-hydroxyprocainamide, a metabolite potentially involved in the drug-induced lupus syndrome observed with procainamide
- Reactivity
- Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 100 μg
- Concentration
- 500μg/ml.
- Storage
- Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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Supportive validation
- Submitted by
- Biorbyt (provider)
- Main image
- Experimental details
- Western blot analysis of Lane 1: Rat Liver Tissue Lysate, Lane 2: Rat Kidney Tissue Lysate, Lane 3: Rat Brain Tissue Lysate using CYP2D6 antibody.