Explore
Validate
Learn
Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [3]
Submit
Validation data
Reference
Comment
Report error
- Product number
- GTX70207 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX70207, RRID:AB_371982
- Product name
- Jab1 antibody [8H8.5]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse, Drosophila
- Host
- Mouse
Submitted references CSN6 drives carcinogenesis by positively regulating Myc stability.
Can hyperthermic intraperitoneal chemotherapy efficiency be improved by blocking the DNA repair factor COP9 signalosome?
In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1.
The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis.
Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif.
The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.
Chen J, Shin JH, Zhao R, Phan L, Wang H, Xue Y, Post SM, Ho Choi H, Chen JS, Wang E, Zhou Z, Tseng C, Gully C, Velazquez-Torres G, Fuentes-Mattei E, Yeung G, Qiao Y, Chou PC, Su CH, Hsieh YC, Hsu SL, Ohshiro K, Shaikenov T, Wang H, Yeung SC, Lee MH
Nature communications 2014 Nov 14;5:5384
Nature communications 2014 Nov 14;5:5384
Can hyperthermic intraperitoneal chemotherapy efficiency be improved by blocking the DNA repair factor COP9 signalosome?
Feist M, Huang X, Müller JM, Rau B, Dubiel W
International journal of colorectal disease 2014 Jun;29(6):673-80
International journal of colorectal disease 2014 Jun;29(6):673-80
In utero exposure to dioxin causes neocortical dysgenesis through the actions of p27Kip1.
Mitsuhashi T, Yonemoto J, Sone H, Kosuge Y, Kosaki K, Takahashi T
Proceedings of the National Academy of Sciences of the United States of America 2010 Sep 14;107(37):16331-5
Proceedings of the National Academy of Sciences of the United States of America 2010 Sep 14;107(37):16331-5
The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis.
da Silva Correia J, Miranda Y, Leonard N, Ulevitch RJ
The Journal of biological chemistry 2007 Apr 27;282(17):12557-65
The Journal of biological chemistry 2007 Apr 27;282(17):12557-65
Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif.
Burger-Kentischer A, Finkelmeier D, Thiele M, Schmucker J, Geiger G, Tovar GE, Bernhagen J
FEBS letters 2005 Mar 14;579(7):1693-701
FEBS letters 2005 Mar 14;579(7):1693-701
The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.
Doronkin S, Djagaeva I, Beckendorf SK
Developmental cell 2003 May;4(5):699-710
Developmental cell 2003 May;4(5):699-710
No comments: Submit comment
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Customer Review using GTX70207 - D10 T cells were lysed in IP buffer (20mM Tris-HCl, pH 7.5, 50mM NaCl, 50mM NaF, 10mM -glycerophosphate, 1% Triton X-100, 1mM PMSF).
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Part of a customer review using GTX70207
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Detection of human Jab1 protein in HeLa whole cell lysate using GeneTex monoclonal antibody GTX70207
