MAB262

antibody from R&D Systems

Targeting: AREG AREGB, SDGF

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB262

Provider

R&D Systems

Product name

Anti-Human Amphiregulin Monoclonal Antibody (Clone 31221)

Antibody type

Monoclonal

Antigen

E. coli-derived recombinant human Amphiregulin

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Isotype

IgG

Vial size

500 µg

References

Submitted references

Multiple myeloma-derived exosomes are enriched of amphiregulin (AREG) and activate the epidermal growth factor pathway in the bone microenvironment leading to osteoclastogenesis.

Raimondo S, Saieva L, Vicario E, Pucci M, Toscani D, Manno M, Raccosta S, Giuliani N, Alessandro R
Journal of hematology & oncology 2019 Jan 8;12(1):2

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CRB3 and the FERM protein EPB41L4B regulate proliferation of mammary epithelial cells through the release of amphiregulin.

Walker SJ, Selfors LM, Margolis BL, Brugge JS
PloS one 2018;13(11):e0207470

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Membrane-Tethered Intracellular Domain of Amphiregulin Promotes Keratinocyte Proliferation.

Stoll SW, Stuart PE, Lambert S, Gandarillas A, Rittié L, Johnston A, Elder JT
The Journal of investigative dermatology 2016 Feb;136(2):444-452

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Amphiregulin carboxy-terminal domain is required for autocrine keratinocyte growth.

Stoll SW, Johnson JL, Li Y, Rittié L, Elder JT
The Journal of investigative dermatology 2010 Aug;130(8):2031-40

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Development and validation of sandwich ELISA microarrays with minimal assay interference.

Gonzalez RM, Seurynck-Servoss SL, Crowley SA, Brown M, Omenn GS, Hayes DF, Zangar RC
Journal of proteome research 2008 Jun;7(6):2406-14