Antibody data
- Antibody Data
- Antigen structure
- References [33]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 22665-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22665-1-AP, RRID:AB_2631204
- Product name
- FSHR antibody
- Antibody type
- Polyclonal
- Description
- FSHR antibody (Cat. #22665-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FSH modulated cartilage ECM metabolism by targeting the PKA/CREB/SOX9 pathway.
TRIB3 regulates FSHR expression in human granulosa cells under high levels of free fatty acids.
Orcinol glucoside improves the depressive-like behaviors of perimenopausal depression mice through modulating activity of hypothalamic-pituitary-adrenal/ovary axis and activating BDNF- TrkB-CREB signaling pathway.
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
The function of BAP18 on modulation of androgen receptor action in luteinized granulosa cells from normal weight women with and without PCOS.
Human amnion-derived mesenchymal stem cells improved the reproductive function of age-related diminished ovarian reserve in mice through Ampk/FoxO3a signaling pathway.
CXCL12 and its receptors regulate granulosa cell apoptosis in PCOS rats and human KGN tumor cells.
Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway.
MiR-34c-5p promotes granulosa cells apoptosis by targeting Bcl2 in broody goose (Anser cygnoides).
After cyclophosphamide exposure, granulosa cells recover their anti-müllerian hormone-producing ability but not their numbers.
Role of FSH and FSH receptor on HUVECs migration.
Synergistic effect of Huyang Yangkun Formula and embryonic stem cells on 4-vinylcyclohexene diepoxide induced premature ovarian insufficiency in mice.
Novel ovarian endometriosis model causes infertility via iron-mediated oxidative stress in mice.
Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells.
Chlorogenic acid rescues zearalenone induced injury to mouse ovarian granulosa cells.
Small extracellular vesicles derived from embryonic stem cells restore ovarian function of premature ovarian failure through PI3K/AKT signaling pathway.
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8+CD28- T cells.
Cell-free mitochondrial DNA increases granulosa cell apoptosis and reduces aged oocyte blastocyst development in the mouse.
Melatonin alleviates β-zearalenol and HT-2 toxin-induced apoptosis and oxidative stress in bovine ovarian granulosa cells.
Molecular mechanism of FSHR expression induced by BMP15 in human granulosa cells.
Novel FSHR mutations in Han Chinese women with sporadic premature ovarian insufficiency.
Follicular fluid humanin concentration is related to ovarian reserve markers and clinical pregnancy after IVF-ICSI: a pilot study.
miR-323-3p regulates the steroidogenesis and cell apoptosis in polycystic ovary syndrome (PCOS) by targeting IGF-1.
Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol.
Silencing of LncRNA steroid receptor RNA activator attenuates polycystic ovary syndrome in mice.
HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress.
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.
Role of RAB5A in FSHR-mediated signal transduction in human granulosa cells.
Up-Regulation of Long Noncoding RNA SRA Promotes Cell Growth, Inhibits Cell Apoptosis, and Induces Secretion of Estradiol and Progesterone in Ovarian Granular Cells of Mice.
Vitamin D receptor expression and potential role of vitamin D on cell proliferation and steroidogenesis in goat ovarian granulosa cells.
A novel homozygous mutation in the FSHR gene is causative for primary ovarian insufficiency.
Novel WT1 Missense Mutations in Han Chinese Women with Premature Ovarian Failure.
Zhang M, Wang Y, Huan Z, Liu Y, Zhang W, Kong D, Kong L, Xu J
Journal of bone and mineral metabolism 2021 Sep;39(5):769-779
Journal of bone and mineral metabolism 2021 Sep;39(5):769-779
TRIB3 regulates FSHR expression in human granulosa cells under high levels of free fatty acids.
Wang N, Si C, Xia L, Wu X, Zhao S, Xu H, Ding Z, Niu Z
Reproductive biology and endocrinology : RB&E 2021 Sep 9;19(1):139
Reproductive biology and endocrinology : RB&E 2021 Sep 9;19(1):139
Orcinol glucoside improves the depressive-like behaviors of perimenopausal depression mice through modulating activity of hypothalamic-pituitary-adrenal/ovary axis and activating BDNF- TrkB-CREB signaling pathway.
Li J, He P, Zhang J, Li N
Phytotherapy research : PTR 2021 Oct;35(10):5795-5807
Phytotherapy research : PTR 2021 Oct;35(10):5795-5807
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
Xi H, Ren F, Li Y, Du Y, Wang L, Hu J
Biology of reproduction 2021 Nov 15;105(5):1344-1354
Biology of reproduction 2021 Nov 15;105(5):1344-1354
LncRNA ZNF674-AS1 regulates granulosa cell glycolysis and proliferation by interacting with ALDOA.
Li D, Wang X, Li G, Dang Y, Zhao S, Qin Y
Cell death discovery 2021 May 16;7(1):107
Cell death discovery 2021 May 16;7(1):107
The function of BAP18 on modulation of androgen receptor action in luteinized granulosa cells from normal weight women with and without PCOS.
