PA1-011

antibody from Invitrogen Antibodies

Targeting: CRYAB CRYA2, HSPB5

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PA1-011

Provider

Invitrogen Antibodies

Product name

Phospho-CRYAB (Ser45) Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

PA1-011 detects phospho-alpha-B crystallin (Ser45) from bovine, human, mouse and rat samples. This antibody does not detect the unphosphorylated form of the protein.

Concentration

1 mg/mL

References

Submitted references

Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination.

Kuipers HF, Yoon J, van Horssen J, Han MH, Bollyky PL, Palmer TD, Steinman L
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 28;114(9):E1745-E1754

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Hyperglycemia induced expression, phosphorylation, and translocation of αB-crystallin in rat skeletal muscle.

Reddy VS, Jakhotia S, Reddy PY, Reddy GB
IUBMB life 2015 Apr;67(4):291-9

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Expression and induction of small heat shock proteins in rat heart under chronic hyperglycemic conditions.

Reddy VS, Kumar ChU, Raghu G, Reddy GB
Archives of biochemistry and biophysics 2014 Sep 15;558:1-9

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O-GlcNAcylation of αB-crystallin regulates its stress-induced translocation and cytoprotection.

Krishnamoorthy V, Donofrio AJ, Martin JL
Molecular and cellular biochemistry 2013 Jul;379(1-2):59-68

Western blot

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Western blot detection of recombinant bovine phospho-alpha-B crystallin (Ser45) using Product # PA1-011. Lane 1 is phospho-alpha-B crystallin (Ser45) and lane 2 is unphosphorylated alpha-B crystallin.