Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN650702 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (N-Term), (AA 106-138) antibody
- Antibody type
- Polyclonal
- Antigen
- This HRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-138 AA from the N-terminal region of human HRD1.
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term,AA 106-138
- Antibody clone number
- RB15288
- Vial size
- 400 μL
- Concentration
- 2 mg/mL
Submitted references TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.
Enhanced endoplasmic reticulum entry of tumor antigen is crucial for cross-presentation induced by dendritic cell-targeted vaccination.
MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation.
van den Boomen DJ, Timms RT, Grice GL, Stagg HR, Skødt K, Dougan G, Nathan JA, Lehner PJ
Proceedings of the National Academy of Sciences of the United States of America 2014 Aug 5;111(31):11425-30
Proceedings of the National Academy of Sciences of the United States of America 2014 Aug 5;111(31):11425-30
Enhanced endoplasmic reticulum entry of tumor antigen is crucial for cross-presentation induced by dendritic cell-targeted vaccination.
Wang H, Yu X, Guo C, Zuo D, Fisher PB, Subjeck JR, Wang XY
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 15;191(12):6010-21
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 15;191(12):6010-21
MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation.
Burr ML, van den Boomen DJ, Bye H, Antrobus R, Wiertz EJ, Lehner PJ
Proceedings of the National Academy of Sciences of the United States of America 2013 Aug 27;110(35):14290-5
Proceedings of the National Academy of Sciences of the United States of America 2013 Aug 27;110(35):14290-5
No comments: Submit comment
No validations: Submit validation data