323408

antibody from BioLegend
Targeting: KIT C-Kit, CD117, PBT, SCFR
Provider product page for 323408

Antibody data

Product number
323408 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#323408, RRID:AB_755978
Product name
PE anti-human CD117 (c-kit)
Antibody type
Monoclonal
Antigen
MOLM-1 megakaryocitic cell line
Description
CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemic cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117, and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells. The A3C6E2 antibody potently blocks the binding of SCF.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
KIT protein structure - 323408 shown in red.