Antibody data
- Antibody Data
- Antigen structure
- References [90]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10371-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10371-2-AP, RRID:AB_2297741
- Product name
- MMP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MMP1 antibody (Cat. #10371-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways.
RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7.
Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF-κB and PI3K/AKT Pathways.
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation.
Chondroprotective and antiarthritic effects of galangin in osteoarthritis: An in vitro and in vivo study.
Pterostilbene Attenuates Particulate Matter-Induced Oxidative Stress, Inflammation and Aging in Keratinocytes.
Oleanolic Acid Nanofibers Attenuated Particulate Matter-Induced Oxidative Stress in Keratinocytes.
Human Exosomes Accelerate Cutaneous Wound Healing by Promoting Collagen Synthesis in a Diabetic Mouse Model.
Curcumol inhibits EBV-positive Nasopharyngeal carcinoma migration and invasion by targeting nucleolin.
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro.
Cold exposure and capsaicin promote 1,2-dimethylhyrazine-induced colon carcinogenesis in rats correlates with extracellular matrix remodeling.
High fibular osteotomy ameliorates medial compartment knee osteoarthritis in a rabbit model.
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Magnolin exhibits anti-inflammatory effects on chondrocytes via the NF-κB pathway for attenuating anterior cruciate ligament transection-induced osteoarthritis.
MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.
METTL3 involves the progression of osteoarthritis probably by affecting ECM degradation and regulating the inflammatory response.
Novel histopathological classification of meningiomas based on dural invasion.
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
UVA influenced the SIRT1-miR-27a-5p-SMAD2-MMP1/COL1/BCL2 axis in human skin primary fibroblasts.
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
ETV4 overexpression promotes progression of non-small cell lung cancer by upregulating PXN and MMP1 transcriptionally.
4-Hydroxy-7-oxo-5-heptenoic acid lactone is a potent inducer of brain cancer cell invasiveness that may contribute to the failure of anti-angiogenic therapies.
Intra-articular collagenase in the spinal facet joint induces pain, DRG neuron dysregulation and increased MMP-1 absent evidence of joint destruction.
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo.
Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway.
p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes.
Protective effects of Erdosteine on interleukin-1β-stimulated inflammation via inhibiting the activation of MAPK, NF-κB, and Wnt/β-catenin signaling pathways in rat osteoarthritis.
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis.
Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1/Smad Pathway.
Tricetin Protects Rat Chondrocytes against IL-1β-Induced Inflammation and Apoptosis.
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes.
Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43.
Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes.
Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways.
Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells.
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
NOV/CCN3 induces cartilage protection by inhibiting PI3K/AKT/mTOR pathway.
Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats.
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway.
MiR-202-3p regulates interleukin-1β-induced expression of matrix metalloproteinase 1 in human nucleus pulposus.
Liraglutide alleviates cardiac fibrosis through inhibiting P4hα-1 expression in STZ-induced diabetic cardiomyopathy.
Concentration dependent effects of fibroblast-like synoviocytes on collagen gel multiscale biomechanics & neuronal signaling: Implications for modeling human ligamentous tissues.
Overexpressed vascular endothelial growth factor in adipose derived stem cells attenuates fibroblasts and skin injuries by ultraviolet radiation.
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma.
Isorhapontigenin Suppresses Interleukin-1β-Induced Inflammation and Cartilage Matrix Damage in Rat Chondrocytes.
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Effects of growth hormone and functional appliance on mandibular growth in an adolescent rat model.
Kaempferol inhibits interleukin‑1β stimulated matrix metalloproteinases by suppressing the MAPK‑associated ERK and P38 signaling pathways.
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes.
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Investigation of the expressions of MMPs and TIMPs between isogeneic and allogeneic rat aortic transplantation.
Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis.
Sinapic Acid Inhibits the IL-1β-Induced Inflammation via MAPK Downregulation in Rat Chondrocytes.
Protective effects of psoralidin on IL‑1β‑induced chondrocyte apoptosis.
