360405

antibody from BioLegend
Targeting: IL13RA1 CD213a1, IL-13Ra, NR4
Provider product page for 360405

Antibody data

Product number
360405 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#360405, RRID:AB_2562625
Product name
APC anti-human CD213a1 (IL-13Ra1)
Antibody type
Monoclonal
Antigen
Recombinant extracellular domain of human IL-13 receptor α1 chain
Description
CD213α1, also known as IL-13Rα1, is a subunit of the IL-13R complex. It can heterodimerize with IL-4R and bind IL-13 with high affinity. IL-13Rα1 by itself binds IL-13 with low affinity compared to IL-13Rα2. It is a 48.7 kD, single pass type I membrane protein. It is expressed at low levels on myeloid cells and on activated T and B cells and Th17 cells. It interacts with TYK2 and may lead to activation of JAK1, STAT3, and STAT6 that is induced by IL-13 and IL-4. It has been implicated to have a role in asthma and allergic responses.
Reactivity
Human
Host
Mouse
Conjugate
Red dye
Antibody clone number
SS12B
Vial size
25 tests
Storage
2°C-8°C
Handling
Ambient RT
IL13RA1 protein structure - 360405 shown in red.