Explore
Validate
Learn
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- GTX61796 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX61796, RRID:AB_10621134
- Product name
- Histone H2A.XS139ph (phospho Ser139) antibody [EP854(2)Y]
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Cell Supernatant
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Storage
- Store at -20 °C. Stable for 12 months from date of receipt.
Submitted references A novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity.
The G2 checkpoint inhibitor CBP-93872 increases the sensitivity of colorectal and pancreatic cancer cells to chemotherapy.
Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.
A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines.
Differential roles for Chk1 and FANCD2 in ATR-mediated signalling for psoralen photoactivation-induced senescence.
Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation.
Yusenko M, Jakobs A, Klempnauer KH
Scientific reports 2018 Sep 3;8(1):13159
Scientific reports 2018 Sep 3;8(1):13159
The G2 checkpoint inhibitor CBP-93872 increases the sensitivity of colorectal and pancreatic cancer cells to chemotherapy.
Iwata T, Uchino T, Koyama A, Johmura Y, Koyama K, Saito T, Ishiguro S, Arikawa T, Komatsu S, Miyachi M, Sano T, Nakanishi M, Shimada M
PloS one 2017;12(5):e0178221
PloS one 2017;12(5):e0178221
Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.
Henrich SM, Usadel C, Werwein E, Burdova K, Janscak P, Ferrari S, Hess D, Klempnauer KH
Scientific reports 2017 Jan 27;7:41663
Scientific reports 2017 Jan 27;7:41663
A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
Ben Younes K, Body S, Costé É, Viailly PJ, Miloudi H, Coudre C, Jardin F, Ben Aissa-Fennira F, Sola B
BMC cancer 2017 Aug 10;17(1):538
BMC cancer 2017 Aug 10;17(1):538
The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines.
Perrigue PM, Silva ME, Warden CD, Feng NL, Reid MA, Mota DJ, Joseph LP, Tian YI, Glackin CA, Gutova M, Najbauer J, Aboody KS, Barish ME
Molecular cancer research : MCR 2015 Apr;13(4):636-50
Molecular cancer research : MCR 2015 Apr;13(4):636-50
Differential roles for Chk1 and FANCD2 in ATR-mediated signalling for psoralen photoactivation-induced senescence.
Hovest MG, Krieg T, Herrmann G
Experimental dermatology 2011 Nov;20(11):883-9
Experimental dermatology 2011 Nov;20(11):883-9
Human condensin function is essential for centromeric chromatin assembly and proper sister kinetochore orientation.
Samoshkin A, Arnaoutov A, Jansen LE, Ouspenski I, Dye L, Karpova T, McNally J, Dasso M, Cleveland DW, Strunnikov A
PloS one 2009 Aug 28;4(8):e6831
PloS one 2009 Aug 28;4(8):e6831
No comments: Submit comment
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- A. Western blot analysis on Jurkat cell lysates using anti-Phospho-H2A.x (pS139) RabMAb (cat. #GTX61796). Cells were either (A) untreated (B) treated with etoposide
- Validation comment
- WB
