PANK4

This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. [provided by RefSeq, Jul 2008]

Description

Pantothenate kinase 4 (inactive)

Tissue specificity

Low tissue specificity

Subcell location

Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

1 (2508537 - 2526597)

Ensembl ID

ENSG00000157881  (ver. 103.38)

Orthologs

Mouse Pank4: ENSMUSG00000029056

UniProt

Q9NVE7

neXtProt

NX_Q9NVE7

Human splice variants
Mouse splice variants

Protein structure