orb137674

antibody from Biorbyt

Targeting: KIT C-Kit, CD117, PBT, SCFR

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

orb137674

Provider

Biorbyt

Product name

Anti-Desmin antibody

Antibody type

Monoclonal

Description

Mouse monoclonal to Desmin. Desmin is a 53 kDa intermediate filament protein that exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.

Reactivity

Human, Rat, Chicken/Avian, Hamster

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

D33

Vial size

1 ml

Storage

Store at 4°C, or in small aliquots at-20°C.