Cellular communication promotes mammosphere growth and collective invasion through microtubule‑like structures and angiogenesis.
Overexpression of matrix metalloproteinase-9 in adolescents with primary spontaneous pneumothorax for surgical intervention.
Tumor cell density regulates matrix metalloproteinases for enhanced migration.
Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Collagen I promotes hepatocellular carcinoma cell proliferation by regulating integrin β1/FAK signaling pathway in nonalcoholic fatty liver.
Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation.
Pigment Epithelium-Derived Factor (PEDF) mediates cartilage matrix loss in an age-dependent manner under inflammatory conditions.
MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN.
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma.
CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis.
Conditional knockout of tissue factor pathway inhibitor 2 in vascular endothelial cells accelerates atherosclerotic plaque development in mice.
Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration.
The trophoblast plug during early pregnancy: a deeper insight.
Metallothionein-3 Increases Triple-Negative Breast Cancer Cell Invasiveness via Induction of Metalloproteinase Expression.
Effects of small interfering RNA-mediated downregulation of the Krüppel-like factor 4 gene on collagen metabolism in human hepatic stellate cells.
Potent effects of dioscin against liver fibrosis.
Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies.
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
Anti-arthritic effects of crocin in interleukin-1β-treated articular chondrocytes and cartilage in a rabbit osteoarthritic model.
CD133 affects the invasive ability of HCT116 cells by regulating TIMP-2.
MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1.
Ma J, Hu X, Dai B, Wang Q, Wang H
PeerJ 2021;9:e11259
PeerJ 2021;9:e11259
RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7.
Cheng J, Duan X, Fu X, Jiang Y, Yang P, Cao C, Li Q, Zhang J, Hu X, Zhang X, Ao Y
Frontiers in cell and developmental biology 2021;9:638382
Frontiers in cell and developmental biology 2021;9:638382
Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF-κB and PI3K/AKT Pathways.
Chen GY, Chen JQ, Liu XY, Xu Y, Luo J, Wang YF, Zhou TL, Yan ZR, Zhou L, Tao QW
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6634837
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6634837
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Pei W, Huang X, Ni B, Zhang R, Niu G, You H
Frontiers in pharmacology 2021;12:730312
Frontiers in pharmacology 2021;12:730312
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation.
Aihaiti Y, Song Cai Y, Tuerhong X, Ni Yang Y, Ma Y, Shi Zheng H, Xu K, Xu P
Frontiers in pharmacology 2021;12:672054
Frontiers in pharmacology 2021;12:672054
Chondroprotective and antiarthritic effects of galangin in osteoarthritis: An in vitro and in vivo study.
Huang X, Pei W, Ni B, Zhang R, You H
European journal of pharmacology 2021 Sep 5;906:174232
European journal of pharmacology 2021 Sep 5;906:174232
Pterostilbene Attenuates Particulate Matter-Induced Oxidative Stress, Inflammation and Aging in Keratinocytes.
Teng WL, Huang PH, Wang HC, Tseng CH, Yen FL
Antioxidants (Basel, Switzerland) 2021 Sep 29;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 29;10(10)
Oleanolic Acid Nanofibers Attenuated Particulate Matter-Induced Oxidative Stress in Keratinocytes.
Fu H, Yen FL, Huang PH, Yang CY, Yen CH
Antioxidants (Basel, Switzerland) 2021 Sep 2;10(9)
Antioxidants (Basel, Switzerland) 2021 Sep 2;10(9)
Human Exosomes Accelerate Cutaneous Wound Healing by Promoting Collagen Synthesis in a Diabetic Mouse Model.
Zhao B, Zhang X, Zhang Y, Lu Y, Zhang W, Lu S, Fu Y, Zhou Y, Zhang J, Zhang J
Stem cells and development 2021 Sep 15;30(18):922-933
Stem cells and development 2021 Sep 15;30(18):922-933
Curcumol inhibits EBV-positive Nasopharyngeal carcinoma migration and invasion by targeting nucleolin.
