BS6652

antibody from Bioworld Technology, Inc
Targeting: LIG1
Provider product page for BS6652
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6652 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DNA Ligase I polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human DNA Ligase I.
Description
Eukaryotic DNA ligases are ATP-dependent enzymes that catalyse the joining of single and double-strand DNA breaks, which is an essential final step in DNA replication, recombination and repair. Four biochemically distinct DNA ligases, termed ligases I-IV, have been identified in mammalian cells. DNA ligase I is functionally homologous to the DNA ligase encoded by the Saccharomyces cerevisiae Cdc9 gene. The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is due to DNA ligase I. A combination of DNA polymerase epsilon, PCNA, replication factor C, replication protein A, and DNA ligase I is well-suited to the task of creating nucleotide excision repair patches.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
LIG1 protein structure - BS6652 shown in red.