BS4799

antibody from Bioworld Technology, Inc

Targeting: MARCKS 80K-L, MACS, PKCSL

Immunohistochemistry

Antibody data

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Validation data

Product number: BS4799 - Provider product page
Provider: Bioworld Technology, Inc
Product name: MARCKS (phospho S163) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic phosphopeptide derived from human MARCKS around the phosphorylation site of Serine 163.
Description: Myristoylated alanine-rich protein kinase C substrate (MARCKS), also designated 80K or 80K-L, has been identified as a major cellular substrate for protein kinase C. Human MARCKS is a 332 amino acid protein with a calculated molecular weight of 31.534 kDa; however, it has been shown to run at 80-87 kDa on Western blot. The plasma membrane bound protein dissociates from the membrane upon phosphorylation by various PKC isoforms. In NIH/3T3 fibroblasts, PKC Ï« and PKC ÷, but not PKC Ñ´, are responsible for MARCKS phosphorylation. MARCKS has been found to bind calmodulin, Actin and Synapsin and is a filamentous (F) Actin crosslinking protein.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

MARCKS protein structure - BS4799 shown in red.