Guan X, Yu D, HuangFu M, Huang Z, Dou T, Liu Y, Zhou L, Li X, Wang L, Liu H, Wang J, Chen X
Biochemical pharmacology 2021 Oct;192:114742
Biochemical pharmacology 2021 Oct;192:114742
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro.
Gao XX, Liu CH, Hu ZL, Li HY, Chang X, Li YY, Zhang YY, Zhai Y, Li CQ
Frontiers in bioscience (Landmark edition) 2021 Oct 30;26(10):799-812
Frontiers in bioscience (Landmark edition) 2021 Oct 30;26(10):799-812
Cold exposure and capsaicin promote 1,2-dimethylhyrazine-induced colon carcinogenesis in rats correlates with extracellular matrix remodeling.
Qin JC, Yu WT, Li HX, Liang YQ, Nong FF, Wen B
World journal of gastroenterology 2021 Oct 21;27(39):6615-6630
World journal of gastroenterology 2021 Oct 21;27(39):6615-6630
High fibular osteotomy ameliorates medial compartment knee osteoarthritis in a rabbit model.
Yan F, Zhao X, Duan S, Maimaiti A, Qi Y, Li M, Maimaiti M, Li W
Journal of biomechanics 2021 Nov 9;128:110734
Journal of biomechanics 2021 Nov 9;128:110734
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Zhang Z, Wu H, Huang S, Chen L, Chen X, Zhang W, Liao L, Zhang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111476
Magnolin exhibits anti-inflammatory effects on chondrocytes via the NF-κB pathway for attenuating anterior cruciate ligament transection-induced osteoarthritis.
Xu K, Gao Y, Yang L, Liu Y, Wang C
Connective tissue research 2021 Jul;62(4):475-484
Connective tissue research 2021 Jul;62(4):475-484
MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases.
Shi Y, He W, Zhong M, Yu M
Genomics 2021 Jul;113(4):1988-1998
Genomics 2021 Jul;113(4):1988-1998
METTL3 involves the progression of osteoarthritis probably by affecting ECM degradation and regulating the inflammatory response.
Sang W, Xue S, Jiang Y, Lu H, Zhu L, Wang C, Ma J
Life sciences 2021 Aug 1;278:119528
Life sciences 2021 Aug 1;278:119528
Novel histopathological classification of meningiomas based on dural invasion.
Murase M, Tamura R, Kuranari Y, Sato M, Ohara K, Morimoto Y, Yoshida K, Toda M
Journal of clinical pathology 2021 Apr;74(4):238-243
Journal of clinical pathology 2021 Apr;74(4):238-243
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
Li JW, Wang RL, Xu J, Sun KY, Jiang HM, Sun ZY, Lv ZY, Xu XQ, Wu R, Guo H, Jiang Q, Shi DQ
Acta pharmacologica Sinica 2021 Apr 8;
Acta pharmacologica Sinica 2021 Apr 8;
Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway.
He X, Huang Z, Liu P, Li Q, Wang M, Qiu M, Xiong Z, Yang S
BioMed research international 2020;2020:3126182
BioMed research international 2020;2020:3126182
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Sun L, Qu L, Brigstock DR, Li H, Li Y, Gao R
International journal of medical sciences 2020;17(1):137-144
International journal of medical sciences 2020;17(1):137-144
UVA influenced the SIRT1-miR-27a-5p-SMAD2-MMP1/COL1/BCL2 axis in human skin primary fibroblasts.
Jiang SB, Lu YS, Liu T, Li LM, Wang HX, Wu Y, Gao XH, Chen HD
Journal of cellular and molecular medicine 2020 Sep;24(17):10027-10041
Journal of cellular and molecular medicine 2020 Sep;24(17):10027-10041
Long-wave Ultraviolet Ray Promotes Inflammation in Keloid-derived Fibroblasts by Activating P38-NFκB1 Signaling Pathway.
