ABIN350080

antibody from antibodies-online

Targeting: SLC18A3 VACHT

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN350080

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN350080, RRID:AB_10781319

Product name

anti-Activity-Regulated Cytoskeleton-Associated Protein (Arc) (Arg3) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide from human Arg3.1 (ARC) was used as the antigen. The peptide is homologous in rat and mouse.

Reactivity

Human, Mouse, Rat

Host

Goat

Epitope

Arg3

Vial size

100 μL

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.

Handling

Avoid freeze and thaw cycles.

References

Submitted references

Tinnitus behavior and hearing function correlate with the reciprocal expression patterns of BDNF and Arg3.1/arc in auditory neurons following acoustic trauma.

Tan J, Rüttiger L, Panford-Walsh R, Singer W, Schulze H, Kilian SB, Hadjab S, Zimmermann U, Köpschall I, Rohbock K, Knipper M
Neuroscience 2007 Mar 16;145(2):715-26

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Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors.

Shepherd JD, Rumbaugh G, Wu J, Chowdhury S, Plath N, Kuhl D, Huganir RL, Worley PF
Neuron 2006 Nov 9;52(3):475-84

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Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission.

Rial Verde EM, Lee-Osbourne J, Worley PF, Malinow R, Cline HT
Neuron 2006 Nov 9;52(3):461-74

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Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking.

Chowdhury S, Shepherd JD, Okuno H, Lyford G, Petralia RS, Plath N, Kuhl D, Huganir RL, Worley PF
Neuron 2006 Nov 9;52(3):445-59