302822

antibody from BioLegend
Targeting: CD27 S152, TNFRSF7, Tp55
Provider product page for 302822

Antibody data

Product number
302822 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#302822, RRID:AB_2244308
Product name
Pacific Blue™ anti-human CD27 [O323]
Antibody type
Monoclonal
Antigen
CD27
Description
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Reactivity
Human, Simian
Host
Mouse
Conjugate
Blue dye
Isotype
IgG
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CD27 protein structure - 302822 shown in red.