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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN362293 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pTyr721 (N-E-Y (p) -M-D) derived from Human c-Kit. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pTyr721
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references MicroRNA-193b regulates c-Kit proto-oncogene and represses cell proliferation in acute myeloid leukemia.
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility.
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.
Colipase stabilizes the lid domain of pancreatic triglyceride lipase.
Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL).
Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.
Gao XN, Lin J, Gao L, Li YH, Wang LL, Yu L
Leukemia research 2011 Sep;35(9):1226-32
Leukemia research 2011 Sep;35(9):1226-32
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility.
Blume-Jensen P, Jiang G, Hyman R, Lee KF, O'Gorman S, Hunter T
Nature genetics 2000 Feb;24(2):157-62
Nature genetics 2000 Feb;24(2):157-62
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.
Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishiguro S, Kawano K, Hanada M, Kurata A, Takeda M, Muhammad Tunio G, Matsuzawa Y, Kanakura Y, Shinomura Y, Kitamura Y
Science (New York, N.Y.) 1998 Jan 23;279(5350):577-80
Science (New York, N.Y.) 1998 Jan 23;279(5350):577-80
Colipase stabilizes the lid domain of pancreatic triglyceride lipase.
Lowe ME
The Journal of biological chemistry 1997 Jan 3;272(1):9-12
The Journal of biological chemistry 1997 Jan 3;272(1):9-12
Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL).
Sattler M, Salgia R, Shrikhande G, Verma S, Pisick E, Prasad KV, Griffin JD
The Journal of biological chemistry 1997 Apr 11;272(15):10248-53
The Journal of biological chemistry 1997 Apr 11;272(15):10248-53
Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.
Nocka K, Tan JC, Chiu E, Chu TY, Ray P, Traktman P, Besmer P
The EMBO journal 1990 Jun;9(6):1805-13
The EMBO journal 1990 Jun;9(6):1805-13
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