BS6482

antibody from Bioworld Technology, Inc
Targeting: CD40 Bp50, p50, TNFRSF5
Provider product page for BS6482

Antibody data

Product number
BS6482 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CD40 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CD40.
Description
A receptor ligand pair central to the transmission of this signal is CD40, expressed on the surface of B cells, together with CD40L, expressed on activated T cells. In the presence of such stimulus, IL-4 and IL-13 are capable of triggering immunoglobulin class switching and secretion of IgE. B cells are sensitive to these cytokines only subsequent to CD40/CD40L-driven DNA synthesis. A downstream mediator of the CD40 signaling pathway, designated CRAF, is a member of an expanding family of proteins that contain a conserved cysteine- and histidine-rich RING finger motif. Other members of the family include TRAF1 and TRAF2. The latter proteins have been shown to regulate TNF-R2 as well as CD40 signaling through activation of the NF°ÙB family of transcription factors.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CD40 protein structure - BS6482 shown in red.