Niu X, Lin X, Chen X, Xu S, Huang Z, Tang Q
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
Journal of burn care & research : official publication of the American Burn Association 2020 Nov 30;41(6):1231-1239
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner.
Li J, Liu X, Zang S, Zhou J, Zhang F, Sun B, Qi D, Li X, Kong J, Jin D, Yang X, Luo Y, Lu Y, Lin B, Niu W, Liu T
Cancer letters 2020 Nov 1;492:71-83
Cancer letters 2020 Nov 1;492:71-83
Molecular hydrogen regulates PTEN-AKT-mTOR signaling via ROS to alleviate peritoneal dialysis-related peritoneal fibrosis.
Lu H, Chen W, Liu W, Si Y, Zhao T, Lai X, Kang Z, Sun X, Guo Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4134-4146
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4134-4146
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, Tian L, Chen X, Liu B, Yu X, Li S, Guo S, Wang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
ETV4 overexpression promotes progression of non-small cell lung cancer by upregulating PXN and MMP1 transcriptionally.
Wang Y, Ding X, Liu B, Li M, Chang Y, Shen H, Xie SM, Xing L, Li Y
Molecular carcinogenesis 2020 Jan;59(1):73-86
Molecular carcinogenesis 2020 Jan;59(1):73-86
4-Hydroxy-7-oxo-5-heptenoic acid lactone is a potent inducer of brain cancer cell invasiveness that may contribute to the failure of anti-angiogenic therapies.
Tomko N, Kluever M, Wu C, Zhu J, Wang Y, Salomon RG
Free radical biology & medicine 2020 Jan;146:234-256
Free radical biology & medicine 2020 Jan;146:234-256
Intra-articular collagenase in the spinal facet joint induces pain, DRG neuron dysregulation and increased MMP-1 absent evidence of joint destruction.
Ita ME, Ghimire P, Welch RL, Troche HR, Winkelstein BA
Scientific reports 2020 Dec 15;10(1):21965
Scientific reports 2020 Dec 15;10(1):21965
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo.
Schoenenberger AD, Tempfer H, Lehner C, Egloff J, Mauracher M, Bird A, Widmer J, Maniura-Weber K, Fucentese SF, Traweger A, Silvan U, Snedeker JG
Biomaterials 2020 Aug;249:120034
Biomaterials 2020 Aug;249:120034
Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway.
Yang YF, Chang YC, Jan YH, Yang CJ, Huang MS, Hsiao M
Oncogenesis 2020 Aug 29;9(8):78
Oncogenesis 2020 Aug 29;9(8):78
p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes.
Huang X, You Y, Xi Y, Ni B, Chu X, Zhang R, You H
Inflammation 2020 Apr;43(2):619-628
Inflammation 2020 Apr;43(2):619-628
Protective effects of Erdosteine on interleukin-1β-stimulated inflammation via inhibiting the activation of MAPK, NF-κB, and Wnt/β-catenin signaling pathways in rat osteoarthritis.
Xi Y, Huang X, Tan G, Chu X, Zhang R, Ma X, Ni B, You H
European journal of pharmacology 2020 Apr 15;873:172925
European journal of pharmacology 2020 Apr 15;873:172925
Intravaginal Administration of Human Type III Collagen-Derived Biomaterial with High Cell-Adhesion Activity to Treat Vaginal Atrophy in Rats.
You S, Liu S, Dong X, Li H, Zhu Y, Hu L
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
ACS biomaterials science & engineering 2020 Apr 13;6(4):1977-1988
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
Wang S, Yao Y, Wang X, Zheng G, Ouyang W, Chen W
American journal of cancer research 2019;9(10):2140-2155
American journal of cancer research 2019;9(10):2140-2155
Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis.
Liu X, Zhou ZH, Li W, Zhang SK, Li J, Zhou MJ, Song JW
Frontiers in oncology 2019;9:216
Frontiers in oncology 2019;9:216
Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1/Smad Pathway.
