Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
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- Product number
- AB0041-200 - Provider product page
- Provider
- SICGEN
- Proper citation
- SICGEN Cat#AB0041-200, RRID:AB_2333115
- Product name
- Anti-CANX
- Antibody type
- Polyclonal
- Description
- Goat polyclonal to CANX (Calnexin) - endoplasmic reticulum (ER) membrane marker. CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep, Simian, Other
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 400 µg
- Concentration
- 2 mg/ml
- Storage
- Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin.
Human γδ thymocytes are functionally immature and differentiate into cytotoxic type 1 effector T cells upon IL-2/IL-15 signaling.
Martins-Marques T, Pinho MJ, Zuzarte M, Oliveira C, Pereira P, Sluijter JP, Gomes C, Girao H
Journal of extracellular vesicles 2016 Sep 29;5:32538
Journal of extracellular vesicles 2016 Sep 29;5:32538
Human γδ thymocytes are functionally immature and differentiate into cytotoxic type 1 effector T cells upon IL-2/IL-15 signaling.
Ribot JC, Ribeiro ST, Correia DV, Sousa AE, Silva-Santos B
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 1;192(5):2237-43
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 1;192(5):2237-43
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Supportive validation
- Submitted by
- SICGEN (provider)
- Main image
- Experimental details
- lysates at 50 µg per lane
- Sample type
- HaCat and HeLa cell lines
- Primary Ab dilution
- 1/500
- Conjugate
- Unconjugated
- Secondary Ab
- Secondary Ab
- Secondary Ab dilution
- 1/10,000
Supportive validation
- Submitted by
- SICGEN (provider)
- Main image
- Experimental details
- Cells fixed with 4% PFA
- Sample type
- Hepa1-6
- Primary Ab dilution
- 1/100
- Conjugate
- Unconjugated