Tang T, Jiao J, Li D, Sun G, Lin L, Wang C, Wang S, Zou R, Liu W, Zhao Y, Wang X
Molecular and cellular endocrinology 2021 May 1;527:111228
Molecular and cellular endocrinology 2021 May 1;527:111228
Human amnion-derived mesenchymal stem cells improved the reproductive function of age-related diminished ovarian reserve in mice through Ampk/FoxO3a signaling pathway.
Liu H, Jiang C, La B, Cao M, Ning S, Zhou J, Yan Z, Li C, Cui Y, Ma X, Wang M, Chen L, Yu Y, Chen F, Zhang Y, Wu H, Liu J, Qin L
Stem cell research & therapy 2021 Jun 2;12(1):317
Stem cell research & therapy 2021 Jun 2;12(1):317
CXCL12 and its receptors regulate granulosa cell apoptosis in PCOS rats and human KGN tumor cells.
Jin L, Ren L, Lu J, Wen X, Zhuang S, Geng T, Zhang Y
Reproduction (Cambridge, England) 2021 Feb;161(2):145-157
Reproduction (Cambridge, England) 2021 Feb;161(2):145-157
Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway.
Wang Y, Li N, Zeng Z, Tang L, Zhao S, Zhou F, Zhou L, Xia W, Zhu C, Rao M
Molecular human reproduction 2021 Feb 5;27(2)
Molecular human reproduction 2021 Feb 5;27(2)
MiR-34c-5p promotes granulosa cells apoptosis by targeting Bcl2 in broody goose (Anser cygnoides).
Hou L, Ji W, Gu T, Weng K, Liu D, Zhang Y, Zhang Y, Xu Q, Chen G
Animal biotechnology 2021 Feb 25;:1-9
Animal biotechnology 2021 Feb 25;:1-9
After cyclophosphamide exposure, granulosa cells recover their anti-müllerian hormone-producing ability but not their numbers.
Kim J, You S
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2021 Aug;99(8):807-813
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2021 Aug;99(8):807-813
Role of FSH and FSH receptor on HUVECs migration.
Tan D, Zhao Y, Ma D, Tong F
Gene therapy 2021 Apr;28(3-4):155-161
Gene therapy 2021 Apr;28(3-4):155-161
Synergistic effect of Huyang Yangkun Formula and embryonic stem cells on 4-vinylcyclohexene diepoxide induced premature ovarian insufficiency in mice.
Li M, Xie L, Li Y, Liu J, Nie G, Yang H
Chinese medicine 2020;15:83
Chinese medicine 2020;15:83
Novel ovarian endometriosis model causes infertility via iron-mediated oxidative stress in mice.
Hayashi S, Nakamura T, Motooka Y, Ito F, Jiang L, Akatsuka S, Iwase A, Kajiyama H, Kikkawa F, Toyokuni S
Redox biology 2020 Oct;37:101726
Redox biology 2020 Oct;37:101726
Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells.
Sun N, Zhang Y, Hou Y, Yi Y, Guo J, Zheng X, Sun P, Sun Y, Khan A, Li H
Animals : an open access journal from MDPI 2020 Nov 4;10(11)
Animals : an open access journal from MDPI 2020 Nov 4;10(11)
Chlorogenic acid rescues zearalenone induced injury to mouse ovarian granulosa cells.
Yi Y, Wan S, Hou Y, Cheng J, Guo J, Wang S, Khan A, Sun N, Li H
Ecotoxicology and environmental safety 2020 May;194:110401
Ecotoxicology and environmental safety 2020 May;194:110401
Small extracellular vesicles derived from embryonic stem cells restore ovarian function of premature ovarian failure through PI3K/AKT signaling pathway.
Liu M, Qiu Y, Xue Z, Wu R, Li J, Niu X, Yuan J, Wang Y, Wu Q
Stem cell research & therapy 2020 Jan 3;11(1):3
Stem cell research & therapy 2020 Jan 3;11(1):3
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8+CD28- T cells.
Yin N, Wu C, Qiu J, Zhang Y, Bo L, Xu Y, Shi M, Zhu S, Yang G, Mao C
Stem cell research & therapy 2020 Feb 4;11(1):49
Stem cell research & therapy 2020 Feb 4;11(1):49
Cell-free mitochondrial DNA increases granulosa cell apoptosis and reduces aged oocyte blastocyst development in the mouse.
Liu Y, Shen Q, Li H, Xiang W, Zhang L
Reproductive toxicology (Elmsford, N.Y.) 2020 Dec;98:278-285
Reproductive toxicology (Elmsford, N.Y.) 2020 Dec;98:278-285
Melatonin alleviates β-zearalenol and HT-2 toxin-induced apoptosis and oxidative stress in bovine ovarian granulosa cells.