Yao H, Wei S, Xiang Y, Wu Z, Liu W, Wang B, Li X, Xu H, Zhao J, Gao Y
Evidence-based complementary and alternative medicine : eCAM 2019;2019:5124026
Evidence-based complementary and alternative medicine : eCAM 2019;2019:5124026
Tricetin Protects Rat Chondrocytes against IL-1β-Induced Inflammation and Apoptosis.
Sun FF, Hu PF, Xiong Y, Bao JP, Qian J, Wu LD
Oxidative medicine and cellular longevity 2019;2019:4695381
Oxidative medicine and cellular longevity 2019;2019:4695381
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202
PloS one 2019;14(9):e0222202
Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes.
Tu C, Huang X, Xiao Y, Song M, Ma Y, Yan J, You H, Wu H
Frontiers in pharmacology 2019;10:41
Frontiers in pharmacology 2019;10:41
Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43.
Chen Y, Liu H, Huang H, Ma Y, Wang R, Hu Y, Zheng X, Chen C, Tang H
Frontiers in pharmacology 2019;10:1574
Frontiers in pharmacology 2019;10:1574
Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes.
Tu C, Ma Y, Song M, Yan J, Xiao Y, Wu H
European journal of pharmacology 2019 Sep 5;858:172445
European journal of pharmacology 2019 Sep 5;858:172445
Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways.
Huang X, Xi Y, Mao Z, Chu X, Zhang R, Ma X, Ni B, Cheng H, You H
European journal of pharmacology 2019 Sep 15;859:172481
European journal of pharmacology 2019 Sep 15;859:172481
Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells.
Cecen B, Keles D, Oktay G, Kozaci LD
Chemico-biological interactions 2019 Sep 1;310:108730
Chemico-biological interactions 2019 Sep 1;310:108730
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
Liang S, Wang ZG, Zhang ZZ, Chen K, Lv ZT, Wang YT, Cheng P, Sun K, Yang Q, Chen AM
Aging 2019 Oct 11;11(19):8664-8680
Aging 2019 Oct 11;11(19):8664-8680
NOV/CCN3 induces cartilage protection by inhibiting PI3K/AKT/mTOR pathway.
Huang X, Ni B, Mao Z, Xi Y, Chu X, Zhang R, Ma X, You H
Journal of cellular and molecular medicine 2019 Nov;23(11):7525-7534
Journal of cellular and molecular medicine 2019 Nov;23(11):7525-7534
Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats.
Yu H, Zeng R, Lin Y, Li X, Tasneem S, Yang Z, Qiu YX, Li B, Wang YH, Cai X, Wang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 May;58:152876
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 May;58:152876
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway.
Wang S, Yao Y, Rao C, Zheng G, Chen W
International journal of oncology 2019 Mar;54(3):966-980
International journal of oncology 2019 Mar;54(3):966-980
MiR-202-3p regulates interleukin-1β-induced expression of matrix metalloproteinase 1 in human nucleus pulposus.
Shi C, Wu L, Lin W, Cai Y, Zhang Y, Hu B, Gao R, Im HJ, Yuan W, Ye X, van Wijnen AJ
Gene 2019 Mar 1;687:156-165
Gene 2019 Mar 1;687:156-165
Liraglutide alleviates cardiac fibrosis through inhibiting P4hα-1 expression in STZ-induced diabetic cardiomyopathy.
Zhao T, Chen H, Xu F, Wang J, Liu Y, Xing X, Guo L, Zhang M, Lu Q
Acta biochimica et biophysica Sinica 2019 Mar 1;51(3):293-300
Acta biochimica et biophysica Sinica 2019 Mar 1;51(3):293-300
Concentration dependent effects of fibroblast-like synoviocytes on collagen gel multiscale biomechanics & neuronal signaling: Implications for modeling human ligamentous tissues.
