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- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 356419 - Provider product page
- Provider
- BioLegend
- Product name
- Brilliant Violet 510™ anti-human CD27
- Antibody type
- Monoclonal
- Antigen
- Human T cells from a T-ALL patient.
- Description
- CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70, and plays a role in costimulation of T cell activation and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Antibody clone number
- M-T271
- Vial size
- 25 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were stained with CD27 (clone M-T271) Brilliant Violet 510™ (filled histogram) or mouse IgG1 Brilliant Violet 510™ isotype control (open histogram).
- Conjugate
- Green dye