Yang F, Li L, Chen K, Li C, Wang Y, Wang G
Environmental toxicology and pharmacology 2019 May;68:52-60
Environmental toxicology and pharmacology 2019 May;68:52-60
Molecular mechanism of FSHR expression induced by BMP15 in human granulosa cells.
Shimizu K, Nakamura T, Bayasula, Nakanishi N, Kasahara Y, Nagai T, Murase T, Osuka S, Goto M, Iwase A, Kikkawa F
Journal of assisted reproduction and genetics 2019 Jun;36(6):1185-1194
Journal of assisted reproduction and genetics 2019 Jun;36(6):1185-1194
Novel FSHR mutations in Han Chinese women with sporadic premature ovarian insufficiency.
Liu H, Guo T, Gong Z, Yu Y, Zhang Y, Zhao S, Qin Y
Molecular and cellular endocrinology 2019 Jul 15;492:110446
Molecular and cellular endocrinology 2019 Jul 15;492:110446
Follicular fluid humanin concentration is related to ovarian reserve markers and clinical pregnancy after IVF-ICSI: a pilot study.
Rao M, Zhou F, Tang L, Zeng Z, Hu S, Wang Y, Ke D, Cheng G, Xia W, Zhang L, Zhu C
Reproductive biomedicine online 2019 Jan;38(1):108-117
Reproductive biomedicine online 2019 Jan;38(1):108-117
miR-323-3p regulates the steroidogenesis and cell apoptosis in polycystic ovary syndrome (PCOS) by targeting IGF-1.
Wang T, Liu Y, Lv M, Xing Q, Zhang Z, He X, Xu Y, Wei Z, Cao Y
Gene 2019 Jan 30;683:87-100
Gene 2019 Jan 30;683:87-100
Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol.
Guo Y, Zhao M, Bo T, Ma S, Yuan Z, Chen W, He Z, Hou X, Liu J, Zhang Z, Zhu Q, Wang Q, Lin X, Yang Z, Cui M, Liu L, Li Y, Yu C, Qi X, Wang Q, Zhang H, Guan Q, Zhao L, Xuan S, Yan H, Lin Y, Wang L, Li Q, Song Y, Gao L, Zhao J
Cell research 2019 Feb;29(2):151-166
Cell research 2019 Feb;29(2):151-166
Silencing of LncRNA steroid receptor RNA activator attenuates polycystic ovary syndrome in mice.
Li Y, Zhao W, Wang H, Chen C, Zhou D, Li S, Zhang X, Zhao H, Zhou D, Chen B
Biochimie 2019 Feb;157:48-56
Biochimie 2019 Feb;157:48-56
HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress.
Wang Y, Yang C, Elsheikh NAH, Li C, Yang F, Wang G, Li L
Aging 2019 Aug 12;11(15):5535-5547
Aging 2019 Aug 12;11(15):5535-5547
Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.
Gou Y, Li X, Li P, Zhang H, Xu T, Wang H, Wang B, Ma X, Jiang X, Zhang Z
Human reproduction (Oxford, England) 2019 Apr 1;34(4):646-658
Human reproduction (Oxford, England) 2019 Apr 1;34(4):646-658
Role of RAB5A in FSHR-mediated signal transduction in human granulosa cells.
Zhu K, Li S, Liu J, Hong Y, Chen ZJ, Du Y
Reproduction (Cambridge, England) 2018 Jun;155(6):505-514
Reproduction (Cambridge, England) 2018 Jun;155(6):505-514
Up-Regulation of Long Noncoding RNA SRA Promotes Cell Growth, Inhibits Cell Apoptosis, and Induces Secretion of Estradiol and Progesterone in Ovarian Granular Cells of Mice.
Li Y, Wang H, Zhou D, Shuang T, Zhao H, Chen B
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 20;24:2384-2390
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 20;24:2384-2390
Vitamin D receptor expression and potential role of vitamin D on cell proliferation and steroidogenesis in goat ovarian granulosa cells.
Yao X, Zhang G, Guo Y, Ei-Samahy M, Wang S, Wan Y, Han L, Liu Z, Wang F, Zhang Y
Theriogenology 2017 Oct 15;102:162-173
Theriogenology 2017 Oct 15;102:162-173
A novel homozygous mutation in the FSHR gene is causative for primary ovarian insufficiency.
Liu H, Xu X, Han T, Yan L, Cheng L, Qin Y, Liu W, Zhao S, Chen ZJ
Fertility and sterility 2017 Dec;108(6):1050-1055.e2
Fertility and sterility 2017 Dec;108(6):1050-1055.e2
Novel WT1 Missense Mutations in Han Chinese Women with Premature Ovarian Failure.
Wang H, Li G, Zhang J, Gao F, Li W, Qin Y, Chen ZJ
Scientific reports 2015 Sep 11;5:13983
Scientific reports 2015 Sep 11;5:13983
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FSHR antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human FSHR. This antibody recognizes human, mouse antigen. The FSHR antibody has been validated for the following applications: ELISA, WB analysis.