RB-22-0001-100

antibody from RayBiotech, Inc.

Targeting: FN1 CIG, FINC, GFND2, LETS, MSF

ELISA (Recommended by provider)

Antibody Data

Product number

RB-22-0001-100

Provider

RayBiotech, Inc.

Product name

Rabbit anti-Fibronectin

Antibody type

Polyclonal

Antigen

The imunogen was synthetic peptide.

Description

Plasma fibronectin level is elevated in severe coronary artery disease. Increased plasma fibronectin levels are related with venous thromboembolism (VTE) particularly in males, and extend the probable association between biomarkers and risk factors for arterial atherothrombosis and VTE. Fibronectin plays a role in several cellular processes, including tissue repair, embryogenesis, blood clotting, and cell migration/adhesion. Fibronectin exists in two main forms: 1) as an insoluble glycoprotein dimer that serves as a linker in the extracellular matrix and 2) as a soluble disulfide linked dimer in plasma. The plasma form is produced by hepatocytes, and the ECM form is synthesized by fibroblasts, chondrocytes, endothelial cells, macrophages, as well as certain epithelial cells. Fibronectin also takes part as a general cell adhesion molecule by anchoring cells to collagen or proteoglycan substrates. Fibronectin organizes cellular interaction with the ECM by binding to different components of the extracellular matrix and to membrane-bound Fibronectin receptors on cell surfaces. Molecular Weight = 450kDa. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography.

Reactivity

Human

Host

Rabbit

Conjugate

Biotin

Antigen sequence

This antibody was produced from a r
abbit immunized with the immunogen.
The IgG fraction was purified from
rabbit serum followed by Protein A
/G affinity chromatography.


Isotype

IgG

Vial size

100 µg

Handling

Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1x PBS to a final concentration of 1 mg/ml.