Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
PDX1
Pancreatic and duodenal homeobox 1IDX-1, IPF1, MODY4, PDX-1, STF-1
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]
Top validated antibodies |
|||||
| Novus Biologicals |  AF2419 |
21 references | Polyclonal |
WB
ICC
IHC
|
|
| R&D Systems | AF2419 |
17 references | Polyclonal |
WB
ICC
IHC
|
|
| antibodies-online | ABIN969554 |
2 references | Monoclonal |
WB
EL
FC
|
|
| OriGene | TA500038 |
1 references | Monoclonal |
WB
ICC
IHC
|
|
| LSBio | LS-C784069 |
Monoclonal |
WB
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider