BS1290

antibody from Bioworld Technology, Inc

Targeting: PDGFB SIS, SSV

Immunohistochemistry

Antibody data

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Validation data

Product number: BS1290 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS1290, RRID:AB_1663404
Product name: PDGF B (L48) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 21-70 of Human PDGF-B.
Description: PDGF is a mitogen for mesenchyme- and glia-derived cells. It consists of two disulfide-bonded polypeptide chains, A and B, and occurs as three isoforms, PDGF AA, PDGF AB and PDGF BB. The three isoforms bind with different affinities to two receptor types, Ï« and ÉÇ, which are structurally related and endowed with protein-tyrosine kinase domains. Ligand binding induces activation of the receptor kinases by formation of receptor dimers; the A subunit of PDGF binds only to Ï« receptors with high affinity, whereas the B subunit can bind to both Ï« and ÉÇ receptors. Evidence suggests that PDGF may function as a neurotrophic factor.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

PDGFB protein structure - BS1290 shown in red.