DYNC1LI1

The protein encoded by this gene belongs to light intermediate subunit family, whose members are components of the multiprotein cytoplasmic dynein complex, which is involved in intracellular trafficking and chromosome segregation during mitosis. The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles. The protein may also mediate binding to other cargo molecules to facilitate intracellular vesicle trafficking. [provided by RefSeq, Jul 2016]

Description

Dynein cytoplasmic 1 light intermediate chain 1

Tissue specificity

Low tissue specificity

Subcell location

Centrosome, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

3 (32525974 - 32570858)

Ensembl ID

ENSG00000144635  (ver. 103.38)

Orthologs

Mouse Dync1li1: ENSMUSG00000032435

UniProt

Q9Y6G9

neXtProt

NX_Q9Y6G9

Human splice variants
Mouse splice variants

Protein structure