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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Immunohistochemistry [1]
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- Product number
- 600-401-265 - Provider product page
- Provider
- Rockland Immunochemicals, Inc.
- Proper citation
- Rockland Cat#600-401-265, RRID:AB_828359
- Product name
- Anti-NFKB p65 (Rel A) pS536 (RABBIT) Antibody - 600-401-265
- Antibody type
- Polyclonal
- Vial size
- 100 µl
Submitted references Linear Polyubiquitin Chain Modification of TDP-43-Positive Neuronal Cytoplasmic Inclusions in Amyotrophic Lateral Sclerosis.
Phosphorylated NF-κB subunit p65 aggregates in granulovacuolar degeneration and neurites in neurodegenerative diseases with tauopathy.
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.
Suppression of Propionibacterium acnes Infection and the Associated Inflammatory Response by the Antimicrobial Peptide P5 in Mice.
Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis.
Nakayama Y, Tsuji K, Ayaki T, Mori M, Tokunaga F, Ito H
Journal of neuropathology and experimental neurology 2020 Mar 1;79(3):256-265
Journal of neuropathology and experimental neurology 2020 Mar 1;79(3):256-265
Phosphorylated NF-κB subunit p65 aggregates in granulovacuolar degeneration and neurites in neurodegenerative diseases with tauopathy.
Yamaguchi Y, Ayaki T, Li F, Tsujimura A, Kamada M, Ito H, Maki T, Sawamoto N, Urushitani M, Takahashi R
Neuroscience letters 2019 Jun 21;704:229-235
Neuroscience letters 2019 Jun 21;704:229-235
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F
Nature communications 2016 Aug 24;7:12547
Nature communications 2016 Aug 24;7:12547
Suppression of Propionibacterium acnes Infection and the Associated Inflammatory Response by the Antimicrobial Peptide P5 in Mice.
Ryu S, Han HM, Song PI, Armstrong CA, Park Y
PloS one 2015;10(7):e0132619
PloS one 2015;10(7):e0132619
Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis.
Manna SK, Aggarwal RS, Sethi G, Aggarwal BB, Ramesh GT
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Apr 1;13(7):2290-7
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Apr 1;13(7):2290-7
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Supportive validation
- Submitted by
- Rockland Immunochemicals, Inc. (provider)
- Main image
- Experimental details
- Rockland's affinity purified anti-p65 (RelA) pS536 antibody was used at 5.0 ?g/ml to detect signal in a variety of tissues including multi-human, multi-brain and multi-cancer slides. This image shows moderate positive staining of human kidney distal tubules and collecting ducts. Tissue was formalin-fixed and paraffin embedded. The image shows localization of the antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain. Personal Communication, Tina Roush, LifeSpanBiosciences, Seattle, WA.
- Validation comment
- Immunohistochemistry
