BS6377

antibody from Bioworld Technology, Inc
Targeting: MAPK6 ERK3, HsT17250, p97MAPK, PRKM6
Provider product page for BS6377
Western blot

Antibody data

Product number
BS6377 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ERK3 (phospho S189) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human ERK3 around the phosphorylation site of Serine 189.
Description
Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl2 and caspase 3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK3 gene maps to chromosome 15q21 and encodes a 721 amino acid protein.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MAPK6 protein structure - BS6377 shown in red.