ZKSCAN1

This gene encodes a member of the Kruppel C2H2-type zinc-finger family of proteins. This encoded protein may function as a transcription factor that regulates the expression of GABA type-A receptors in the brain. Transcripts from this gene have been shown to form stable and abundant circular RNAs. Elevated expression of this gene has been observed in gastric cancer and the encoded protein may stimulate migration and invasion of human gastric cancer cells. [provided by RefSeq, Oct 2016]

Description

Zinc finger with KRAB and SCAN domains 1

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nuclear bodies, Mitochondria

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

7 (100015572 - 100041689)

Ensembl ID

ENSG00000106261  (ver. 103.38)

Orthologs

Mouse Zkscan1: ENSMUSG00000029729

UniProt

P17029

neXtProt

NX_P17029

Human splice variants
Mouse splice variants

Protein structure