316002

antibody from BioLegend

Targeting: CD52 CDW52, EDDM5, HE5

Immunohistochemistry (Recommended by provider)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

316002

Provider

BioLegend

Proper citation

BioLegend Cat#316002, RRID:AB_389275

Product name

Purified anti-human CD52

Antibody type

Monoclonal

Antigen

Human tonsil

Description

CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression. The HI186 antibody is useful for flow cytometry and immunohistochemistry.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C.