329502

antibody from BioLegend

Targeting: CD244 2B4, NAIL, NKR2B4, Nmrk, SLAMF4

Western blot

Antibody data

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Validation data

Product number: 329502 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#329502, RRID:AB_1279194
Product name: Purified anti-human CD244 (2B4)
Antibody type: Monoclonal
Antigen: CD244 (2B4)
Description: CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including majority of CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C.

CD244 protein structure - 329502 shown in red.