Ita M, Winkelstein BA
Journal of biomechanical engineering 2019 Jun 18;
Journal of biomechanical engineering 2019 Jun 18;
Overexpressed vascular endothelial growth factor in adipose derived stem cells attenuates fibroblasts and skin injuries by ultraviolet radiation.
Xie X, Wang Y, Xia Y, Mao Y
Bioscience reports 2019 Jul 31;39(7)
Bioscience reports 2019 Jul 31;39(7)
Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity.
Zhang T, Li Q, Wang L, Li G
Experimental and therapeutic medicine 2019 Jan;17(1):181-186
Experimental and therapeutic medicine 2019 Jan;17(1):181-186
ZRANB2/SNHG20/FOXK1 Axis regulates Vasculogenic mimicry formation in glioma.
Li X, Xue Y, Liu X, Zheng J, Shen S, Yang C, Chen J, Li Z, Liu L, Ma J, Ma T, Liu Y
Journal of experimental & clinical cancer research : CR 2019 Feb 11;38(1):68
Journal of experimental & clinical cancer research : CR 2019 Feb 11;38(1):68
Isorhapontigenin Suppresses Interleukin-1β-Induced Inflammation and Cartilage Matrix Damage in Rat Chondrocytes.
Ma Y, Tu C, Liu W, Xiao Y, Wu H
Inflammation 2019 Dec;42(6):2278-2285
Inflammation 2019 Dec;42(6):2278-2285
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H
Aging 2019 Dec 16;11(24):12532-12545
Aging 2019 Dec 16;11(24):12532-12545
Induction of Fibroblast Senescence During Mouse Corneal Wound Healing.
Wang X, Qu M, Li J, Danielson P, Yang L, Zhou Q
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Investigative ophthalmology & visual science 2019 Aug 1;60(10):3669-3679
Effects of growth hormone and functional appliance on mandibular growth in an adolescent rat model.
Wang S, Ye L, Li M, Zhan H, Ye R, Li Y, Zhao Z
The Angle orthodontist 2018 Sep;88(5):624-631
The Angle orthodontist 2018 Sep;88(5):624-631
Kaempferol inhibits interleukin‑1β stimulated matrix metalloproteinases by suppressing the MAPK‑associated ERK and P38 signaling pathways.
Huang X, Pan Q, Mao Z, Wang P, Zhang R, Ma X, Chen J, You H
Molecular medicine reports 2018 Sep;18(3):2697-2704
Molecular medicine reports 2018 Sep;18(3):2697-2704
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families.
He XX, Shi LL, Qiu MJ, Li QT, Wang MM, Xiong ZF, Yang SL
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
Biochemical and biophysical research communications 2018 Oct 12;504(4):878-884
Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes.
Huang X, Xi Y, Pan Q, Mao Z, Zhang R, Ma X, You H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:433-439
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:433-439
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Wen W, Chen J, Ding L, Luo X, Zheng X, Dai Q, Gu Q, Liu C, Liang M, Guo X, Liu P, Li M
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Archives of biochemistry and biophysics 2018 Nov 1;657:31-40
Investigation of the expressions of MMPs and TIMPs between isogeneic and allogeneic rat aortic transplantation.
Wei SD, Cao D, Xu XS, Bai H, Wu H, Wang MH
Molecular medicine reports 2018 May;17(5):6909-6913
Molecular medicine reports 2018 May;17(5):6909-6913
Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis.
Li JJ, Yin HK, Guan DX, Zhao JS, Feng YX, Deng YZ, Wang X, Li N, Wang XF, Cheng SQ, Bao Y, Xie D
British journal of cancer 2018 May;118(10):1337-1348
British journal of cancer 2018 May;118(10):1337-1348
Sinapic Acid Inhibits the IL-1β-Induced Inflammation via MAPK Downregulation in Rat Chondrocytes.
Huang X, Pan Q, Mao Z, Zhang R, Ma X, Xi Y, You H
Inflammation 2018 Mar;41(2):562-568
Inflammation 2018 Mar;41(2):562-568
Protective effects of psoralidin on IL‑1β‑induced chondrocyte apoptosis.
Rao Z, Wang S, Wang J
Molecular medicine reports 2018 Feb;17(2):3418-3424
Molecular medicine reports 2018 Feb;17(2):3418-3424
Cellular communication promotes mammosphere growth and collective invasion through microtubule‑like structures and angiogenesis.
Huang S, Yuan N, Wang G, Wu F, Feng L, Luo M, Li M, Luo A, Zhao X, Zhang L
Oncology reports 2018 Dec;40(6):3297-3312
Oncology reports 2018 Dec;40(6):3297-3312
Overexpression of matrix metalloproteinase-9 in adolescents with primary spontaneous pneumothorax for surgical intervention.
Chiu CY, Chen TP, Chen JR, Wang CJ, Yin SY, Lai SH, Wong KS
The Journal of thoracic and cardiovascular surgery 2018 Dec;156(6):2328-2336.e2
The Journal of thoracic and cardiovascular surgery 2018 Dec;156(6):2328-2336.e2
Tumor cell density regulates matrix metalloproteinases for enhanced migration.
Jayatilaka H, Umanzor FG, Shah V, Meirson T, Russo G, Starich B, Tyle P, Lee JSH, Khatau S, Gil-Henn H, Wirtz D
Oncotarget 2018 Aug 24;9(66):32556-32569
Oncotarget 2018 Aug 24;9(66):32556-32569
Myosin 1b promotes cell proliferation, migration, and invasion in cervical cancer.
Zhang HR, Lai SY, Huang LJ, Zhang ZF, Liu J, Zheng SR, Ding K, Bai X, Zhou JY
Gynecologic oncology 2018 Apr;149(1):188-197
Gynecologic oncology 2018 Apr;149(1):188-197
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Zeng L, Xiao CZ, Deng ZT, Li RH
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8985623
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8985623
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Chiu HW, Chen CH, Chen YJ, Hsu YH
PloS one 2017;12(3):e0174042
PloS one 2017;12(3):e0174042
Collagen I promotes hepatocellular carcinoma cell proliferation by regulating integrin β1/FAK signaling pathway in nonalcoholic fatty liver.
Zheng X, Liu W, Xiang J, Liu P, Ke M, Wang B, Wu R, Lv Y
Oncotarget 2017 Nov 10;8(56):95586-95595
Oncotarget 2017 Nov 10;8(56):95586-95595
Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation.
Zhao S, Zhao Y, Guo J, Fei C, Zheng Q, Li X, Chang C
Scientific reports 2017 Mar 6;7:43849
Scientific reports 2017 Mar 6;7:43849
Pigment Epithelium-Derived Factor (PEDF) mediates cartilage matrix loss in an age-dependent manner under inflammatory conditions.
Nakamura DS, Hollander JM, Uchimura T, Nielsen HC, Zeng L
BMC musculoskeletal disorders 2017 Jan 25;18(1):39
BMC musculoskeletal disorders 2017 Jan 25;18(1):39
MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN.
Chen L, Li Q, Wang J, Jin S, Zheng H, Lin J, He F, Zhang H, Ma S, Mei J, Yu J
Journal of cellular and molecular medicine 2017 Dec;21(12):3347-3359
Journal of cellular and molecular medicine 2017 Dec;21(12):3347-3359
Long Non-Coding RNA BANCR Promotes Endometrial Cancer Cell Proliferation and Invasion by Regulating MMP2 and MMP1 via ERK/MAPK Signaling Pathway.
Wang D, Wang D, Wang N, Long Z, Ren X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):644-656
Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma.
Li F, Fang Z, Zhang J, Li C, Liu H, Xia J, Zhu H, Guo C, Qin Z, Li F, Han X, Wang Y, Feng Y, Wang Y, Zhang W, Wang Z, Jin Y, Sun Y, Wei W, Zeng R, Chen H, Ji H
Cell research 2016 Oct;26(10):1149-1164
Cell research 2016 Oct;26(10):1149-1164
CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis.
Zhuang K, Zhang J, Xiong M, Wang X, Luo X, Han L, Meng Y, Zhang Y, Liao W, Liu S
Cell death & disease 2016 Oct 13;7(10):e2415
Cell death & disease 2016 Oct 13;7(10):e2415
Conditional knockout of tissue factor pathway inhibitor 2 in vascular endothelial cells accelerates atherosclerotic plaque development in mice.
Hong J, Liu R, Chen L, Wu B, Yu J, Gao W, Pan J, Luo X, Shi H
Thrombosis research 2016 Jan;137:148-156
Thrombosis research 2016 Jan;137:148-156
Heme oxygenase-1 attenuates IL-1β induced alteration of anabolic and catabolic activities in intervertebral disc degeneration.
Hu B, Shi C, Xu C, Cao P, Tian Y, Zhang Y, Deng L, Chen H, Yuan W
Scientific reports 2016 Feb 15;6:21190
Scientific reports 2016 Feb 15;6:21190
The trophoblast plug during early pregnancy: a deeper insight.
Weiss G, Sundl M, Glasner A, Huppertz B, Moser G
Histochemistry and cell biology 2016 Dec;146(6):749-756
Histochemistry and cell biology 2016 Dec;146(6):749-756
Metallothionein-3 Increases Triple-Negative Breast Cancer Cell Invasiveness via Induction of Metalloproteinase Expression.
Kmiecik AM, Pula B, Suchanski J, Olbromski M, Gomulkiewicz A, Owczarek T, Kruczak A, Ambicka A, Rys J, Ugorski M, Podhorska-Okolow M, Dziegiel P
PloS one 2015;10(5):e0124865
PloS one 2015;10(5):e0124865
Effects of small interfering RNA-mediated downregulation of the Krüppel-like factor 4 gene on collagen metabolism in human hepatic stellate cells.
Li T, Niu L, Li M, Liu Y, Xu Z, Gao X, Liu D
Molecular medicine reports 2015 Sep;12(3):3972-3978
Molecular medicine reports 2015 Sep;12(3):3972-3978
Potent effects of dioscin against liver fibrosis.
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies.
Wu DQ, Zhong HM, Ding QH, Ba L
BMC complementary and alternative medicine 2014 Nov 15;14:444
BMC complementary and alternative medicine 2014 Nov 15;14:444
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
Ding QH, Cheng Y, Chen WP, Zhong HM, Wang XH
European journal of pharmacology 2013 May 15;708(1-3):1-7
European journal of pharmacology 2013 May 15;708(1-3):1-7
Anti-arthritic effects of crocin in interleukin-1β-treated articular chondrocytes and cartilage in a rabbit osteoarthritic model.
Ding Q, Zhong H, Qi Y, Cheng Y, Li W, Yan S, Wang X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013 Jan;62(1):17-25
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013 Jan;62(1):17-25
CD133 affects the invasive ability of HCT116 cells by regulating TIMP-2.
Zhang M, Liu Y, Feng H, Bian X, Zhao W, Yang Z, Gu B, Li Z, Liu Y
The American journal of pathology 2013 Feb;182(2):565-76
The American journal of pathology 2013 Feb;182(2):565-76
MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1.
Wu J, Wu G, Lv L, Ren YF, Zhang XJ, Xue YF, Li G, Lu X, Sun Z, Tang KF
Carcinogenesis 2012 Mar;33(3):519-28
Carcinogenesis 2012 Mar;33(3):519-28
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 10371-2-AP(MMP1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using MMP1 antibody 10371-2-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-MMP1 (IP:10371-2-AP, 4ug; Detection:10371-2-AP 1:1000) with A549 cells lysate 1200ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 10371-2-AP(MMP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 10371-2-AP(MMP1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue