ACAD9

This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

Description

Acyl-CoA dehydrogenase family member 9

Tissue specificity

Low tissue specificity

Subcell location

Mitochondria

Predicted location

Intracellular

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

3 (128879596 - 128924003)

Ensembl ID

ENSG00000177646  (ver. 103.38)

Orthologs

Mouse Acad9: ENSMUSG00000027710

UniProt

Q9H845

neXtProt

NX_Q9H845

Human splice variants
Mouse splice variants

Protein structure